Team:Washington

From 2010.igem.org

(Difference between revisions)
Line 28: Line 28:
<html>
<html>
<img src="https://static.igem.org/mediawiki/2010/0/09/Washington_testbanner.png" width="800" alt="21stCenturyAntibioticsBanner" usemap="#bannermap" />
<img src="https://static.igem.org/mediawiki/2010/0/09/Washington_testbanner.png" width="800" alt="21stCenturyAntibioticsBanner" usemap="#bannermap" />
-
==[[Image:Washington_testbanner.png|700px|center]]==
+
 
<map id="bannermap" name="bannermap">
<map id="bannermap" name="bannermap">

Revision as of 22:45, 13 October 2010


21stCenturyAntibioticsBanner Gram -


While vital to our quality of life, traditional antibiotics face the serious problems of widespread bacterial resistance and destruction of natural gut flora - problems which call for improved twenty-first century antibiotics. Using synthetic biology tools, we designed, built, and tested two new systems to fight infections by both broad types of bacteria - Gram-positive and Gram-negative. Our first project targets Bacillus anthracis, the Gram-positive pathogen that causes anthrax. We re-engineered an enzyme to remove the pathogen's protective coating, rendering it defenseless against the immune system. In our second project, we re-engineered and transplanted a protein secretion system capable of combating Gram-negative bacteria into E. coli. This system was designed to target Gram-negative pathogens in a modular and controllable fashion. These two systems are the vanguard of a new era of antibiotics using the power of nature harnessed with the tools of synthetic biology.



Gram(+) Therapeutic

Gram(-) Therapeutic