Team:KAIST-Korea/Notebook/Diary/April
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<html><a href="https://2010.igem.org/Team:KAIST-Korea/Notebook/Diary/April"><img src="https://static.igem.org/mediawiki/2010/e/e1/April.jpg" width=100></a></html> | <html><a href="https://2010.igem.org/Team:KAIST-Korea/Notebook/Diary/April"><img src="https://static.igem.org/mediawiki/2010/e/e1/April.jpg" width=100></a></html> | ||
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<html><a href="https://2010.igem.org/Team:KAIST-Korea/Notebook/Diary/May"><img src="https://static.igem.org/mediawiki/2010/6/6d/5%EC%9B%94.jpg | <html><a href="https://2010.igem.org/Team:KAIST-Korea/Notebook/Diary/May"><img src="https://static.igem.org/mediawiki/2010/6/6d/5%EC%9B%94.jpg | ||
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<html><a href="https://2010.igem.org/Team:KAIST-Korea/Notebook/Diary/June"><img src=" https://static.igem.org/mediawiki/2010/3/31/6%EC%9B%94.jpg" width=100></a></html> | <html><a href="https://2010.igem.org/Team:KAIST-Korea/Notebook/Diary/June"><img src=" https://static.igem.org/mediawiki/2010/3/31/6%EC%9B%94.jpg" width=100></a></html> | ||
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<html><a href="https://2010.igem.org/Team:KAIST-Korea/Notebook/Diary/July"><img src="https://static.igem.org/mediawiki/2010/4/49/7%EC%9B%94.jpg | <html><a href="https://2010.igem.org/Team:KAIST-Korea/Notebook/Diary/July"><img src="https://static.igem.org/mediawiki/2010/4/49/7%EC%9B%94.jpg | ||
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<html><a href="https://2010.igem.org/Team:KAIST-Korea/Notebook/Diary/August"><img src="https://static.igem.org/mediawiki/2010/5/55/8%EC%9B%94.jpg | <html><a href="https://2010.igem.org/Team:KAIST-Korea/Notebook/Diary/August"><img src="https://static.igem.org/mediawiki/2010/5/55/8%EC%9B%94.jpg | ||
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<html><a href="https://2010.igem.org/Team:KAIST-Korea/Notebook/Diary/September"><img src="https://static.igem.org/mediawiki/2010/0/02/9%EC%9B%94.jpg | <html><a href="https://2010.igem.org/Team:KAIST-Korea/Notebook/Diary/September"><img src="https://static.igem.org/mediawiki/2010/0/02/9%EC%9B%94.jpg | ||
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<html><a href="https://2010.igem.org/Team:KAIST-Korea/Notebook/Diary/October"><img src="https://static.igem.org/mediawiki/2010/9/91/10%EC%9B%94.jpg | <html><a href="https://2010.igem.org/Team:KAIST-Korea/Notebook/Diary/October"><img src="https://static.igem.org/mediawiki/2010/9/91/10%EC%9B%94.jpg | ||
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<html><a href="https://2010.igem.org/Team:KAIST-Korea/Notebook/Diary/November"><img src="https://static.igem.org/mediawiki/2010/3/35/11%EC%9B%94.jpg | <html><a href="https://2010.igem.org/Team:KAIST-Korea/Notebook/Diary/November"><img src="https://static.igem.org/mediawiki/2010/3/35/11%EC%9B%94.jpg | ||
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Alcanivorax Borkumensis is the bacteria that releases enzyme that can decompose oil. And we can design something like insulin producing system to solve oil spilling problems in ocean. | Alcanivorax Borkumensis is the bacteria that releases enzyme that can decompose oil. And we can design something like insulin producing system to solve oil spilling problems in ocean. | ||
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- | Problem: | + | Problem: Similar system already exists. <br><br> |
<span style=font-size:15px> <b> Idea 2 </b> </span> | <span style=font-size:15px> <b> Idea 2 </b> </span> | ||
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<span style=font-size:15px> <b> Idea 3 </b> </span> | <span style=font-size:15px> <b> Idea 3 </b> </span> | ||
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- | + | We can make new bacteria that imitate photosynthesis. We can extract only chloroplast part of photosynthesizing organisms – for instance, plants – or use cyanobacteria to make some kind of energy generating building parts: paint (cyanobacteria is the photosynthesizing bacteria). In case of stromatolite, we can use it as building structure. | |
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- | + | Problem: We have to make e.coli to be as big as chloroplast. Also, since it physically surrounds building, there is problem when there is no sun or in bad weather. When it rains it could mess up sewage system.<br><br> | |
- | We have to make e.coli to be as big as chloroplast. | + | |
<span style=font-size:15px> <b> Idea 4 </b> </span> | <span style=font-size:15px> <b> Idea 4 </b> </span> | ||
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- | Making a NAND gate with E.coli. We can use 0/1 logic with some kind of chemicals as input and output. And we can make | + | Making a NAND gate with E.coli. We can use 0/1 logic with some kind of chemicals as input and output. And, we can make intermediate phase to prevent unintentional mix up of input and output chemical. We are thinking of lactose tryptophan as input. Since Stanford has done some basic works on this, we can take that advantage. If we make this, we can make a flip flop which is the basic component of memory system. |
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- | If we use chemical as input and output we have to control chemical level. We have to make a system threshold to differentiate 0 or 1.<br><br> | + | Problem: If we use chemical as input and output we have to control chemical level. We have to make a system threshold to differentiate 0 or 1.<br><br> |
<span style=font-size:15px> <b> Idea 5 </b> </span> | <span style=font-size:15px> <b> Idea 5 </b> </span> | ||
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- | + | Making a photographer with yeast. We are making a photographer with RGB cone cells and fluorescence. There already exists a study on cone cell receptors. We can make RGB ratio as 40:20:1 like human retina. Film would be yeast. Therefore, it can grow infinitely. | |
- | + | <br> | |
- | + | Problem: Film cannot be copied. We have to be careful not to get light on film after taking a picture. It is not a matter of sensing but processing images in brain. Therefore, we are not sure of the feasibility. <br><br> | |
<span style=font-size:15px> <b> Idea 6 </b> </span> | <span style=font-size:15px> <b> Idea 6 </b> </span> | ||
