Team:Newcastle/Meetings/24 February 2010
From 2010.igem.org
(Difference between revisions)
Line 10: | Line 10: | ||
*iGEM 2010 Team Newcastle Registered | *iGEM 2010 Team Newcastle Registered | ||
*Final Date for Jamboree 5-8th Nov? | *Final Date for Jamboree 5-8th Nov? | ||
+ | |||
==== SHORTLIST SO FAR: ==== | ==== SHORTLIST SO FAR: ==== | ||
'''Project ideas''' – team members assigned to look into this projects | '''Project ideas''' – team members assigned to look into this projects | ||
- | |||
TOP FIVE | TOP FIVE | ||
:[1] '''Computing DNA''' - Rachel, Zoltan, Steven | :[1] '''Computing DNA''' - Rachel, Zoltan, Steven | ||
Line 20: | Line 20: | ||
:[4] '''Headlice''' - Richard, Janetta,Phil | :[4] '''Headlice''' - Richard, Janetta,Phil | ||
:[5] '''Linearising DNA''' - Richard, Phil, Zoltan | :[5] '''Linearising DNA''' - Richard, Phil, Zoltan | ||
- | |||
- | |||
Possible other projects | Possible other projects | ||
:[A] '''Diabetes''' - Da, Younus and Harsh | :[A] '''Diabetes''' - Da, Younus and Harsh | ||
:[B] '''French Flag''' - Steven and Zoltan | :[B] '''French Flag''' - Steven and Zoltan | ||
:[C] '''Putting BS into us?/BS against disease or diseased water?''' - Richard | :[C] '''Putting BS into us?/BS against disease or diseased water?''' - Richard | ||
- | |||
Sub-project | Sub-project | ||
:[D] '''MAZef kill switch''' | :[D] '''MAZef kill switch''' | ||
- | |||
====DECISION of PROJECT:==== | ====DECISION of PROJECT:==== | ||
Line 36: | Line 32: | ||
*Likely situation: Choose top 3 projects – Present on Wed 3rd - formal meeting | *Likely situation: Choose top 3 projects – Present on Wed 3rd - formal meeting | ||
*If can’t decide on which project – put it to the vote (like last year!) | *If can’t decide on which project – put it to the vote (like last year!) | ||
- | |||
====PRESENTATIONS:==== | ====PRESENTATIONS:==== | ||
Line 47: | Line 42: | ||
*Use Google Scholar | *Use Google Scholar | ||
*Major Weakness of many previous iGEM teams – Modelling is tagged onto Lab work. We should perform modelling-informed lab work | *Major Weakness of many previous iGEM teams – Modelling is tagged onto Lab work. We should perform modelling-informed lab work | ||
- | |||
- | |||
- | |||
====TIMELINE:==== | ====TIMELINE:==== | ||
Line 61: | Line 53: | ||
*Team Roster – Finalise who is coming to the Jamboree – twice? | *Team Roster – Finalise who is coming to the Jamboree – twice? | ||
- | |||
- | |||
==== Action Points:==== | ==== Action Points:==== | ||
Line 73: | Line 63: | ||
#Complete Data mining | #Complete Data mining | ||
# Purchase/try Natto!!!!! | # Purchase/try Natto!!!!! | ||
- | |||
====Other businesses:==== | ====Other businesses:==== | ||
*Harsh’s cheaper/quicker flight to Boston option - Booking has to go through University still. Would be helpful to identify flights | *Harsh’s cheaper/quicker flight to Boston option - Booking has to go through University still. Would be helpful to identify flights | ||
- | |||
====Ideas==== | ====Ideas==== |
Revision as of 22:52, 25 October 2010
![]() | |||||||||||||
|
Contents |
Formal Meeting - 24 February 2010
- Start time: 3.10-5.35 pm
- Room 922
- Attendance
- Present: Da (Computer), Harsh, Jannetta, Rachel (Chair), Younus (Minutes), Zoltan, Richard, Steven, Anil, Jen, Matt
- Apologies: Alan, Phil
Updates
- iGEM 2010 Team Newcastle Registered
- Final Date for Jamboree 5-8th Nov?
