Latest revision as of 20:37, 25 October 2010

Mutant Data Table

Mutant Name	Features and Mutations	Transpeptidation per DCP	Hydrolysis per DCP
CapD	No Signal Sequence, Triple band on protein agarose gel	0.491	0.713
CapD_CP	Foldit created linker, Circular Permutation, No Signal Sequence, Single band on protein agarose gel	1.000	1.000
CapD_CPNFDelta	Foldit created linker, Circular Permutation, No Signal Sequence, Single band on protein agarose gel, Removed "floppy" section to compact protein	1.035	0.878
F24A	Point mutation at residue 24 on CapDCP from Phenylalanine to Alanine, Foldit-created linker, Circular Permutation, No Signal Sequence, Single band on protein agarose gel	0.021	0.061
F24H	Point mutation at residue 24 on CapDCP from Phenylalanine to Histidine, Foldit-created linker, Circular Permutation, No Signal Sequence, Single band on protein agarose gel	0.108	1.205
F24H, L40R, T59D_M61S	Point mutation at residues 24, 40, 59, and 61 on Foldit design from Phenylalanine to Histidine, Leucine to Arginine, Threonine to Asparagine, and Methionine to Serine, respectively. Foldit-created linker, Circular Permutation, No Signal Sequence, Single band on protein agarose gel	0.001	0.006
F24H, L40R, T59N_M61S	Point mutation at residues 24, 40, 59, and 61 on Foldit design from Phenylalanine to Histidine, Leucine to Arginine, Threonine to Aspartic Acid, and Methionine to Serine, respectively. Foldit-created linker, Circular Permutation, No Signal Sequence, Single band on protein agarose gel	0.058	1.050
F24H, L40R, T59S_M61S	Point mutation at residues 24, 40, 59, and 61 on CapDCP from Phenylalanine to Histidine, Leucine to Arginine, Threonine to Serine, and Methionine to Serine, respectively. Foldit-created linker, Circular Permutation, No Signal Sequence, Single band on protein agarose gel	0.000	0.007
F24H, R356K	Point mutation at residues 24 and 356 on CapDCP from Phenylalanine to Histidine and Arginine to Lysine, respectively. Foldit-created linker, Circular Permutation, No Signal Sequence, Single band on protein agarose gel	0.129	0.257
F24H, T59R	Point mutation at residues 24 and 59 on CapDCPfrom Phenylalanine to Histidine and Threonine to Arginine, respectively. Foldit-created linker, Circular Permutation, No Signal Sequence, Single band on protein agarose gel	0.011	0.005
F24H,T59N	Point mutation at residues 24 and 59 on CapDCP from Phenylalanine to Histidine and Threonine to Asparagine, respectively. Foldit-created linker, Circular Permutation, No Signal Sequence, Single band on protein agarose gel	0.007	0.029
F24W	Point mutation at residue 24 on CapDCP from Phenylalanine to Tryptophan. Foldit-created linker, Circular Permutation, No Signal Sequence, Single band on protein agarose gel	0.006	0.044
F24Y	Point mutation at residue 24 on CapDCP from Phenylalanine to Tyrosine. Foldit-created linker, Circular Permutation, No Signal Sequence, Single band on protein agarose gel	0.593	0.887
F24Y, L40R	Point mutation at residues 24 and 40 on CapDCP from Phenylalanine to Tyrosine and Leucine to Arginine, respectively. Foldit-created linker, Circular Permutation, No Signal Sequence, Single band on protein agarose gel	0.009	-0.013
F24Y, L40R, T59N	Point mutation at residues 24, 40, 59 on CapDCP from Phenylalanine to Tyrosine, Leucine to Arginine, and Threonine to Asparagine, respectively. Foldit-created linker, Circular Permutation, No Signal Sequence, Single band on protein agarose gel	0.003	0.157
F24Y,R305K	Point mutation at residues 24 and 305 on CapDCP from Phenylalanine to Tyrosine and Arginine to Lysine, respectively. Foldit-created linker, Circular Permutation, No Signal Sequence, Single band on protein agarose gel	0.002	0.233
F24Y,T59N	Point mutation at residues 24 and 59 on CapDCP from Phenylalanine to Tyrosine and Threonine to Asparagine, respectively. Foldit-created linker, Circular Permutation, No Signal Sequence, Single band on protein agarose gel	0.008	0.165
F24Y,T59N,R305K	Point mutation at residues 24, 59, and 356 on CapDCP from Phenylalanine to Tyrosine, Threonine to Asparagine, and Arginine to Lysine, respectively. Foldit-created linker, Circular Permutation, No Signal Sequence, Single band on protein agarose gel	0.002	0.127
F60W	Point mutation at residue 60 on CapDCP from Phenylalanine to Tryptophan. Foldit-created linker, Circular Permutation, No Signal Sequence, Single band on protein agarose gel	0.239	0.489
G79A	Point mutation at residue 79 on CapDCP from Glycine to Alanine. Foldit-created linker, Circular Permutation, No Signal Sequence, Single band on protein agarose gel	0.040	-0.511
I83T	Point mutation at residue 83 on CapDCP from Isoleucine to Threonine. Foldit-created linker, Circular Permutation, No Signal Sequence, Single band on protein agarose gel	0.009	0.006
I83V	Point mutation at residue 83 on CapDCP from Isoleucine to Valine. Foldit-created linker, Circular Permutation, No Signal Sequence, Single band on protein agarose gel	0.003	0.043
L40A	Point mutation at residue 40 on CapDCP from Leucine to Alanine. Foldit-created linker, Circular Permutation, No Signal Sequence, Single band on protein agarose gel	0.150	0.413
L40R	Point mutation at residue 40 on CapDCP from Leucine to Arginine. Foldit-created linker, Circular Permutation, No Signal Sequence, Single band on protein agarose gel	1.157	1.527
L40S	Point mutation at residue 40 on CapDCP from Leucine to Serine. Foldit-created linker, Circular Permutation, No Signal Sequence, Single band on protein agarose gel	0.166	0.577
L40W	Point mutation at residue 40 on CapDCP from Leucine to Tryptophan. Foldit-created linker, Circular Permutation, No Signal Sequence, Single band on protein agarose gel	0.825	1.215
M61H	Point mutation at residue 61 on CapDCP from Methionine to Histidine. Foldit-created linker, Circular Permutation, No Signal Sequence, Single band on protein agarose gel	-0.003	0.002