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- | + | Copyteria; we make a bacterium that copies. We put dye or degrader in e.coli. It would be important to design a threshold. We have to make bacteria to be alive during the coping process and lose its color after the coping process. So we are making bacteria ink. | |
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- | + | Problem: we don't know the threshold, and, even if it works, Copyteria have to perform in a dark room. Since the idea is to get an image from a reflected image, we don't know how this reflected image would be copied: too many unknown variables.<br><br><br> | |
== April 30 == | == April 30 == | ||
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<span style=font-size:15px> <b> Idea 1 </b> </span> | <span style=font-size:15px> <b> Idea 1 </b> </span> | ||
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- | + | Leeches prevent blood to from coagulating. There is already a product derived from vampire bat. If we use similar system to make anti-coagulant using bacteria, it may solve localization problems related with conventional anti-coagulants. | |
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<span style=font-size:15px> <b> Idea 2 </b> </span> | <span style=font-size:15px> <b> Idea 2 </b> </span> | ||
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- | Using bacteria we could make a carrier that | + | Using bacteria, we could make a carrier that has chemicals that can cure cancer with targeting-capability. |
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<span style=font-size:15px> <b> Idea 3 </b> </span> | <span style=font-size:15px> <b> Idea 3 </b> </span> | ||
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- | Using magnetosome we could make a system that can detect magnetic field like other iGEM | + | Using magnetosome, we could make a system that can detect magnetic field just like other iGEM teams made product that detect toxicity. |
- | + | <br> | |
- | + | Problem: It would be reacting passively to the magnetic field, so it is not appropriate for detection. | |
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<span style=font-size:15px> <b> Idea 4 </b> </span> | <span style=font-size:15px> <b> Idea 4 </b> </span> | ||
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- | + | We want to make an oscillator. There is a memory network used in remembering. We can combine it with telomere. We can manipulate time using this protocol. | |
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<span style=font-size:15px> <b> Idea 5 </b> </span> | <span style=font-size:15px> <b> Idea 5 </b> </span> | ||
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- | Using vibration maybe we can make bacteria make sound. | + | Using vibration, maybe we can make bacteria that make sound. |
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<span style=font-size:15px> <b> Idea 6 </b> </span> | <span style=font-size:15px> <b> Idea 6 </b> </span> | ||
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- | If we can make a NAND gate, we can make a calculator. Maybe we can make a compare system. | + | If we can make a NAND gate, we can make a calculator. Maybe we can make a compare system. We can use this for comparing concentration difference, and we may use it in a cell system that we will build. |
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<span style=font-size:15px> <b> Idea 7 </b> </span> | <span style=font-size:15px> <b> Idea 7 </b> </span> | ||
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- | We can put antigen in mosquitoes | + | We can put antigen in mosquitoes’ saliva, and the mosquitoes would naturally put antigens in people to build them immunity against malaria. Since malaria mosquitoes are active only during night, we can use mosquitoes that are active during day. |
- | + | <br> | |
- | It could make a problem if accidently inject too much antigens | + | Problem: It could make a problem if mosquitoes accidently inject too much antigens? |
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<span style=font-size:15px> <b> Idea 8 </b> </span> | <span style=font-size:15px> <b> Idea 8 </b> </span> | ||
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- | In case of DDS packing is the problem. And we can use vesicle system for packing. | + | In case of DDS, packing is the problem. And we can use vesicle system for packing. |
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<span style=font-size:15px> <b> Idea 9 </b> </span> | <span style=font-size:15px> <b> Idea 9 </b> </span> | ||
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- | Using Na+ pump | + | Using Na+ pump, we can make electricity: many related studies exist. There are microorganisms, which circulate electron. If we use this system in bacteria we might make battery. |
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<span style=font-size:15px> <b> Idea 10 </b> </span> | <span style=font-size:15px> <b> Idea 10 </b> </span> | ||
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- | + | RBCs can trap virus because virus can't replicate in RBCs. Such system can only delay infection; it is no cure. Therefore, it is not perfect system. However, many possible applications remain; we can use it for rabies because the infection proceeds faster than healing process. | |
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<span style=font-size:15px> <b> Idea 11 </b> </span> | <span style=font-size:15px> <b> Idea 11 </b> </span> | ||
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- | There are many steps in mammalian cell replication | + | There are many steps in mammalian cell replication. If we make a mammalian cell replicable in vitro, it would be very convenient for researchers. |
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<span style=font-size:17px> <b> Idea Sum-up </b> </span> | <span style=font-size:17px> <b> Idea Sum-up </b> </span> | ||
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- | + | We can work on mammalian cell replication tool or DDS that works on respiratory system. So, we decided to dig more on those topics. | |
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Latest revision as of 05:13, 17 October 2010
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