Team:NYU/Parts

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Revision as of 20:56, 18 August 2010

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We went in to the competition with certain goals for the parts we would make. Incorporating these goals with the 'Quality not Quantity' mantra, we decided to highlight certain areas of advancement that we believe future researchers would like to see in the registry.

1. To improve parts already in the registry by lessening the constrictions on their use and making them more adaptable.

  1a. 36bp LoxP site - the naturally-occuring substrate for the Cre recombinase, a 34bp LoxP site, is not a multiple of three. When using this part in transcribed regions, previous teams had to either add or take away bases from surrounding parts to keep their systems in frame (sometimes unsuccessfully). To get around this restriction, we designed and Biobricked a 36bp LoxP site that does not contain a stop codon or other troublesome sequences.

Tell us more about your project. Give us background. Use this is the abstract of your project. Be descriptive but concise (1-2 paragraphs)

File:NYU team.png

Your team picture

Team Example

Parts

New for iGEM 2010 is the groupparts tag. This tag will generate a table with all of the parts that your team adds to your team sandbox. Note that if you want to document a part you need to document it on the [http://partsregistry.org Registry], not on your team wiki.

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-|You can write a background of your team here.  Give us a background of your team, the members, etc.  Or tell us more about something of your choosing.
+|We went in to the competition with certain goals for the parts we would make. Incorporating these goals with the 'Quality not Quantity' mantra, we decided to highlight certain areas of advancement that we believe future researchers would like to see in the registry.
+. To improve parts already in the registry by lessening the constrictions on their use and making them more adaptable.
+a. 36bp LoxP site - the naturally-occuring substrate for the Cre recombinase, a 34bp LoxP site, is not a multiple of three. When using this part in transcribed regions, previous teams had to either add or take away bases from surrounding parts to keep their systems in frame (sometimes unsuccessfully). To get around this restriction, we designed and Biobricked a 36bp LoxP site that does not contain a stop codon or other troublesome sequences.
 |[[Image:NYU_logo.png|200px|right|frame]]
 |-