Team:MIT summary
From 2010.igem.org
(Difference between revisions)
(New page: {{CM_css}} <html> <head> <style> #topnav li.academics a { background-color: #2e2e91; } #topnav li.academics ul { display: block; } #content { background-image: url('http://2010.igem.o...) |
|||
(18 intermediate revisions not shown) | |||
Line 12: | Line 12: | ||
#content { | #content { | ||
background-image: url('https://static.igem.org/mediawiki/2010/a/ae/Peacock_Drop.jpg'); | background-image: url('https://static.igem.org/mediawiki/2010/a/ae/Peacock_Drop.jpg'); | ||
+ | background-attachment: fixed; | ||
} | } | ||
</style> | </style> | ||
Line 24: | Line 25: | ||
<ul> | <ul> | ||
<li><a href="https://2010.igem.org/Team:MIT_toggle">Overview</a></li> | <li><a href="https://2010.igem.org/Team:MIT_toggle">Overview</a></li> | ||
+ | <li><a href="https://2010.igem.org/Team:MIT_tmodel">Modelling</a></li> | ||
<li><a href="https://2010.igem.org/Team:MIT_tconst">Toggle Construction</a></li> | <li><a href="https://2010.igem.org/Team:MIT_tconst">Toggle Construction</a></li> | ||
- | <li><a href=" | + | <li><a href="https://2010.igem.org/Team:MIT_tchara">Characterization</a></li> |
</ul> | </ul> | ||
</dd> | </dd> | ||
Line 43: | Line 45: | ||
<dt><b>Mammalian</b></dt> | <dt><b>Mammalian</b></dt> | ||
+ | |||
<dd> | <dd> | ||
<ul> | <ul> | ||
- | <li><a href=" | + | <li><a href="https://2010.igem.org/Team:MIT_mammalian">Overview</a></li> |
- | <li><a href=" | + | <li><a href="https://2010.igem.org/Team:MIT_mammalian_Standard">New Mammalian Standard </a></li> |
- | <li><a href=" | + | <li><a href="https://2010.igem.org/Team:MIT_mammalian_Circuit">Circuit Design</a></li> |
+ | <li><a href="https://2010.igem.org/Team:MIT_mammalian_Mechanosensation"> Mechanosensation</a></li> | ||
+ | <li><a href="https://2010.igem.org/Team:MIT_mammalian_Bone"> Bone Formation</a></li> | ||
+ | <li><a href="https://2010.igem.org/Team:MIT_mammalian_Switch"> Synthetic Switch</a></li> | ||
</ul> | </ul> | ||
Line 57: | Line 63: | ||
<div id="unique" style="padding:0px; font-size: 14px; border: 1px solid black; margin:0px; background-color:transparent;"> | <div id="unique" style="padding:0px; font-size: 14px; border: 1px solid black; margin:0px; background-color:transparent;"> | ||
<table width=650px style="background-color: white; margin-top:5px; padding: 10px;"><tr><td> | <table width=650px style="background-color: white; margin-top:5px; padding: 10px;"><tr><td> | ||
- | <div class="bodybaby"> | + | <div class="bodybaby">summary</div></td> |
<tr><td><br> | <tr><td><br> | ||
- | |||
- | |||
- | |||
- | |||
- | |||
- | |||
- | |||
- | |||
- | |||
- | |||
- | |||
- | + | <img style="float: left; padding: 10px" src="https://static.igem.org/mediawiki/2010/0/02/Overview-illustration_03.png" width=600px><br> | |
+ | Living materials are powerful organic tools; they’re defined by their ability to adapt, to grow, to respond. Your skeleton becomes denser in regions of higher pressure; imagine a skyscraper or a bridge built of material with same capabilites!! <br><br> | ||
- | + | When summer began, we imagined creating tiny biomaterial factories. We wanted to touch a plate of cells and watch them turn to bone. We envisioned a bacterial colony, sensing a pattern of radiation and synthesizing a 3D biomaterial composed only of interlinked particles of virus.<br><Br> | |
- | We have a working synthetic circuit, capable of turning a small sensory pulse into a long term differentiation program. | + | <b>So what have we accomplished towards these goals?</b><br> |
+ | <ul><li> We have a working synthetic circuit, capable of sensing radiation in bacterial cells, one that we’ve tinkered with to minimize cell death. | ||
+ | <img style="float: left; padding: 10px" src="https://static.igem.org/mediawiki/2010/1/18/Screen_shot_2010-10-27_at_11.43.36_AM.png" width=600px> | ||
+ | </li> | ||
+ | <li>We’ve infected bacteria with modified phage to create ‘hairy’ cells, and we’ve added pairs of linkers to phage proteins (via genetic fusion) that could allow them to polymerize.</li> | ||
+ | <li>In the mammalian system, we have cloned mechano-sensitive promoters and tested them in microfluidic devices.</li> | ||
+ | <li>We’ve induced stem cells to differentiate into bone.<br> | ||
+ | <img style="float: left; padding: 10px" src="https://static.igem.org/mediawiki/2010/1/19/MammalianMaterial2.gif" width = 600px></li><br> | ||
+ | <li>We have a working synthetic circuit, capable of turning a small sensory pulse into a long term differentiation program. </li></ul><br> | ||
This project is just the beginning; we’ve created the groundwork for a toolkit that anybody can use, one that will allow us to link sensory input to biomaterial creation. The system that we’ve built is meant to be expanded on, and our results can act as the basis for future exploration into of world of 3D organic material creation. </td> | This project is just the beginning; we’ve created the groundwork for a toolkit that anybody can use, one that will allow us to link sensory input to biomaterial creation. The system that we’ve built is meant to be expanded on, and our results can act as the basis for future exploration into of world of 3D organic material creation. </td> |
Latest revision as of 22:45, 27 October 2010
summary |
![]() Living materials are powerful organic tools; they’re defined by their ability to adapt, to grow, to respond. Your skeleton becomes denser in regions of higher pressure; imagine a skyscraper or a bridge built of material with same capabilites!! When summer began, we imagined creating tiny biomaterial factories. We wanted to touch a plate of cells and watch them turn to bone. We envisioned a bacterial colony, sensing a pattern of radiation and synthesizing a 3D biomaterial composed only of interlinked particles of virus. So what have we accomplished towards these goals?
This project is just the beginning; we’ve created the groundwork for a toolkit that anybody can use, one that will allow us to link sensory input to biomaterial creation. The system that we’ve built is meant to be expanded on, and our results can act as the basis for future exploration into of world of 3D organic material creation. |