M61N	Point mutation at residue 61 on CapDCP from Methionine to Asparagine. Foldit-created linker, Circular Permutation, No Signal Sequence, Single band on protein agarose gel	0.011	0.002
M61S	Point mutation at residue 61 on CapDCP from Methionine to Serine. Foldit-created linker, Circular Permutation, No Signal Sequence, Single band on protein agarose gel	0.262	0.485
N23K	Point mutation at residue 23 on CapDCP from Asparagine to Lysine. Foldit-created linker, Circular Permutation, No Signal Sequence, Single band on protein agarose gel	0.818	0.839
N23Q	Point mutation at residue 23 on CapDCP from Asparagine to Glutamine. Foldit-created linker, Circular Permutation, No Signal Sequence, Single band on protein agarose gel	0.165	0.646
S143K	Point mutation at residue 143 on CapDCP from Serine to Lysine. Foldit-created linker, Circular Permutation, No Signal Sequence, Single band on protein agarose gel	0.574	0.426
S22I, T59A	Point mutation at residues 22 and 59 on CapDCP from Serine to Isoleucine and Threonine to Alanine, respectively. Foldit-created linker, Circular Permutation, No Signal Sequence, Single band on protein agarose gel	0.030	-0.057
S22Q, T59Q	Point mutation at residues 22 and 59 on CapDCP from Serine to Glutamine and Threonine to Glutamine, respectively. Foldit-created linker, Circular Permutation, No Signal Sequence, Single band on protein agarose gel	-0.012	0.085
S57H, M61H	Point mutation at residues 57 and 61 on CapDCP from Serine to Histidine and Methionine to Histidine, respectively. Foldit-created linker, Circular Permutation, No Signal Sequence, Single band on protein agarose gel	-0.004	-0.007
T18L, T59Q, M61N, F452W	Point mutation at residues 18, 59, 61, and 452 on CapDCP from Threonine to Leucine, Threonine to Glutamine, Methionine to Asparagine, and Phenylalanine to Tryptophan, respectively. Foldit-created linker, Circular Permutation, No Signal Sequence, Single band on protein agarose gel	0.020	-0.028
T18S_T20S	Point mutation at residues 18 and 20 on CapDCP from Threonine to Serine and Threonine to Serine, respectively. Foldit-created linker, Circular Permutation, No Signal Sequence, Single band on protein agarose gel	0.617	1.186
T20A	Point mutation at residue 20 on CapDCP from Threonine to Alanine. Foldit-created linker, Circular Permutation, No Signal Sequence, Single band on protein agarose gel	0.011	0.021
T20C	Point mutation at residue 20 on CapDCP from Threonine to Cystine. Foldit-created linker, Circular Permutation, No Signal Sequence, Single band on protein agarose gel	0.090	0.142
T20S	Point mutation at residue 20 on CapDCP from Threonine to Serine. Foldit-created linker, Circular Permutation, No Signal Sequence, Single band on protein agarose gel	0.639	1.443
T20S, L40D	Point mutation at residues 20 and 40 on CapDCP from Threonine to Serine and Leucine to Asparagine, respectively. Foldit-created linker, Circular Permutation, No Signal Sequence, Single band on protein agarose gel	0.853	0.001
T20S, L40E	Point mutation at residues 20 and 40 on CapDCP from Threonine to Serine and Leucine to Glutamic Acid, respectively. Foldit-created linker, Circular Permutation, No Signal Sequence, Single band on protein agarose gel	0.163	0.637
T20S, L40F	Point mutation at residues 20 and 40 on CapDCP from Threonine to Serine and Leucine to Phenylalanine, respectively. Foldit-created linker, Circular Permutation, No Signal Sequence, Single band on protein agarose gel	0.246	0.335
T20S, L40H	Point mutation at residues 20 and 40 on CapDCP from Threonine to Serine and Leucine to Histidine, respectively. Foldit-created linker, Circular Permutation, No Signal Sequence, Single band on protein agarose gel	0.001	0.012
T20S, L40K	Point mutation at residues 20 and 40 on CapDCP from Threonine to Serine and Leucine to Lysine, respectively. Foldit-created linker, Circular Permutation, No Signal Sequence, Single band on protein agarose gel	0.000	0.007
T20S, L40Q	Point mutation at residues 20 and 40 on CapDCP from Threonine to Serine and Leucine to Glutamine, respectively. Foldit-created linker, Circular Permutation, No Signal Sequence, Single band on protein agarose gel	0.126	0.478
T20S, L40R	Point mutation at residues 20 and 40 on CapDCP from Threonine to Serine and Leucine to Arginine, respectively. Foldit-created linker, Circular Permutation, No Signal Sequence, Single band on protein agarose gel	0.000	0.009
T20S, L40R, F60E	Point mutation at residues 20, 40, and 60 on CapDCP from Threonine to Serine, Leucine to Arginine, and Phenylalanine to Glutamic Acid, respectively. Foldit-created linker, Circular Permutation, No Signal Sequence, Single band on protein agarose gel	0.048	0.028
T20S, L40R, F60Q	Point mutation at residues 20, 40, and 60 on CapDCP from Threonine to Serine, Leucine to Arginine, and Phenylalanine to Glutamine, respectively. Foldit-created linker, Circular Permutation, No Signal Sequence, Single band on protein agarose gel	0.002	0.007
T20S, L40R, N81E	Point mutation at residues 20, 40, and 60 on CapDCP from Threonine to Serine, Leucine to Arginine, and Phenylalanine to Glutamine, respectively. Foldit-created linker, Circular Permutation, No Signal Sequence, Single band on protein agarose gel	0.001	-0.004
T20S, L40R, N81Q	Point mutation at residues 20, 40, and 81 on CapDCP from Threonine to Serine, Leucine to Arginine, and Asparagine to Glutamine, respectively. Foldit-created linker, Circular Permutation, No Signal Sequence, Single band on protein agarose gel	0.422	0.321
T20S, L40R, T59K	Point mutation at residues 20, 40, and 59 on CapDCP from Threonine to Serine, Leucine to Arginine, and Threonine to Lysine, respectively. Foldit-created linker, Circular Permutation, No Signal Sequence, Single band on protein agarose gel	0.048	0.033
