Team:Northwestern/Project/Apoptosis

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Revision as of 16:28, 23 October 2010


Tech Institute
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Modeling Chassis Induction Chitin Apoptosis

We used the Apoptosis Cassette by Brown '08 iGEM team (K124017).

The bacteriophage cassette includes S105 protein (Holin), R protein (Endolysin), and Rz protein, all of which act in combination to lyse the bacteria.

Holin is a small membrane protein that produces holes in the membrane.

R is an endolysin that digests and cleaves the cell wall.

Rz protein, a periplasmic protein, through reasons that are not yet totally clear, carries out the final step of host lysis.

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