Team:SDU-Denmark/project-bc

From 2010.igem.org

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(Model results)
(The real system)
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"Attractant is assumed to be in excess and binding is assumed to be rapid". One of the most common receptor types to be modelled is the Tar receptor. This is not unexpected given that a large degree of the experimental literature has focused on the response of ''E. coli'' to aspartate which is detected by this receptor. Tar is also one of the most abundant receptors within the cytoplasmic membrane.<br>
"Attractant is assumed to be in excess and binding is assumed to be rapid". One of the most common receptor types to be modelled is the Tar receptor. This is not unexpected given that a large degree of the experimental literature has focused on the response of ''E. coli'' to aspartate which is detected by this receptor. Tar is also one of the most abundant receptors within the cytoplasmic membrane.<br>
In models which have focused on the adaptation and/or the phosphorylation cascade, receptors are commonly modelled as complexes consisting of MCP, CheW and CheA. This is justified by the tight association of CheW and CheA to the MCP receptors.<br>
In models which have focused on the adaptation and/or the phosphorylation cascade, receptors are commonly modelled as complexes consisting of MCP, CheW and CheA. This is justified by the tight association of CheW and CheA to the MCP receptors.<br>
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'''Descriptions of the motor bias''' <br>
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Descriptions of the motor bias, given the limited detail available on the interactions of both CheY-p and CheY with the cytoplasmic FliM end of flagella motors and that this interaction may be quite complex, it has been a common, simplifying assumption of a number of authors that the fraction of time a motor spends spinning counter-clockwise can be expressed in terms of CheY-p by a Hill function. Such reactions are based on experimental observations.
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Given the limited detail available on the interactions of both CheY-p and CheY with the cytoplasmic FliM end of flagella motors and that this interaction may be quite complex, it has been a common, simplifying assumption of a number of authors that the fraction of time a motor spends spinning counter-clockwise can be expressed in terms of CheY-p by a Hill function. Such reactions are based on experimental observations.
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=== Description of the model ===
=== Description of the model ===

Revision as of 16:18, 27 October 2010