T20S, L40R, T59K_M61S	Point mutation at residues 20, 40, 59, and 61 on CapDCP from Threonine to Serine, Leucine to Arginine, Threonine to Lysine, and Methionine to Serine, respectively. Foldit-created linker, Circular Permutation, No Signal Sequence, Single band on protein agarose gel	0.010	0.032
T20S, T59Q, M61T	Point mutation at residues 20, 59, and 61 on CapDCP from Threonine to Serine, Threonine to Glutamine, and Methionine to Threonine, respectively. Foldit-created linker, Circular Permutation, No Signal Sequence, Single band on protein agarose gel	0.007	-0.069
T20S,M61A	Point mutation at residues 20 and 61 on CapDCP from Threonine to Serine and Methionine to Alanine, respectively. Foldit-created linker, Circular Permutation, No Signal Sequence, Single band on protein agarose gel	0.005	0.045
T20S,M61C	Point mutation at residues 20 and 61 on CapDCP from Threonine to Serine and Methionine to Cystine, respectively. Foldit-created linker, Circular Permutation, No Signal Sequence, Single band on protein agarose gel	0.102	0.207
T20S,M61D	Point mutation at residues 20 and 61 on CapDCP from Threonine to Serine and Methionine to Aspartic Acid, respectively. Foldit-created linker, Circular Permutation, No Signal Sequence, Single band on protein agarose gel	0.004	0.003
T20S,M61G	Point mutation at residues 20 and 61 on CapDCP from Threonine to Serine and Methionine to Glycine, respectively. Foldit-created linker, Circular Permutation, No Signal Sequence, Single band on protein agarose gel	0.004	0.029
T20S,M61L	Point mutation at residues 20 and 61 on CapDCP from Threonine to Serine and Methionine to Leucine, respectively. Foldit-created linker, Circular Permutation, No Signal Sequence, Single band on protein agarose gel	0.004	0.029
T20S,M61N	Point mutation at residues 20 and 61 on CapDCP from Threonine to Serine and Methionine to Asparagine, respectively. Foldit-created linker, Circular Permutation, No Signal Sequence, Single band on protein agarose gel	0.003	0.002
T20S,M61S	Point mutation at residues 20 and 61 on CapDCP from Threonine to Serine and Methionine to Serine, respectively. Foldit-created linker, Circular Permutation, No Signal Sequence, Single band on protein agarose gel	0.007	0.053
T20S,M61T	Point mutation at residues 20 and 61 on CapDCP from Threonine to Serine and Methionine to Threonine, respectively. Foldit-created linker, Circular Permutation, No Signal Sequence, Single band on protein agarose gel	0.038	0.363
T20S,M61V	Point mutation at residues 20 and 61 on CapDCP from Threonine to Serine and Methionine to Valine, respectively. Foldit-created linker, Circular Permutation, No Signal Sequence, Single band on protein agarose gel	0.004	0.039
T20S,T59N	Point mutation at residues 20 and 59 on CapDCP from Threonine to Serine and Threonine to Asparagine, respectively. Foldit-created linker, Circular Permutation, No Signal Sequence, Single band on protein agarose gel	0.019	0.125
T20S,T59S_M61S	Point mutation at residues 20, 59, and 61 on CapDCP from Threonine to Serine, Threonine to Serine, and Methionine to Serine, respectively. Foldit-created linker, Circular Permutation, No Signal Sequence, Single band on protein agarose gel	0.300	0.719
T20S_F24H	Point mutation at residues 20 and 24 on CapDCP from Threonine to Serine and Phenylalanine to Histidine, respectively. Foldit-created linker, Circular Permutation, No Signal Sequence, Single band on protein agarose gel	0.008	0.097
T20S_F24Y	Point mutation at residues 20 and 24 on CapDCP from Threonine to Serine and Phenylalanine to Tyrosine, respectively. Foldit-created linker, Circular Permutation, No Signal Sequence, Single band on protein agarose gel	0.040	0.201
T20S_F24Y,T59N	Point mutation at residues 20, 24, and 59 on CapDCP from Threonine to Serine, Phenylalanine to Tyrosine, and Threonine to Asparagine, respectively. Foldit-created linker, Circular Permutation, No Signal Sequence, Single band on protein agarose gel	0.013	0.048
T2A	Point mutation at residue 2 on CapDCP from Threonine to Alanine. Foldit-created linker, Circular Permutation, No Signal Sequence, Single band on protein agarose gel	0.007	-0.020
T2C	Point mutation at residue 2 on CapDCP from Threonine to Cystine. Foldit-created linker, Circular Permutation, No Signal Sequence, Single band on protein agarose gel	0.001	-0.005
T2S	Point mutation at residue 2 on CapDCP from Threonine to Serine. Foldit-created linker, Circular Permutation, No Signal Sequence, Single band on protein agarose gel	0.024	0.325
T2S,T18S_T20S	Point mutation at residues 2, 18, and 20 on CapDCP from Threonine to Serine, Threonine to Serine, and Threonine to Serine, respectively. Foldit-created linker, Circular Permutation, No Signal Sequence, Single band on protein agarose gel	0.144	0.250
T2S,T18S_T20S,T59S_M61S	Point mutation at residues 2, 18, 20, 59, and 61 on CapDCP from Threonine to Serine, Threonine to Serine, Threonine to Serine, Threonine to Serine and Threonine to Serine, respectively. Foldit-created linker, Circular Permutation, No Signal Sequence, Single band on protein agarose gel	0.003	0.022
T2S,T20S	Point mutation at residues 2 and 20 on CapDCP from Threonine to Serine and Threonine to Serine, respectively. Foldit-created linker, Circular Permutation, No Signal Sequence, Single band on protein agarose gel	0.106	0.089
T2V	Point mutation at residue 2 on CapDCP from Threonine to Valine. Foldit-created linker, Circular Permutation, No Signal Sequence, Single band on protein agarose gel	0.000	0.000
T59H_M61A	Point mutation at residues 59 and 61 on CapDCP from Threonine to Histidine and Methionine to Alanine, respectively. Foldit-created linker, Circular Permutation, No Signal Sequence, Single band on protein agarose gel	0.000	0.000
T59H_M61T	Point mutation at residues 59 and 61 on CapDCP from Threonine to Histidine and Methionine to Threonine, respectively. Foldit-created linker, Circular Permutation, No Signal Sequence, Single band on protein agarose gel	0.000	0.000
