Team:Peking

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Revision as of 14:13, 7 October 2010

Students and Instructors

       Biosensor:
       Based on reverse engineering principles, we
   engineered our bacteria into valid bioreporters
   for Hg(II) in aquatic environment. Rational desi-
   -gn of genetic circuit topology was conducted to
   confer mercury sensor and regulator compone-
   -nts high efficiency and robustness. Additionally,
    a new approach based on the use of multiple
   bioreporter cell lines to control assay variations
   and to improve in field application ease was also
   developed.
                                           learn more

       Expansion:    MerR family TFs share a high homology at their
   metal binding domains, which implies that our strategies of bioreporter
   and bioabsorbent engineering might be applicable to other cases. Then our
    reverse engineering strategy was expanded to another common toxic heavy
    metal, lead (Pb) to prove the validness of our engineering strategy.learn more

@@ Line 8: / Line 8: @@
 &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Based on reverse engineering principles, we<br>
 &nbsp;&nbsp;&nbsp;engineered our bacteria into valid bioreporters <br>&nbsp;&nbsp;&nbsp;for Hg(II) in aquatic environment. Rational desi-<br>&nbsp;&nbsp;&nbsp;-gn of genetic circuit topology was conducted to <br>&nbsp;&nbsp;&nbsp;confer mercury sensor and regulator compone-<br>&nbsp;&nbsp;&nbsp;-nts high efficiency and robustness. Additionally,<br>&nbsp;&nbsp;&nbsp; a new approach based on the use of multiple <br>&nbsp;&nbsp;&nbsp;bioreporter cell lines to control assay variations <br>&nbsp;&nbsp;&nbsp;and to improve in field application ease was also <br>&nbsp;&nbsp;&nbsp;developed. <br>
-&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;<a href="https://2010.igem.org/Team:Peking/Project/Biosensor"><font size=4>---learn more</font></a></p>
+&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;<a href="https://2010.igem.org/Team:Peking/Project/Biosensor"><font size=4>learn more</font></a></p>
 <p><br>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;<font size=4>Expansion:</font>
-&nbsp;&nbsp;&nbsp;We noticed that MerR family TFs share a high ho-<br>&nbsp;&nbsp;&nbsp;-mology at their metal binding domains, which implies that our strategies of &nbsp;&nbsp;&nbsp;bioreporter and bioabsorbent engineering might be applicable to other cases. <br>&nbsp;&nbsp;&nbsp;Then our reverse engineering strategy was expanded to another common to-<br>&nbsp;&nbsp;&nbsp;-xic heavy metal, lead (Pb) to prove the validness of our engineering strategy.
+&nbsp;&nbsp;&nbsp;MerR family TFs share a high homology at their <br>&nbsp;&nbsp;&nbsp;metal binding domains, which implies that our strategies of bioreporter <br>&nbsp;&nbsp;&nbsp;and bioabsorbent engineering might be applicable to other cases. Then our<br>&nbsp;&nbsp;&nbsp; reverse engineering strategy was expanded to another common toxic heavy<br>&nbsp;&nbsp;&nbsp; metal, lead (Pb) to prove the validness of our engineering strategy.<a href="https://2010.igem.org/Team:Peking/Project/Expansion"><font size=2>learn more</font></a></p>

Team:Peking

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Revision as of 14:13, 7 October 2010

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