SHORTLIST SO FAR:
Project ideas – team members assigned to look into this projects TOP FIVE
- [1] Computing DNA - Rachel, Zoltan, Steven
- [2] Microcracks in Concrete - Harsh, Da, Alan
- [3] BactoNatto, Teeth, Coating spores/BS - Rachel, Younus, Jannetta
- [4] Headlice - Richard, Janetta,Phil
- [5] Linearising DNA - Richard, Phil, Zoltan
Possible other projects
- [A] Diabetes - Da, Younus and Harsh
- [B] French Flag - Steven and Zoltan
- [C] Putting BS into us?/BS against disease or diseased water? - Richard
Sub-project
- [D] MAZef kill switch
DECISION of PROJECT:
- Ideal situation: All decide on one project on Friday – Present idea on Wed
- Likely situation: Choose top 3 projects – Present on Wed 3rd - formal meeting
- If can’t decide on which project – put it to the vote (like last year!)
PRESENTATIONS:
- About 5 minutes, 3-4 slides.
- Work in assigned groups of three
- demonstrate project is viable/explain how it works + problems/issues
- Start looking at a lower level i.e. which genes involved
- Start looking at modelling languages, SPML, environments?
- Use Google Scholar
- Major Weakness of many previous iGEM teams – Modelling is tagged onto Lab work. We should perform modelling-informed lab work
TIMELINE:
For the Summary table for AW & JH:
- Different Individuals holidays should by included
- For personal and practical issues
- To get a picture of when everyone is available
- List of all tasks with hard deadlines highlighted
- T-Shirts/Poster – not a single point
- Misc?
- Team Roster – Finalise who is coming to the Jamboree – twice?
Action Points:
- All members to apply for membership for iGEM 2010 Team Newcastle
- AW & JW to e-mail Jannetta and Phil about Timeline summary
- Visas/Passports – Check whether visas required/If passports in date.
- Zoltan and Harsh –
- British Passport -> don’t need visa but need to fill in online form
- JH, AW and M… already have visas from last years
- Complete Data mining
- Purchase/try Natto!!!!!
Other businesses:
- Harsh’s cheaper/quicker flight to Boston option - Booking has to go through University still. Would be helpful to identify flights
Ideas
[1] Computing DNA
- Kill switch
- Modifying bacteria so that as they evolve they move closer or further away from answering a problem
- Bacteria survive if close to answer [1?], die if further away from answer [0?]
- Hamiltonian Pathway
[2] Microcracks in Concrete
- Spray bacteria into concrete
- spray nutrients, when nutrients run out – forms a polymer/biofilm
- fills cracks by producing e.g. polymer, protein, CaCO3 etc.
- Difficulty – way of detecting cracks - X-rays
- Great wall of China – used rice – still there!
- Worlds strongest Glue – Camylobacter cresentus
- Spider silk – contracts as it dries – could be like reinforced concrete
- Spores germinate when cracks get bigger – start to grow again!
- Applications: Cracks in space shuttles, shoes
- Advantage over normal glue? BS can get to cracks, where normal glue cannot!
- Well-known problem – microcracks will develop into bigger cracks
- Chemical engineer would be required
[3]BactoNatto, Teeth, Coating spores/BS
- S. mutans binding to ... in teeth -> decay teeth
- displace this organism with BS
- 90 day protection?
- Spoon of this - mix into anything?
- MIT 2007 -> didnt manage to transform lactobacillus with specific plasmid
- Would have to use a computer stimulation of teeth
- Chocolate/vanilla/banana flavoured Natto!
- Miracal cure
- with Fluorides, Omega, Vitamins [D], Minerals etc.
[4] Headlice
- Male stomach discs?
- Female symbiotic relationship with bacteria
- How to introduce BS?
- Lice v hard to get rid of
- Bacillus Stringensis?
[5] Linearising DNA
- bacteria with linear chromosomes/plasmids - Agrobacteria?
- Streptomyces ... also has linear DNA
- problem of replication - as it is normally bidirectional
- Richard's two papers
- Flipase/RecA?
[B] French Flag
- spatial and temporal organisation-self organisation
- bacteria grow in a certain pattern without external stimuli - they decide on the basis of local stimuli
- Game of life and Rock, Paper Sissors game by Southampton 2009
- See also Osaka2009