Team:Washington

From 2010.igem.org

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You are provided with this team page template with which to start the iGEM season.  You may choose to personalize it to fit your team but keep the same "look." Or you may choose to take your team wiki to a different level and design your own wiki.  You can find some examples <a href="https://2009.igem.org/Help:Template/Examples">HERE</a>.
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You <strong>MUST</strong> have a team description page, a project abstract, a complete project description, a lab notebook, and a safety page. PLEASE keep all of your pages within your teams namespace.
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<img src="https://static.igem.org/mediawiki/2010/b/be/Uwb.gif" alt="21stCenturyAntibioticsBanner" usemap="#bannermap" />
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<area shape="rect" alt="START button" title="Explore the Wiki" coords="384,258,447,279" href="https://2010.igem.org/Team:Washington/Gram_Negative"/>
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<area shape="rect" alt="Player 1 Gram(-)" title="Gram(-) Therapeutic" coords="343,281,493,300" href="https://2010.igem.org/Team:Washington/Gram_Negative"/>
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<area shape="rect" alt="Player 2 Gram(+)" title="Gram(+) Therapeutic" coords="343,302,492,320" href="https://2010.igem.org/Team:Washington/Gram_Positive"/>
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<area shape="poly" alt="Gram(+) Side" title="Gram(+) Therapeutic" coords="329,269,326,319,279,350,5,349,5,6,165,6,146,88,165,99,170,131,139,164,140,197,174,211" href="https://2010.igem.org/Team:Washington/Gram_Positive"/>
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<area shape="poly" alt="Gram(-) Side" title="Gram(-) Therapeutic" coords="507,269,509,322,546,350,793,350,793,3,689,4,673,23,681,76,660,116,648,168,655,197,623,248" href="https://2010.igem.org/Team:Washington/Gram_Negative"/>
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</map>
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<br />
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While vital to our quality of life, traditional antibiotics face the serious
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problems of widespread bacterial resistance and destruction of natural gut
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flora - problems which call for improved twenty-first century antibiotics.
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Using synthetic biology tools, we designed, built, and tested two new
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systems to fight infections by both broad types of bacteria - Gram-positive
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and Gram-negative.  Our first project targets ''Bacillus anthracis'', the
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Gram-positive pathogen that causes anthrax.  We re-engineered an enzyme to
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remove the pathogen's protective coating, rendering it defenseless against
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the immune system.  In our second project, we re-engineered and transplanted
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a protein secretion system capable of combating Gram-negative bacteria into
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''E. coli''.  This system was designed to target Gram-negative pathogens in a
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modular and controllable fashion.  These two systems are the vanguard of a
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new era of antibiotics using the power of nature harnessed with the tools of
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synthetic biology.
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<!---------------------------------------PAGE CONTENT GOES ABOVE THIS---------------------------------------->
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<div style="text-align:left">
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<center>
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'''[[Team:Washington/Gram_Negative|Gram(-) Therapeutic]]'''
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&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
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'''[[Team:Washington/Gram_Positive|Gram(+) Therapeutic]]'''
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</center>
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<div style="text-align:right">
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Subprojects:
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</div>
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[[Team:Washington/Warrior_Bacteria|Warrior Bacteria]]
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[[Team:Washington/Registry_Tools|Registry Tools]]
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[[Team:Washington/Anthrax_Decapsulation|Anthrax Decapsulation]]
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|[[Image:Washington_logo.png|200px|right|frame]]
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{| style="color:#1b2c8a;background-color:#0c6;" cellpadding="3" cellspacing="1" border="1" bordercolor="#fff" width="62%" align="center"
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{{Template:Team:Washington/Templates/Footer}}
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!align="center"|[[Team:Washington|Home]]
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!align="center"|[[Team:Washington/Team|Team]]
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!align="center"|[https://igem.org/Team.cgi?year=2010&team_name=Washington Official Team Profile]
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!align="center"|[[Team:Washington/Project|Project]]
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!align="center"|[[Team:Washington/Parts|Parts Submitted to the Registry]]
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!align="center"|[[Team:Washington/Modeling|Modeling]]
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!align="center"|[[Team:Washington/Notebook|Notebook]]
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!align="center"|[[Team:Washington/Safety|Safety]]
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|}
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Latest revision as of 01:14, 28 October 2010

21stCenturyAntibioticsBanner START button Player 1 Gram(-) Player 2 Gram(+) Gram(+) Side Gram(-) Side


While vital to our quality of life, traditional antibiotics face the serious problems of widespread bacterial resistance and destruction of natural gut flora - problems which call for improved twenty-first century antibiotics. Using synthetic biology tools, we designed, built, and tested two new systems to fight infections by both broad types of bacteria - Gram-positive and Gram-negative. Our first project targets Bacillus anthracis, the Gram-positive pathogen that causes anthrax. We re-engineered an enzyme to remove the pathogen's protective coating, rendering it defenseless against the immune system. In our second project, we re-engineered and transplanted a protein secretion system capable of combating Gram-negative bacteria into E. coli. This system was designed to target Gram-negative pathogens in a modular and controllable fashion. These two systems are the vanguard of a new era of antibiotics using the power of nature harnessed with the tools of synthetic biology.


Gram(-) Therapeutic                  Gram(+) Therapeutic


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