T59M	Point mutation at residue 59 on CapDCP from Threonine to Methionine. Foldit-created linker, Circular Permutation, No Signal Sequence, Single band on protein agarose gel	0.008	0.008
T59N	Point mutation at residue 59 on CapDCP from Threonine to Asparagine. Foldit-created linker, Circular Permutation, No Signal Sequence, Single band on protein agarose gel	0.232	0.868
T59Q	Point mutation at residue 59 on CapDCP from Threonine to Glutamine. Foldit-created linker, Circular Permutation, No Signal Sequence, Single band on protein agarose gel	0.000	0.000
T59Q, M61Q, F452W	Point mutation at residues 59, 61, and 452 on CapDCP from Threonine to Glutamine, Threonine to Glutamine, and Phenylalanine to Tryptophan, respectively. Foldit-created linker, Circular Permutation, No Signal Sequence, Single band on protein agarose gel	-0.014	0.037
T59S	Point mutation at residue 59 on CapDCP from Threonine to Serine. Foldit-created linker, Circular Permutation, No Signal Sequence, Single band on protein agarose gel	3.525	1.047
T59S, M61H	Point mutation at residues 59 and 61 on CapDCP from Threonine to Serine and Methionine to Histidine, respectively. Foldit-created linker, Circular Permutation, No Signal Sequence, Single band on protein agarose gel	0.013	0.051

← Back to Testing the Gram(+) Therapeutic

@@ Line 1: / Line 1: @@
+__NOTOC__
+{{Template:Team:Washington/Templates/Header}}
+<html>
+<script type="text/javascript">
+$(function() {
+  var mainimg = document.getElementById("mainimg");
+  var default_src = mainimg.src;
+  var restore_mainimg = function() {
+    mainimg.src = default_src;
+  };
+  $(document.getElementById("area_target")).hover(function() {
+    mainimg.src = "/wiki/images/1/1d/Main_graphic2_target.png";
+  }, restore_mainimg);
+  $(document.getElementById("area_secretion")).hover(function() {
+    mainimg.src = "/wiki/images/2/23/Main_graphic2_secretion.png";
+  }, restore_mainimg);
+  $(document.getElementById("area_display")).hover(function() {
+    mainimg.src = "/wiki/images/a/aa/Main_graphic2_display.png";
+  }, restore_mainimg);
+  $(document.getElementById("area_release")).hover(function() {
+    mainimg.src = "/wiki/images/e/ed/Main_graphic2_release.png";
+  }, restore_mainimg);
+});
+</script>
+</html>
+<!---------------------------------------PAGE CONTENT GOES BELOW THIS---------------------------------------->
 <html xmlns:v="urn:schemas-microsoft-com:vml"
 xmlns:o="urn:schemas-microsoft-com:office:office"
@@ Line 5: / Line 33: @@
 <head>
-<meta name="Excel Workbook Frameset">
 <meta http-equiv=Content-Type content="text/html; charset=windows-1252">
 <meta name=ProgId content=Excel.Sheet>
 <meta name=Generator content="Microsoft Excel 14">
 <link rel=File-List href="MutantData%20Table_files/filelist.xml">
-<title>Mutant&nbsp;Data&nbsp;Table</title>
+<!--[if !mso]>
-<![if !supportTabStrip]>
+<style>
-<link id="shLink" href="MutantData%20Table_files/sheet001.htm">
+v\:* {behavior:url(#default#VML);}
+o\:* {behavior:url(#default#VML);}
+x\:* {behavior:url(#default#VML);}
+.shape {behavior:url(#default#VML);}
+</style>
+<![endif]-->
+<style id="MutantData Table_13667_Styles">
+<!--table
+	{mso-displayed-decimal-separator:"\.";
+	mso-displayed-thousand-separator:"\,";}
+.font513667
+	{color:black;
+	font-size:9.0pt;
+	font-weight:400;
+	font-style:normal;
+	text-decoration:none;
+	font-family:Tahoma, sans-serif;
+	mso-font-charset:0;}
+.xl6413667
+	{padding:0px;
+	mso-ignore:padding;
+	color:black;
+	font-size:11.0pt;
+	font-weight:400;
+	font-style:normal;
+	text-decoration:none;
+	font-family:Calibri, sans-serif;
+	mso-font-charset:0;
+	mso-number-format:General;
+	text-align:center;
+	vertical-align:middle;
+	mso-background-source:auto;
+	mso-pattern:auto;
+	white-space:normal;
+	mso-text-control:shrinktofit;}
+.xl6513667
+	{padding:0px;
+	mso-ignore:padding;
+	color:black;
+	font-size:11.0pt;
+	font-weight:400;
+	font-style:normal;
+	text-decoration:none;
+	font-family:Calibri, sans-serif;
+	mso-font-charset:0;
+	mso-number-format:General;
+	text-align:left;
+	vertical-align:top;
+	mso-background-source:auto;
+	mso-pattern:auto;
+	white-space:normal;
+	mso-text-control:shrinktofit;}
+.xl6613667
+	{padding:0px;
+	mso-ignore:padding;
+	color:black;
+	font-size:11.0pt;
+	font-weight:400;
+	font-style:normal;
+	text-decoration:none;
+	font-family:Calibri, sans-serif;
+	mso-font-charset:0;
+	mso-number-format:General;
+	text-align:left;
+	vertical-align:top;
+	mso-background-source:auto;
+	mso-pattern:auto;
+	white-space:normal;}
+.xl6713667
+	{padding:0px;
+	mso-ignore:padding;
+	color:windowtext;
+	font-size:10.0pt;
+	font-weight:400;
+	font-style:normal;
+	text-decoration:none;
+	font-family:Verdana, sans-serif;
+	mso-font-charset:0;
+	mso-number-format:General;
+	text-align:left;
+	vertical-align:top;
+	mso-background-source:auto;
+	mso-pattern:auto;
+	white-space:normal;}
+.xl6813667
+	{padding:0px;
+	mso-ignore:padding;
+	color:windowtext;
+	font-size:10.0pt;
+	font-weight:400;
+	font-style:normal;
+	text-decoration:none;
+	font-family:Verdana, sans-serif;
+	mso-font-charset:0;
+	mso-number-format:"0\.000";
+	text-align:left;
+	vertical-align:top;
+	mso-background-source:auto;
+	mso-pattern:auto;
+	white-space:normal;}
+.xl6913667
+	{padding:0px;
+	mso-ignore:padding;
+	color:black;
+	font-size:11.0pt;
+	font-weight:400;
+	font-style:normal;
+	text-decoration:none;
+	font-family:Calibri, sans-serif;
+	mso-font-charset:0;
+	mso-number-format:"0\.000";
+	text-align:left;
+	vertical-align:top;
+	mso-background-source:auto;
+	mso-pattern:auto;
+	white-space:normal;}
+.xl7013667
+	{padding:0px;
+	mso-ignore:padding;
+	color:black;
+	font-size:11.0pt;
+	font-weight:400;
+	font-style:normal;
+	text-decoration:none;
+	font-family:Calibri, sans-serif;
+	mso-font-charset:0;
+	mso-number-format:General;
+	text-align:left;
+	vertical-align:top;
+	background:white;
