Team:Imperial College London/Achievements

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|Had a fantastic summer, learnt loads and formed new friendships.
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|Had a fantastic summer, '''learned loads''' and formed '''new friendships'''.
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|Run a series of Synthetic Biology School Workshops, and provided tools for others to follow suit.
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|Tackled the problem of '''Neglected Tropical Diseases''' for the '''first time''' in the iGEM competition.
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|Submitted 23 documented parts to the registry.
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|Submitted '''[https://2010.igem.org/Team:Imperial_College_London/Parts 23 documented parts]''' to the registry.
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|Contributed the PyrD and AmyE vectors to the registry and have used Dif excision to remove antibiotic resistance genes from our cassettes.
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|Developed '''integration vectors''' for BioBrick parts and devices which allow integration of cassettes into the ''B. subtilis'' genome, resulting in '''disruption of essential genes'''. Dif excision allows '''removal of antibiotic resistance genes''' from our cassettes.  
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|Tackled the problem of '''Neglected Tropical Diseases''' for the '''first time''' in the iGEM competition.
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|Extensively '''characterized the existing BioBrick part, 'XylE reporter gene with RBS' ''' (BBa_J33204).
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|Extensively characterized the existing BioBrick part, 'XylE reporter gene with RBS (BBa_J33204).
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|Submitted '''new coding parts''' such as the histidine kinase ComD (K316015).
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|Shown that the '''novel engineered BioBrick part''', GFP-XylE (BBa_K316007) works as expected.
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|Submitted '''new coding regions''' for the histidine kinase ComD (K316015) and its response regulator ComE (K316016).
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|Designed a '''software tool''' for protease detection and protein presentation on the surface of ''B. subtilis''.
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|Submitted a very useful, modular and '''natural BioBrick Part''', the LytC cell wall binding domain (CWBD).
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|Submitted a very useful, modular and natural BioBrick Part, the LytC CWBD.
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|Designed a '''[https://2010.igem.org/Team:Imperial_College_London/Software_Tool software tool]''' for protease detection and protein presentation on the surface of ''B. subtilis'' using the LytC CWBD.
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|Shown that the novel engineered BioBrick part, GFP-XylE (BBa_K316007) works as expected.
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|Explored the [https://2010.igem.org/Team:Imperial_College_London/Human_Practices Human Practices] aspects of our project including the '''ethical, social, environmental, economic and political implications''' of our detection kit including the setting in which it would be implemented.
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|Developed integration vectors for BioBrick parts and devices which can allow integration of various cassettes into the ''B. subtilis'' genome, allowing disription of essential genes.
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|Based our specifications on '''[https://2010.igem.org/Team:Imperial_College_London/Modelling modelling]''' and '''[https://2010.igem.org/Team:Imperial_College_London/Human_Practices human practices]'''.
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|Based our specifications on '''modelling''' and '''human practices'''.
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|Managed to get loads of '''[https://2010.igem.org/Team:Imperial_College_London/Results experimental results]'''!
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|Explored the https://2010.igem.org/Team:Imperial_College_London/Human_Practices Human Practices] aspects of our project including the ethical, social, environmental, economic and political implications of our detection kit including the setting in which it would be
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|Completed the whole iteration through the '''engineering design cycle for each module''' of our system.
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|Managed to get loads of [https://2010.igem.org/Team:Imperial_College_London/Results experimental results]!
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|Explored the '''production and implementation considerations''' that we thought might be important in the manufacture of Parasight as a viable product.
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|Helped other iGEM teams (including Warsaw, UNAM-Mexico and METU-Turkey) by completing their surveys.
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|Investigated the '''[https://2010.igem.org/Team:Imperial_College_London/Results safety implications]''' of the project as a whole.
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|Based our design specifications on computer modelling, which enabled us to decide which ideas should be implemented in our design.
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|Run a series of '''Synthetic Biology School Workshops''', and provided a '''toolkit for others teams''' follow suit.
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  <img style="width:30px;" src="https://static.igem.org/mediawiki/2010/5/56/ICtickicon.png" />
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|Completed the whole iteration through the engineering cycle for each module of our system.
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|'''Helped other iGEM teams''' (including Warsaw, UNAM-Mexico and METU-Turkey) by completing their surveys.
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<img style="width:30px;" src="https://static.igem.org/mediawiki/2010/5/56/ICtickicon.png" />
 
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|Explored the Manufacturing Considerations that we thought important to manufacture Parasight as a viable product.
 
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<img style="width:30px;" src="https://static.igem.org/mediawiki/2010/5/56/ICtickicon.png" />
 
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|Investigated the safety implications of the project as a whole.
 
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Latest revision as of 03:17, 28 October 2010

Achievements
We have:
Had a fantastic summer, learned loads and formed new friendships.
Tackled the problem of Neglected Tropical Diseases for the first time in the iGEM competition.
Submitted 23 documented parts to the registry.
Developed integration vectors for BioBrick parts and devices which allow integration of cassettes into the B. subtilis genome, resulting in disruption of essential genes. Dif excision allows removal of antibiotic resistance genes from our cassettes.
Extensively characterized the existing BioBrick part, 'XylE reporter gene with RBS' (BBa_J33204).
Submitted new coding parts such as the histidine kinase ComD (K316015).
Shown that the novel engineered BioBrick part, GFP-XylE (BBa_K316007) works as expected.
Submitted a very useful, modular and natural BioBrick Part, the LytC cell wall binding domain (CWBD).
Designed a software tool for protease detection and protein presentation on the surface of B. subtilis using the LytC CWBD.
Explored the Human Practices aspects of our project including the ethical, social, environmental, economic and political implications of our detection kit including the setting in which it would be implemented.
Based our specifications on modelling and human practices.
Managed to get loads of experimental results!
Completed the whole iteration through the engineering design cycle for each module of our system.
Explored the production and implementation considerations that we thought might be important in the manufacture of Parasight as a viable product.
Investigated the safety implications of the project as a whole.
Run a series of Synthetic Biology School Workshops, and provided a toolkit for others teams follow suit.
Helped other iGEM teams (including Warsaw, UNAM-Mexico and METU-Turkey) by completing their surveys.