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Team:St Andrews/project/safety
Our initial project aim was to express a single protein, CqsA, the cholera autoinducer synthase. CAI-1, the cholera autoinducer is known to cause a population wide shift to avirulence in virulent strains of V. cholerae. Although not all of the possible effects of CAI-1 on every organism are known, it is currently thought not to be of significant concern to researcher, public or environmental safety. Other quorum sensing parts we have used, most belonging to the Lux quorum sensing system are well understood and not expected to pose any hazards.
