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From 2010.igem.org

Modelling

Wiring Diagram

This is a outline of the regulatory topology of the concentration band-detect architecture.The different components and the way they interact with each other is represented similar to a electronic circuit.We use this as the starting point for building our model.First each of the components of our system was mathematically formulated. The components were then put together to form the whole system.

Model

Results

Code

odeIGEM03.m

 %lambda1 function file

function dX =odeIGEM02(t,X,P)

k1=P(1); k2=P(2); k3=P(3); k4=P(4); k5=P(5); k6=P(6); k7=P(7); k8=P(8); k9=P(9); k10=P(10); k11=P(11);

km1=P(12); km2=P(13); km3=P(14); km4=P(15); km5=P(16);

ahl=X(1); lam=X(2); ci=X(3); laci=X(4); gfp=X(5);

n1=1; n2=1; n3=1; n4=1; n5=2;

dlam=((k1*(ahl/km1)^n1)/(1+(ahl/km1)^n1))-k2*lam; dahl=0;%k10*ahl-k11*ahl; dci=((k3*(lam/km3)^n2)/(1+(lam/km3)^n2))-k4*ci; dlaci=(k5/(1+(ci/km3)^n3))+((k6*(lam/km4)^n4)/(1+(lam/km4)^n4))-k7*laci; dgfp=(k8/(1+(laci/km5)^n5))-k9*gfp;

dX=[dahl dlam dci dlaci dgfp]';