Team:TU Delft/team/history

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This is the third year the TU Delft is joining the iGEM competition. Considering the success of previous teams, the expectations are high.

TU Delft iGEM Team 2009 - BACTERIAL RELAY RACE

The teams aim was to build an improved cell to cell communication system. They were attempting to construct an E.coli strain which is capable of passing a GFP (Green Fluorescent Protein) signal through conjugation. This mechanism provides the ability of transferring genetic material between bacteria through direct cell to cell contact. A delayed self destructing mechanism caused the destruction of the genetic material of the donor cell after the transfer. The idea is comparable to a relay race.

Reward: Gold medal and award for ‘Best Information Processing Project’.

Read more on the TU Delft iGEM Team 2009 Wiki

TU Delft iGEM Team 2008 - ENGINEERING A BIOTHERMOMETER

The teams goal was to construct a temperature-sensing bacteria Escherichia coli that changes color at different temperatures. Such a thermometer can be applied e.g. as a temperature reporter system in large-scale fermentations, or as a temperature-inducible protein production system.

If the temperature exceeds a certain threshold, a sensitive RNA structure opens up and the ribosome (a molecular protein manufacturing machine) can bind to the RNA. This results in the production of a color compound - Farnesyl PyroPhosphate (FPP).

Reward: Golden medal and the trophy for the ‘Best Wiki’.

Read more on the TU Delft iGEM Team 2008 Wiki