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<table width=70%><tr><td><div id="bodybaby">the bacterial uv toggle</div></td> | <table width=70%><tr><td><div id="bodybaby">the bacterial uv toggle</div></td> | ||
| - | <tr><td> In the beginning, there was a UV Toggle | + | <tr><td> In the beginning, there was a UV Toggle (<a href="http://www.nature.com/nature/journal/v403/n6767/abs/403339a0.html">Collins, 2000</a>). <br> The 2010 MIT iGEM team saw that it was good, and decided to implement the Collins toggle in E.coli to create cells with bistable phenotypes. There was a pattern of fluorescence or polymer formation induced by patterned UV exposure -- the first image.<br> <a href="https://static.igem.org/mediawiki/2010/c/cc/UV_Circuit1.jpg" class="thickbox" title="Bacterial UV Toggle for controlling phage polymerization"><img src="https://static.igem.org/mediawiki/2010/c/cc/UV_Circuit1.jpg" height=200px></a> |
<div style="display: block; background-color: #boc4de; width: 300px; float: right; font-size: small;"><a href="https://static.igem.org/mediawiki/2010/e/eb/Igem_uv_prelim.png" class="thickbox" title="Power Modulation using the Low Power Toggle and cells that fluoresce red with UV induction."><img src="https://static.igem.org/mediawiki/2010/e/eb/Igem_uv_prelim.png" width=300px></a><br>Here we see cells controlled by the Low Power Toggle. The cells fluoresce red with UV induction, but at higher UV levels cell death can be seen in the green field.</div> | <div style="display: block; background-color: #boc4de; width: 300px; float: right; font-size: small;"><a href="https://static.igem.org/mediawiki/2010/e/eb/Igem_uv_prelim.png" class="thickbox" title="Power Modulation using the Low Power Toggle and cells that fluoresce red with UV induction."><img src="https://static.igem.org/mediawiki/2010/e/eb/Igem_uv_prelim.png" width=300px></a><br>Here we see cells controlled by the Low Power Toggle. The cells fluoresce red with UV induction, but at higher UV levels cell death can be seen in the green field.</div> | ||
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Revision as of 20:42, 9 October 2010
iGEM 2010
Undergraduates Instructors Advisors Fun Sponsors
Overview Toggle Phage Mammalian Summary Acknowledgements
Materials & Methods Biosafety Journal Club
the bacterial uv toggle |
| In the beginning, there was a UV Toggle (Collins, 2000). The 2010 MIT iGEM team saw that it was good, and decided to implement the Collins toggle in E.coli to create cells with bistable phenotypes. There was a pattern of fluorescence or polymer formation induced by patterned UV exposure -- the first image. 
 Here we see cells controlled by the Low Power Toggle. The cells fluoresce red with UV induction, but at higher UV levels cell death can be seen in the green field. |
