Team:Freiburg Bioware

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<dt class="menu_button_center"><a href="https://2010.igem.org/Team:Freiburg_Bioware/Project">Project</a></dt>
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<dd class="first"><a href="https://2010.igem.org/Team:Freiburg_Bioware/Project/The_Adeno-associated Virus">Adeno-associated Virus</a></dd>
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<dt class="menu_button_right"><a href="https://2010.igem.org/Team:Freiburg_Bioware/Modelling">Modelling</a></dt>
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Revision as of 19:01, 8 October 2010

virus

In the last years the number of people affected by cancer increased significantly. About 25% cases of death are caused by malign tumors. Even though the industry is putting great efforts into developing effective strategies against cancer, innovative methods to fight tumors are needed. This year’s aim of Freiburg Bioware team 2010 is to create a universal virus construction kit which can be designed by submitted BioBricks. Our goal is to knockout the natural tropism of adeno-associated virus particles and to specifically target tumor cells by genetic engineering of the viral surface. The recombinant viruses will contain different genes coding for enzymes which convert harmless drugs into toxic molecules in targeted cell and kill the tumor cells. This approach will be a great advance in improving the growing field of personalized medicine.

Virus Construction Kit

Text

Project Summary


Klick for more
BioBricks

Modularisation and Modification of the viral tropismn and the effector function resulted in many different BioBricks.
Click here to explore them.
Biosafety

The aspect of biological safety was considered well and a risk assessment and security profile for the Adeno-associated Virus were created. To hear about this click here.
Cuckoo Clock Competition

In order to let the iGEM Community grow together we started the Cuckoo Clock Cometition. This Lab-Fun-Photo-Contest intends to give an impression from the work of other Teams. Click to become impressed.
Sponsors
Uni Freiburg Bioss kuk.lab
Roche Qiagen Zeiss Starlab
agilent Fermentas Hiss peqlab Geneart Eppendorf Gilson GATC ATG Biozym


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