+	mso-pattern:black none;
+	white-space:normal;
+	mso-text-control:shrinktofit;}
+-->
+</style>
+<title>Mutant Data Table</title>
+</head>
-<link id="shLink">
+<body>
+<!--[if !excel]>&nbsp;&nbsp;<![endif]-->
+<!--The following information was generated by Microsoft Excel's Publish as Web
+Page wizard.-->
+<!--If the same item is republished from Excel, all information between the DIV
+tags will be replaced.-->
+<!----------------------------->
+<!--START OF OUTPUT FROM EXCEL PUBLISH AS WEB PAGE WIZARD -->
+<!----------------------------->
-<script language="JavaScript">
+<div id="MutantData Table_13667" align=center x:publishsource="Excel">
-<!--
- var c_lTabs=1;
- var c_rgszSh=new Array(c_lTabs);
+<h1 style='color:black;font-family:Calibri;font-size:14.0pt;font-weight:800;
- c_rgszSh[0] = "MutantData Table";
+font-style:normal'>Mutant Data Table</h1>
+<table border=0 cellpadding=0 cellspacing=0 width=805 class=xl6413667
+ style='border-collapse:collapse;table-layout:fixed;width:604pt'>
+ <col class=xl6413667 width=172 style='mso-width-source:userset;mso-width-alt:
+;width:129pt'>
+ <col class=xl6413667 width=297 style='mso-width-source:userset;mso-width-alt:
+;width:223pt'>
+ <col class=xl6413667 width=168 span=2 style='mso-width-source:userset;
+ mso-width-alt:6144;width:126pt'>
+ <tr height=26 style='mso-height-source:userset;height:20.1pt'>
+  <td height=26 class=xl7013667 width=172 style='height:20.1pt;width:129pt'>Mutant
+  Name</td>
+  <td class=xl7013667 width=297 style='width:223pt'>Features and Mutations</td>
+  <td class=xl6613667 width=168 style='width:126pt'>Transpeptidation per DCP</td>
+  <td class=xl6613667 width=168 style='width:126pt'>Hydrolysis per DCP</td>
+ </tr>
+ <tr height=93 style='mso-height-source:userset;height:69.95pt'>
+  <td height=93 class=xl6713667 width=172 style='height:69.95pt;width:129pt'>CapD</td>
+  <td class=xl6513667 width=297 style='width:223pt'>No Signal Sequence, Triple
+  band on protein agarose gel</td>
+  <td class=xl6813667 width=168 style='width:126pt'>0.491</td>
+  <td class=xl6813667 width=168 style='width:126pt'>0.713</td>
+ </tr>
+ <tr height=93 style='mso-height-source:userset;height:69.95pt'>
+  <td height=93 class=xl6613667 width=172 style='height:69.95pt;width:129pt'>CapD_CP</td>
+  <td class=xl6513667 width=297 style='width:223pt'>Foldit created linker,
+  Circular Permutation, No Signal Sequence, Single band on protein agarose gel</td>
+  <td class=xl6913667 width=168 style='width:126pt'>1.000</td>
+  <td class=xl6913667 width=168 style='width:126pt'>1.000</td>
+ </tr>
+ <tr height=93 style='mso-height-source:userset;height:69.95pt'>
+  <td height=93 class=xl6613667 width=172 style='height:69.95pt;width:129pt'>CapD_CPNFDelta</td>
+  <td class=xl6513667 width=297 style='width:223pt'>Foldit created linker,
+  Circular Permutation, No Signal Sequence, Single band on protein agarose gel,
+  Removed &quot;floppy&quot; section to compact protein</td>
+  <td class=xl6913667 width=168 style='width:126pt'>1.035</td>
+  <td class=xl6913667 width=168 style='width:126pt'>0.878</td>
+ </tr>
+ <tr height=93 style='mso-height-source:userset;height:69.95pt'>
+  <td height=93 class=xl6613667 width=172 style='height:69.95pt;width:129pt'>F24A</td>
+  <td class=xl6513667 width=297 style='width:223pt'>Point mutation at residue
+on CapDCP from Phenylalanine to Alanine, Foldit-created linker, Circular
+  Permutation, No Signal Sequence, Single band on protein agarose gel</td>
+  <td class=xl6913667 width=168 style='width:126pt'>0.021</td>
+  <td class=xl6913667 width=168 style='width:126pt'>0.061</td>
+ </tr>
+ <tr height=93 style='mso-height-source:userset;height:69.95pt'>
+  <td height=93 class=xl6713667 width=172 style='height:69.95pt;width:129pt'>F24H</td>
+  <td class=xl6513667 width=297 style='width:223pt'>Point mutation at residue
+on CapDCP from Phenylalanine to Histidine, Foldit-created linker, Circular
+  Permutation, No Signal Sequence, Single band on protein agarose gel</td>
+  <td class=xl6813667 width=168 style='width:126pt'>0.108</td>
+  <td class=xl6813667 width=168 style='width:126pt'>1.205</td>
+ </tr>
+ <tr height=93 style='mso-height-source:userset;height:69.95pt'>
+  <td height=93 class=xl6713667 width=172 style='height:69.95pt;width:129pt'>F24H,
+  L40R, T59D_M61S</td>
+  <td class=xl6513667 width=297 style='width:223pt'>Point mutation at residues
+, 40, 59, and 61 on Foldit design from Phenylalanine to Histidine, Leucine
+  to Arginine, Threonine to Asparagine, and Methionine to Serine, respectively.
+  Foldit-created linker, Circular Permutation, No Signal Sequence, Single band
+  on protein agarose gel</td>
+  <td class=xl6813667 width=168 style='width:126pt'>0.001</td>
+  <td class=xl6813667 width=168 style='width:126pt'>0.006</td>
+ </tr>
+ <tr height=93 style='mso-height-source:userset;height:69.95pt'>
+  <td height=93 class=xl6713667 width=172 style='height:69.95pt;width:129pt'>F24H,
+  L40R, T59N_M61S</td>
+  <td class=xl6513667 width=297 style='width:223pt'>Point mutation at residues
+, 40, 59, and 61 on Foldit design from Phenylalanine to Histidine, Leucine
+  to Arginine, Threonine to Aspartic Acid, and Methionine to Serine,
+  respectively. Foldit-created linker, Circular Permutation, No Signal
+  Sequence, Single band on protein agarose gel</td>
+  <td class=xl6813667 width=168 style='width:126pt'>0.058</td>
+  <td class=xl6813667 width=168 style='width:126pt'>1.050</td>
+ </tr>
+ <tr height=93 style='mso-height-source:userset;height:69.95pt'>
+  <td height=93 class=xl6713667 width=172 style='height:69.95pt;width:129pt'>F24H,
+  L40R, T59S_M61S</td>
+  <td class=xl6513667 width=297 style='width:223pt'>Point mutation at residues
+, 40, 59, and 61 on CapDCP from Phenylalanine to Histidine, Leucine to
+  Arginine, Threonine to Serine, and Methionine to Serine, respectively.
