Team:UCL London

From 2010.igem.org

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<h2>PROJECT <strong>HYPOXON</strong></h2>
 
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<h3>Abstract</h3>
<h3>Abstract</h3>
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<p>Synthetic biology is now in a position to overcome many, hitherto, cumbersome and resource consuming manufacturing tasks. Society has now accepted the advent of such entities as recombinant insulin , monoclonal antibodies etc as essential for the future well being of human life. We can now use the bio engineered tools available to us to create systems which make manufacturing health or environmentally associated products simpler and more economical.</p>
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<p>UCL’s Biochemical engineering department has been at the forefront of biopharmaceutical manufacture for
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years. Extraordinary advances in the life sciences have great potential to
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improve our quality of life through better medicines and a cleaner environment.Our project aims to create “independent” cells, capable of self-induction into the production phase, without the
 +
introduction of any chemical into the closed system. By exploiting genetically
 +
modified E.coli to respond to hypoxia, we eliminate the need of IPTG
 +
induction. The functioning genetic circuit would be signalled by the production
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of a fluorescent red dye.
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Replacing the red dye gene with pharmaceutical
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protein promises higher yields and more consistent batches which is a step
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closer to providing cheaper healthcare to everyone.
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.</p>
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<h3>Team</h3>
<h3>Team</h3>
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<p>This is UCL's second year running and once again spearheading the project is the Biochemical Engineering department, collaborating with both the Biochemistry and Molecular Biology Departments. <br/><br/></html>[[Image:UCL_London_The_Team.jpg | 280px]]<html>
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<p>This is UCL's second year running and once again spearheading the project is the Biochemical Engineering department, collaborating with both the Biochemistry and Molecular Biology Departments. <br/><br/></html><html> <object width="320" height="320"><param name="movie" value="http://www.youtube.com/v/oYyF7gkQj1Y?fs=1&amp;hl=en_US&amp;color1=0x234900&amp;color2=0x4e9e00"></param><param name="allowFullScreen" value="true"></param><param name="allowscriptaccess" value="always"></param><embed src="http://www.youtube.com/v/oYyF7gkQj1Y?fs=1&amp;hl=en_US&amp;color1=0x234900&amp;color2=0x4e9e00" type="application/x-shockwave-flash" allowscriptaccess="always" allowfullscreen="true" width="290" height="320"></embed></object>
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<h3>Updates</h3>
<h3>Updates</h3>
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<p> Keep up to date with what's happening by following us on Twitter </p>
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<p> Keep up to date with what's happening by following us on Twitter
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</p>
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Revision as of 10:15, 20 September 2010

UCL IGEM 2010

RETURN TO IGEM 2010

Abstract

UCL’s Biochemical engineering department has been at the forefront of biopharmaceutical manufacture for years. Extraordinary advances in the life sciences have great potential to improve our quality of life through better medicines and a cleaner environment.Our project aims to create “independent” cells, capable of self-induction into the production phase, without the introduction of any chemical into the closed system. By exploiting genetically modified E.coli to respond to hypoxia, we eliminate the need of IPTG induction. The functioning genetic circuit would be signalled by the production of a fluorescent red dye. Replacing the red dye gene with pharmaceutical protein promises higher yields and more consistent batches which is a step closer to providing cheaper healthcare to everyone. .

Project Description

Team

This is UCL's second year running and once again spearheading the project is the Biochemical Engineering department, collaborating with both the Biochemistry and Molecular Biology Departments.

iGEM Team

Updates

Keep up to date with what's happening by following us on Twitter

iGEM Twitter

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