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Team:British Columbia
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<img src="https://static.igem.org/mediawiki/2010/5/5d/Bcmov.gif"/> | <img src="https://static.igem.org/mediawiki/2010/5/5d/Bcmov.gif"/> | ||
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<div id="team_box"> | <div id="team_box"> | ||
<center><a href="https://2010.igem.org/Team:British_Columbia/Team"><img src="https://static.igem.org/mediawiki/2010/c/c5/Teambox.jpg" alt=""/></center> | <center><a href="https://2010.igem.org/Team:British_Columbia/Team"><img src="https://static.igem.org/mediawiki/2010/c/c5/Teambox.jpg" alt=""/></center> | ||
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| - | <p> | + | <p>We are 9 undergraduate students, 2 graduate advisors and 2 faculty advisors from various disciplines including Pharmacology, Life Sciences, Physiology, Chemical and Biological Engineering, Materials Engineering, Engineering Physics and Computer Science.<a href="https://2010.igem.org/Team:British_Columbia/Team">Come visit our Team page!</a></p></div> |
<div id="project_box"> <center><a href="https://2010.igem.org/Team:British_Columbia/Project"><img src="https://static.igem.org/mediawiki/2010/a/a8/Projectbox.jpg" alt=""/></center> | <div id="project_box"> <center><a href="https://2010.igem.org/Team:British_Columbia/Project"><img src="https://static.igem.org/mediawiki/2010/a/a8/Projectbox.jpg" alt=""/></center> | ||
</a> | </a> | ||
| - | <p> | + | <p>With the aim of dispersing Staphylococcus aureus biofilms, our team is working to express an endogenous bacteriophage and biofilm matrix-degrading enzyme DspB under the control of the Agr quorum-sensing system. We will be using existing BioBrick parts (the P2 promoter and AgrCA genes) as well as creating our own DspB Biobrick part. In addition, we plan to develop a new standard for working with bacteriophages that are 15-50kbp in length. <a href="https://2010.igem.org/Team:British_Columbia/Team">Learn more at our Project page!</a> |
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<div id="parts_box"> <center><a href="https://2010.igem.org/Team:British_Columbia/Parts"><img src="https://static.igem.org/mediawiki/2010/3/30/Partsbox.jpg" alt=""/></center></a> | <div id="parts_box"> <center><a href="https://2010.igem.org/Team:British_Columbia/Parts"><img src="https://static.igem.org/mediawiki/2010/3/30/Partsbox.jpg" alt=""/></center></a> | ||
| - | <p>Our | + | <p>Our new and characterized Biobrick part is the biofilm matrix-degrading enzyme DspB. We have also further characterized the promoters, P2 and Pcon in Staphylococcus aureus. <a href="https://2010.igem.org/Team:British_Columbia/Parts">For more details, visit our Parts page!</a> </p> </div> |
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<div id="modeling_box"> <center><a href="https://2010.igem.org/Team:British_Columbia/modeling"><img src="https://static.igem.org/mediawiki/2010/b/b6/Modelingbox.jpg" alt=""/></center> | <div id="modeling_box"> <center><a href="https://2010.igem.org/Team:British_Columbia/modeling"><img src="https://static.igem.org/mediawiki/2010/b/b6/Modelingbox.jpg" alt=""/></center> | ||
</a> | </a> | ||
| - | <p> | + | <p>We have developed a model that describes the population dynamics of the engineered bacteriophage and the affected biofilm by (1) writing a functional math model of the system, (2) providing numerical simulations that may predict the outcome of the system, and (3) using what we learn from the model to make hypotheses that we can test with our system. <a href="https://2010.igem.org/Team:British_Columbia/modeling">Run a simulation at our Modeling page!</a> |
| + | </p> </div> | ||
<div id="humanpractices_box"><center><a href="https://2010.igem.org/Team:British_Columbia/HumanPractices"><img src="https://static.igem.org/mediawiki/2010/e/eb/Hpbox.jpg" alt=""/></center> | <div id="humanpractices_box"><center><a href="https://2010.igem.org/Team:British_Columbia/HumanPractices"><img src="https://static.igem.org/mediawiki/2010/e/eb/Hpbox.jpg" alt=""/></center> | ||
</a> | </a> | ||
| - | <p> | + | <p>For our human practices project, we have compiled promoter maps depicting definitions of synthetic biology on the street, as well as creative works addressing different issues and ideas regarding the diverse aspects of synthetic biology and genetic engineering. You can also join in discussions about synthetic biology at our forum<a href="https://2010.igem.org/Team:British_Columbia/HumanPractices">What are you waiting for?</a> </p> |
| + | </div> | ||
<div id="notebook_box"> <center><a href="https://2010.igem.org/Team:British_Columbia/Notebook"><img src="https://static.igem.org/mediawiki/2010/e/ec/Notebookbox.jpg" alt=""/></center> | <div id="notebook_box"> <center><a href="https://2010.igem.org/Team:British_Columbia/Notebook"><img src="https://static.igem.org/mediawiki/2010/e/ec/Notebookbox.jpg" alt=""/></center> | ||
</a> | </a> | ||
| - | <p>Notebook...</p> </div> | + | <p>Every sub-team has its unique story of success and tragedy. What are important are the lessons learned, the trouble-shooting expertise gained, and the bonds of friendship formed. And of course, the victories! <a href="https://2010.igem.org/Team:British_Columbia/Notebook">Come trace our steps...</a> </p></div> |
<div class="clear"></div> | <div class="clear"></div> | ||
Revision as of 03:14, 18 September 2010
Blasting Away Biofilms
To disperse ''Staphylococcus aureus'' biofilms, our team is working to express an endogenous bacteriophage and biofilm matrix-degrading enzyme DspB under the control of the Agr quorum-sensing system.
