Team:Brown/Modeling

From 2010.igem.org

(Difference between revisions)
(Modeling the Quad-state)
(Light-Pattern Controlled Circuit)
 
(27 intermediate revisions not shown)
Line 1: Line 1:
-
{| style="color:#1b2c8a;background-color:#0c6;" cellpadding="3" cellspacing="1" border="1" bordercolor="#fff" width="62%" align="center"
+
{{:Team:Brown/templates/header}}
-
!align="center"|[[Team:Brown|Home]]
+
-
!align="center"|[[Team:Brown/Team|Team]]
+
-
!align="center"|[https://igem.org/Team.cgi?year=2010&team_name=Brown Official Team Profile]
+
-
!align="center"|[[Team:Brown/Project|Project]]
+
-
!align="center"|[[Team:Brown/Parts|Parts Submitted to the Registry]]
+
-
!align="center"|[[Team:Brown/Modeling|Modeling]]
+
-
!align="center"|[[Team:Brown/Notebook|Notebook]]
+
-
!align="center"|[[Team:Brown/Safety|Safety]]
+
-
|}
+
-
==Modeling the Quad-state==
+
=Modeling=
-
<html>
+
[[Image:Jensmile.jpg|left|300px]]
-
<embed src="https://static.igem.org/mediawiki/2010/c/c8/Circuit3.swf" quality="high" bgcolor="#ffffff" width="640" height="600" name="mymoviename" align="" type="application/x-shockwave-flash" pluginspage="http://www.macromedia.com/go/getflashplayer">
+
===Modeling the Quad-state Circuit===
-
</html>
+
-
The above model demonstrates the interaction between parts that make up the quad-state system. S1, S2, S3, and S4 are reporter molecules that represent each state, and could be replaced by any desired protein (for activation of other pathways, production of enzymes for biosynthesis, etc).
+
Because our light circuit consists of four distinct steady states, we choose to model our system initially using a deterministic system. In this section, we will discuss the following:
 +
# The [[Team:Brown/Modeling/ODEs | system of ordinary differential equations]] that we formulated to model our system and the biological basis for each
 +
# The [[Team:Brown/Modeling/Parameters | parameters]] we used in our model and the basis for them
 +
# The [[Team:Brown/Modeling/Results| results]] of our model and the conclusions drawn from them
 +
# The [[Team:Brown/Modeling/Light device| illumination device ]] we designed to induce the state switching of our circuit.

Latest revision as of 18:19, 27 October 2010

Modeling

Jensmile.jpg

Modeling the Quad-state Circuit

Because our light circuit consists of four distinct steady states, we choose to model our system initially using a deterministic system. In this section, we will discuss the following:

  1. The system of ordinary differential equations that we formulated to model our system and the biological basis for each
  2. The parameters we used in our model and the basis for them
  3. The results of our model and the conclusions drawn from them
  4. The illumination device we designed to induce the state switching of our circuit.