+  Foldit-created linker, Circular Permutation, No Signal Sequence, Single band
+  on protein agarose gel</td>
+  <td class=xl6813667 width=168 style='width:126pt'>0.000</td>
+  <td class=xl6813667 width=168 style='width:126pt'>0.007</td>
+ </tr>
+ <tr height=93 style='mso-height-source:userset;height:69.95pt'>
+  <td height=93 class=xl6613667 width=172 style='height:69.95pt;width:129pt'>F24H,
+  R356K</td>
+  <td class=xl6513667 width=297 style='width:223pt'>Point mutation at residues
+and 356 on CapDCP from Phenylalanine to Histidine and Arginine to Lysine,
+  respectively. Foldit-created linker, Circular Permutation, No Signal
+  Sequence, Single band on protein agarose gel</td>
+  <td class=xl6913667 width=168 style='width:126pt'>0.129</td>
+  <td class=xl6913667 width=168 style='width:126pt'>0.257</td>
+ </tr>
+ <tr height=93 style='mso-height-source:userset;height:69.95pt'>
+  <td height=93 class=xl6713667 width=172 style='height:69.95pt;width:129pt'>F24H,
+  T59R</td>
+  <td class=xl6513667 width=297 style='width:223pt'>Point mutation at residues
+and 59 on CapDCPfrom Phenylalanine to Histidine and Threonine to Arginine,
+  respectively. Foldit-created linker, Circular Permutation, No Signal
+  Sequence, Single band on protein agarose gel</td>
+  <td class=xl6813667 width=168 style='width:126pt'>0.011</td>
+  <td class=xl6813667 width=168 style='width:126pt'>0.005</td>
+ </tr>
+ <tr height=93 style='mso-height-source:userset;height:69.95pt'>
+  <td height=93 class=xl6613667 width=172 style='height:69.95pt;width:129pt'>F24H,T59N</td>
+  <td class=xl6513667 width=297 style='width:223pt'>Point mutation at residues
+and 59 on CapDCP from Phenylalanine to Histidine and Threonine to
+  Asparagine, respectively. Foldit-created linker, Circular Permutation, No
+  Signal Sequence, Single band on protein agarose gel</td>
+  <td class=xl6913667 width=168 style='width:126pt'>0.007</td>
+  <td class=xl6913667 width=168 style='width:126pt'>0.029</td>
+ </tr>
+ <tr height=93 style='mso-height-source:userset;height:69.95pt'>
+  <td height=93 class=xl6713667 width=172 style='height:69.95pt;width:129pt'>F24W</td>
+  <td class=xl6513667 width=297 style='width:223pt'>Point mutation at residue
+on CapDCP from Phenylalanine to Tryptophan. Foldit-created linker,
+  Circular Permutation, No Signal Sequence, Single band on protein agarose gel</td>
+  <td class=xl6813667 width=168 style='width:126pt'>0.006</td>
+  <td class=xl6813667 width=168 style='width:126pt'>0.044</td>
+ </tr>
+ <tr height=93 style='mso-height-source:userset;height:69.95pt'>
+  <td height=93 class=xl6613667 width=172 style='height:69.95pt;width:129pt'>F24Y</td>
+  <td class=xl6513667 width=297 style='width:223pt'>Point mutation at residue
+on CapDCP from Phenylalanine to Tyrosine. Foldit-created linker, Circular
+  Permutation, No Signal Sequence, Single band on protein agarose gel</td>
+  <td class=xl6913667 width=168 style='width:126pt'>0.593</td>
+  <td class=xl6913667 width=168 style='width:126pt'>0.887</td>
+ </tr>
+ <tr height=93 style='mso-height-source:userset;height:69.95pt'>
+  <td height=93 class=xl6713667 width=172 style='height:69.95pt;width:129pt'>F24Y,
+  L40R</td>
+  <td class=xl6513667 width=297 style='width:223pt'>Point mutation at residues
+and 40 on CapDCP from Phenylalanine to Tyrosine and Leucine to Arginine,
+  respectively. Foldit-created linker, Circular Permutation, No Signal
+  Sequence, Single band on protein agarose gel</td>
+  <td class=xl6813667 width=168 style='width:126pt'>0.009</td>
+  <td class=xl6813667 width=168 style='width:126pt'>-0.013</td>
+ </tr>
+ <tr height=93 style='mso-height-source:userset;height:69.95pt'>
+  <td height=93 class=xl6713667 width=172 style='height:69.95pt;width:129pt'>F24Y,
+  L40R, T59N</td>
+  <td class=xl6513667 width=297 style='width:223pt'>Point mutation at residues
+, 40, 59 on CapDCP from Phenylalanine to Tyrosine, Leucine to
+  Arginine,<span style='mso-spacerun:yes'>  </span>and Threonine to Asparagine,
+  respectively. Foldit-created linker, Circular Permutation, No Signal
+  Sequence, Single band on protein agarose gel</td>
+  <td class=xl6813667 width=168 style='width:126pt'>0.003</td>
+  <td class=xl6813667 width=168 style='width:126pt'>0.157</td>
+ </tr>
+ <tr height=93 style='mso-height-source:userset;height:69.95pt'>
+  <td height=93 class=xl6613667 width=172 style='height:69.95pt;width:129pt'>F24Y,R305K</td>
+  <td class=xl6513667 width=297 style='width:223pt'>Point mutation at residues
+and 305 on CapDCP from Phenylalanine to Tyrosine and Arginine to Lysine,
+  respectively. Foldit-created linker, Circular Permutation, No Signal
+  Sequence, Single band on protein agarose gel</td>
+  <td class=xl6913667 width=168 style='width:126pt'>0.002</td>
+  <td class=xl6913667 width=168 style='width:126pt'>0.233</td>
+ </tr>
+ <tr height=93 style='mso-height-source:userset;height:69.95pt'>
+  <td height=93 class=xl6613667 width=172 style='height:69.95pt;width:129pt'>F24Y,T59N</td>
+  <td class=xl6513667 width=297 style='width:223pt'>Point mutation at residues
+and 59 on CapDCP from Phenylalanine to Tyrosine and Threonine to
+  Asparagine, respectively. Foldit-created linker, Circular Permutation, No
+  Signal Sequence, Single band on protein agarose gel</td>
+  <td class=xl6913667 width=168 style='width:126pt'>0.008</td>
+  <td class=xl6913667 width=168 style='width:126pt'>0.165</td>
+ </tr>
+ <tr height=93 style='mso-height-source:userset;height:69.95pt'>
+  <td height=93 class=xl6613667 width=172 style='height:69.95pt;width:129pt'>F24Y,T59N,R305K</td>
+  <td class=xl6513667 width=297 style='width:223pt'>Point mutation at residues
+, 59, and 356 on CapDCP from Phenylalanine to Tyrosine, Threonine to
+  Asparagine, and Arginine to Lysine, respectively. Foldit-created linker,
+  Circular Permutation, No Signal Sequence, Single band on protein agarose gel</td>
+  <td class=xl6913667 width=168 style='width:126pt'>0.002</td>
+  <td class=xl6913667 width=168 style='width:126pt'>0.127</td>
