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Team:British Columbia/Project DspB
From 2010.igem.org
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| - | Dispersin B is an enzyme that degrades biofilms by catalyzing the hydrolysis of poly-ß-(1,6)-linked N-acetylglucosamine bond. </div> <!-- end SubWrapper --> | + | <h1><b>Introduction</b></h1> |
| + | Dispersin B (dspB) is an enzyme that degrades biofilms by catalyzing the hydrolysis of poly-ß-(1,6)-linked N-acetylglucosamine bond. These bonds exist as a polymer in the extracellular polymeric substance (EPS) as a polysaccharide adhesin; this adhesin is relevant in biofilm formation and integrity in both <i>Escherichia coli</i> and <i>Staphylococcus epidermidis</i>. According to Collins and Lu (reference paper), dspB effectively cleaves these bonds, thus affecting biofilm formation. Our goal is to isolate dspB from the host... | ||
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| + | <br><h1><b>Methods and Materials</b></h1></br> | ||
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| + | <br><h1><b>Expected Results</b></h1></br> | ||
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Revision as of 22:19, 28 September 2010