Our Project PageAnd The Award Goes To...
Here's a list of the things we've accomplished according to iGEM judging and awards criteria. "I won and I get to scream and jump a little. But I got to go back to work tomorrow" - Benicio Del Toro, Best Supporting Actor.
See Our AccomplishmentsIt's Human!
Stop by our human practices section! What to see what people on the streets think about synthetic biology? We have quirky promoter maps, a live forum and a fabulous art gallery!
Talk Play Love
We are 9 undergraduate students, 2 graduate advisors and 2 faculty advisors from various disciplines including Pharmacology, Life Sciences, Physiology, Chemical and Biological Engineering, Materials Engineering, Engineering Physics and Computer Science.Come visit our Team page!
With the aim of dispersing Staphylococcus aureus biofilms, our team is working to express an endogenous bacteriophage and biofilm matrix-degrading enzyme DspB under the control of the Agr quorum-sensing system. We will be using existing BioBrick parts (the P2 promoter and AgrCA genes) as well as creating our own DspB Biobrick part. In addition, we plan to develop a new standard for working with bacteriophages that are 15-50kbp in length. Learn more at our Project page!
Our new and characterized Biobrick part is the biofilm matrix-degrading enzyme DspB. We have also further characterized the promoters, P2 and Pcon in Staphylococcus aureus. For more details, visit our Parts page!
We have developed a model that describes the population dynamics of the engineered bacteriophage and the affected biofilm by (1) writing a functional math model of the system, (2) providing numerical simulations that may predict the outcome of the system, and (3) using what we learn from the model to make hypotheses that we can test with our system. Run a simulation at our Modeling page!
For our human practices project, we have compiled promoter maps depicting definitions of synthetic biology on the street, as well as creative works addressing different issues and ideas regarding the diverse aspects of synthetic biology and genetic engineering. You can also join in discussions about synthetic biology at our forumWhat are you waiting for?
Every sub-team has its unique story of success and tragedy. What are important are the lessons learned, the trouble-shooting expertise gained, and the bonds of friendship formed. And of course, the victories! Come trace our steps...
The Team
Our team is composed of 9 undergraduate students, 2 graduate advisors and 2 faculty advisors. We are a diverse team from various disciplines including Pharmacology, Life Sciences, Physiology, Chemical and Biological Engineering, Materials Engineering, Engineering Physics and Computer Science.
iGEM
The International Genetically Engineered Machine competition (iGEM) is the premiere undergraduate Synthetic Biology competition. Student teams are given a set of biological parts from the Registry of Standard Biological Parts. Over the summer, the teams use these parts and new parts of their own to build biological systems and operate them in living cells. Through this experience, undergraduate students gain insight into the research process of searching out information and protocols to come up with their own novel project (not to mention all the trouble-shooting expertise gained!). Graduate student advisors also get a taste of what it feels like to be a principal investigator or lab technician in terms of providing for and guiding the undergraduate students. Finally, in November, hundreds of iGEM teams gather at MIT to compete at the annual Jamboree!
The contents and design of this wiki are published under the GNU Free Documentation License You are granted the right to copy and modify our work, but you must publish your work under the same type of license while recognizing the authors. Note: the design of this wiki originates from the Heidelberg 2009 iGEM Wiki.
