Modeling Notebook

Welcome to the notebook of the modeling project. This notebook comprises the work on four sublanes: miBEAT, miRockdown, miBS designer and the model training set. Have fun!

Notebook

April

29.04.2010

• Meeting with Nao
  • Discuss about last years modeling approach
  • Problems to be avoided

Juli

13.06.2010

• Discussion about first model idea

21.06.2010

• Discussion about programming languages
  • Advantages of R, Perl and MatLab
  • Decision to use Perl and Matlab
  • Request for Matlab license

August

05.08.2010

• Activation of MatLab-Accounts

09.08.2010

• Meeting with Dr. König
  • Advantages and disadvantages of different modeling approaches
  • Possibility to use Neuronal Networks and Support Vektor Machines
    • http://en.wikipedia.org/wiki/Support_vector_machine

11.08.2010

• Activation of MatLab fuzzy logic toolbox

18.08.2010

• Meeting with Tim and Nao
  • Options to optimize a fuzzy logic model

22.08.2010

• Telemeeting with Stephen Krämer
  • Advantages and limitations of a fuzzy logic

September

07.09.2010

• Projectstart miBEAT
  • decision to create an interactive GUI on the wiki
  • creation of test model using javascript
• Activation of MatLab neuro net toolbox
  • Projectstart Neuronal Network model

08.09.2010

• Presentation of miBEAT project-concept on official team meeting

16-17.09.2010

• 6th Workshop on Computation of Biochemical Pathways and Genetic Networks
  • Parameter estimation in fuzzy/noisy systems
  • Global sensitivity analysis
  • New approaches to spatial modeling
  • Computation of microRNA regulatory network
• Discussion with Professor Sanghamitra Bandyopadhyay from the Machine Intelligence Unit of the Indian Statistical Institute in Kolkata
  • Advise to use a Rough set modeling approach
    • http://en.wikipedia.org/wiki/Rough_set

28.09.2010

• Project Start miRockdown
  • Developement of miRockdown concept
  • Decision on the use of the modified targetscan_50_context_scores–Algorithm for binding site evaluation