Team:St Andrews/project/modelling/model 1

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University of St Andrews iGEM 2010

Welcome!

University of St Andrews iGEM 2010

Our first year at iGEM!

Model 1: Single Cell without Feedback

Theory & Assumptions

The first method we attempted was to put the user in control of the change in HSL within the cell, and take any HSL produced and remove it from the system entirely. In this fashion a gradual increase in cell density was simulated by a linear “ramp up” of the HSL in the cell; a gradual decrease (presumably due to cell death) was simulated by a linear “ramp down” in HSL. The activation of the cell was measured by plotting the GFP concentration.

{Diagram showing model schematic}