+ </tr>
+ <tr height=93 style='mso-height-source:userset;height:69.95pt'>
+  <td height=93 class=xl6713667 width=172 style='height:69.95pt;width:129pt'>F60W</td>
+  <td class=xl6513667 width=297 style='width:223pt'>Point mutation at residue
+on CapDCP from Phenylalanine to Tryptophan. Foldit-created linker,
+  Circular Permutation, No Signal Sequence, Single band on protein agarose gel</td>
+  <td class=xl6813667 width=168 style='width:126pt'>0.239</td>
+  <td class=xl6813667 width=168 style='width:126pt'>0.489</td>
+ </tr>
+ <tr height=93 style='mso-height-source:userset;height:69.95pt'>
+  <td height=93 class=xl6613667 width=172 style='height:69.95pt;width:129pt'>G79A</td>
+  <td class=xl6513667 width=297 style='width:223pt'>Point mutation at residue
+on CapDCP from Glycine to Alanine. Foldit-created linker, Circular
+  Permutation, No Signal Sequence, Single band on protein agarose gel</td>
+  <td class=xl6913667 width=168 style='width:126pt'>0.040</td>
+  <td class=xl6913667 width=168 style='width:126pt'>-0.511</td>
+ </tr>
+ <tr height=93 style='mso-height-source:userset;height:69.95pt'>
+  <td height=93 class=xl6613667 width=172 style='height:69.95pt;width:129pt'>I83T</td>
+  <td class=xl6513667 width=297 style='width:223pt'>Point mutation at residue
+on CapDCP from Isoleucine to Threonine. Foldit-created linker, Circular
+  Permutation, No Signal Sequence, Single band on protein agarose gel</td>
+  <td class=xl6913667 width=168 style='width:126pt'>0.009</td>
+  <td class=xl6913667 width=168 style='width:126pt'>0.006</td>
+ </tr>
+ <tr height=93 style='mso-height-source:userset;height:69.95pt'>
+  <td height=93 class=xl6613667 width=172 style='height:69.95pt;width:129pt'>I83V</td>
+  <td class=xl6513667 width=297 style='width:223pt'>Point mutation at residue
+on CapDCP from Isoleucine to Valine. Foldit-created linker, Circular
+  Permutation, No Signal Sequence, Single band on protein agarose gel</td>
+  <td class=xl6913667 width=168 style='width:126pt'>0.003</td>
+  <td class=xl6913667 width=168 style='width:126pt'>0.043</td>
+ </tr>
+ <tr height=93 style='mso-height-source:userset;height:69.95pt'>
+  <td height=93 class=xl6613667 width=172 style='height:69.95pt;width:129pt'>L40A</td>
+  <td class=xl6513667 width=297 style='width:223pt'>Point mutation at residue
+on CapDCP from Leucine to Alanine. Foldit-created linker, Circular
+  Permutation, No Signal Sequence, Single band on protein agarose gel</td>
+  <td class=xl6913667 width=168 style='width:126pt'>0.150</td>
+  <td class=xl6913667 width=168 style='width:126pt'>0.413</td>
+ </tr>
+ <tr height=93 style='mso-height-source:userset;height:69.95pt'>
+  <td height=93 class=xl6613667 width=172 style='height:69.95pt;width:129pt'>L40R</td>
+  <td class=xl6513667 width=297 style='width:223pt'>Point mutation at residue
+on CapDCP from Leucine to Arginine. Foldit-created linker, Circular
+  Permutation, No Signal Sequence, Single band on protein agarose gel</td>
+  <td class=xl6913667 width=168 style='width:126pt'>1.157</td>
+  <td class=xl6913667 width=168 style='width:126pt'>1.527</td>
+ </tr>
+ <tr height=93 style='mso-height-source:userset;height:69.95pt'>
+  <td height=93 class=xl6613667 width=172 style='height:69.95pt;width:129pt'>L40S</td>
+  <td class=xl6513667 width=297 style='width:223pt'>Point mutation at residue
+on CapDCP from Leucine to Serine. Foldit-created linker, Circular
+  Permutation, No Signal Sequence, Single band on protein agarose gel</td>
+  <td class=xl6913667 width=168 style='width:126pt'>0.166</td>
+  <td class=xl6913667 width=168 style='width:126pt'>0.577</td>
+ </tr>
+ <tr height=93 style='mso-height-source:userset;height:69.95pt'>
+  <td height=93 class=xl6613667 width=172 style='height:69.95pt;width:129pt'>L40W</td>
+  <td class=xl6513667 width=297 style='width:223pt'>Point mutation at residue
+on CapDCP from Leucine to Tryptophan. Foldit-created linker, Circular
+  Permutation, No Signal Sequence, Single band on protein agarose gel</td>
+  <td class=xl6913667 width=168 style='width:126pt'>0.825</td>
+  <td class=xl6913667 width=168 style='width:126pt'>1.215</td>
+ </tr>
+ <tr height=93 style='mso-height-source:userset;height:69.95pt'>
+  <td height=93 class=xl6613667 width=172 style='height:69.95pt;width:129pt'>M61H</td>
+  <td class=xl6513667 width=297 style='width:223pt'>Point mutation at residue
+on CapDCP from Methionine to Histidine. Foldit-created linker, Circular
+  Permutation, No Signal Sequence, Single band on protein agarose gel</td>
+  <td class=xl6913667 width=168 style='width:126pt'>-0.003</td>
+  <td class=xl6913667 width=168 style='width:126pt'>0.002</td>
+ </tr>
+ <tr height=93 style='mso-height-source:userset;height:69.95pt'>
+  <td height=93 class=xl6613667 width=172 style='height:69.95pt;width:129pt'>M61N</td>
+  <td class=xl6513667 width=297 style='width:223pt'>Point mutation at residue
+on CapDCP from Methionine to Asparagine. Foldit-created linker, Circular
+  Permutation, No Signal Sequence, Single band on protein agarose gel</td>
+  <td class=xl6913667 width=168 style='width:126pt'>0.011</td>
+  <td class=xl6913667 width=168 style='width:126pt'>0.002</td>
+ </tr>
+ <tr height=93 style='mso-height-source:userset;height:69.95pt'>
+  <td height=93 class=xl6613667 width=172 style='height:69.95pt;width:129pt'>M61S</td>
+  <td class=xl6513667 width=297 style='width:223pt'>Point mutation at residue
+on CapDCP from Methionine to Serine. Foldit-created linker, Circular
+  Permutation, No Signal Sequence, Single band on protein agarose gel</td>
+  <td class=xl6913667 width=168 style='width:126pt'>0.262</td>
+  <td class=xl6913667 width=168 style='width:126pt'>0.485</td>
+ </tr>
+ <tr height=93 style='mso-height-source:userset;height:69.95pt'>
+  <td height=93 class=xl6613667 width=172 style='height:69.95pt;width:129pt'>N23K</td>
+  <td class=xl6513667 width=297 style='width:223pt'>Point mutation at residue
+on CapDCP from Asparagine to Lysine. Foldit-created linker, Circular
+  Permutation, No Signal Sequence, Single band on protein agarose gel</td>
+  <td class=xl6913667 width=168 style='width:126pt'>0.818</td>
+  <td class=xl6913667 width=168 style='width:126pt'>0.839</td>
+ </tr>
+ <tr height=93 style='mso-height-source:userset;height:69.95pt'>
+  <td height=93 class=xl6613667 width=172 style='height:69.95pt;width:129pt'>N23Q</td>
+  <td class=xl6513667 width=297 style='width:223pt'>Point mutation at residue
+on CapDCP from Asparagine to Glutamine. Foldit-created linker, Circular
+  Permutation, No Signal Sequence, Single band on protein agarose gel</td>
+  <td class=xl6913667 width=168 style='width:126pt'>0.165</td>
+  <td class=xl6913667 width=168 style='width:126pt'>0.646</td>
+ </tr>
+ <tr height=93 style='mso-height-source:userset;height:69.95pt'>
+  <td height=93 class=xl6613667 width=172 style='height:69.95pt;width:129pt'>S143K</td>
+  <td class=xl6513667 width=297 style='width:223pt'>Point mutation at residue
+on CapDCP from Serine to Lysine. Foldit-created linker, Circular
+  Permutation, No Signal Sequence, Single band on protein agarose gel</td>
+  <td class=xl6913667 width=168 style='width:126pt'>0.574</td>
+  <td class=xl6913667 width=168 style='width:126pt'>0.426</td>
+ </tr>
+ <tr height=93 style='mso-height-source:userset;height:69.95pt'>
+  <td height=93 class=xl6613667 width=172 style='height:69.95pt;width:129pt'>S22I,
+  T59A</td>
+  <td class=xl6513667 width=297 style='width:223pt'>Point mutation at residues
+and 59 on CapDCP from Serine to Isoleucine and Threonine to Alanine,
+  respectively. Foldit-created linker, Circular Permutation, No Signal
+  Sequence, Single band on protein agarose gel</td>
+  <td class=xl6913667 width=168 style='width:126pt'>0.030</td>
+  <td class=xl6913667 width=168 style='width:126pt'>-0.057</td>
+ </tr>
+ <tr height=93 style='mso-height-source:userset;height:69.95pt'>
+  <td height=93 class=xl6613667 width=172 style='height:69.95pt;width:129pt'>S22Q,
+  T59Q</td>
+  <td class=xl6513667 width=297 style='width:223pt'>Point mutation at residues
+and 59 on CapDCP from Serine to Glutamine and Threonine to Glutamine,
+  respectively. Foldit-created linker, Circular Permutation, No Signal
+  Sequence, Single band on protein agarose gel</td>
+  <td class=xl6913667 width=168 style='width:126pt'>-0.012</td>
+  <td class=xl6913667 width=168 style='width:126pt'>0.085</td>
+ </tr>
+ <tr height=93 style='mso-height-source:userset;height:69.95pt'>
+  <td height=93 class=xl6613667 width=172 style='height:69.95pt;width:129pt'>S57H,
+  M61H</td>
+  <td class=xl6513667 width=297 style='width:223pt'>Point mutation at residues
+and 61 on CapDCP from Serine to Histidine and Methionine to Histidine,
+  respectively. Foldit-created linker, Circular Permutation, No Signal
+  Sequence, Single band on protein agarose gel</td>
+  <td class=xl6913667 width=168 style='width:126pt'>-0.004</td>
+  <td class=xl6913667 width=168 style='width:126pt'>-0.007</td>
+ </tr>
+ <tr height=93 style='mso-height-source:userset;height:69.95pt'>
+  <td height=93 class=xl6613667 width=172 style='height:69.95pt;width:129pt'>T18L,
+  T59Q, M61N, F452W</td>
+  <td class=xl6513667 width=297 style='width:223pt'>Point mutation at residues
+, 59, 61, and 452 on CapDCP from Threonine to Leucine, Threonine to
+  Glutamine, Methionine to Asparagine, and Phenylalanine to Tryptophan,<span
+  style='mso-spacerun:yes'>  </span>respectively. Foldit-created linker,
+  Circular Permutation, No Signal Sequence, Single band on protein agarose gel</td>
+  <td class=xl6913667 width=168 style='width:126pt'>0.020</td>
+  <td class=xl6913667 width=168 style='width:126pt'>-0.028</td>
+ </tr>
+ <tr height=93 style='mso-height-source:userset;height:69.95pt'>
+  <td height=93 class=xl6613667 width=172 style='height:69.95pt;width:129pt'>T18S_T20S</td>
+  <td class=xl6513667 width=297 style='width:223pt'>Point mutation at residues
+and 20 on CapDCP from Threonine to Serine and Threonine to Serine,<span
+  style='mso-spacerun:yes'>  </span>respectively. Foldit-created linker,
+  Circular Permutation, No Signal Sequence, Single band on protein agarose gel</td>
+  <td class=xl6913667 width=168 style='width:126pt'>0.617</td>
+  <td class=xl6913667 width=168 style='width:126pt'>1.186</td>
+ </tr>
+ <tr height=93 style='mso-height-source:userset;height:69.95pt'>
+  <td height=93 class=xl6613667 width=172 style='height:69.95pt;width:129pt'>T20A</td>
+  <td class=xl6513667 width=297 style='width:223pt'>Point mutation at residue
+on CapDCP from Threonine to Alanine. Foldit-created linker, Circular
+  Permutation, No Signal Sequence, Single band on protein agarose gel</td>
+  <td class=xl6913667 width=168 style='width:126pt'>0.011</td>
+  <td class=xl6913667 width=168 style='width:126pt'>0.021</td>
+ </tr>
+ <tr height=93 style='mso-height-source:userset;height:69.95pt'>
+  <td height=93 class=xl6613667 width=172 style='height:69.95pt;width:129pt'>T20C</td>
+  <td class=xl6513667 width=297 style='width:223pt'>Point mutation at residue
+on CapDCP from Threonine to Cystine. Foldit-created linker, Circular
+  Permutation, No Signal Sequence, Single band on protein agarose gel</td>
+  <td class=xl6913667 width=168 style='width:126pt'>0.090</td>
+  <td class=xl6913667 width=168 style='width:126pt'>0.142</td>
+ </tr>
+ <tr height=93 style='mso-height-source:userset;height:69.95pt'>
+  <td height=93 class=xl6613667 width=172 style='height:69.95pt;width:129pt'>T20S</td>
+  <td class=xl6513667 width=297 style='width:223pt'>Point mutation at residue
+on CapDCP from Threonine to Serine. Foldit-created linker, Circular
+  Permutation, No Signal Sequence, Single band on protein agarose gel</td>
+  <td class=xl6913667 width=168 style='width:126pt'>0.639</td>
+  <td class=xl6913667 width=168 style='width:126pt'>1.443</td>
+ </tr>
+ <tr height=93 style='mso-height-source:userset;height:69.95pt'>
+  <td height=93 class=xl6713667 width=172 style='height:69.95pt;width:129pt'>T20S,
+  L40D</td>
+  <td class=xl6513667 width=297 style='width:223pt'>Point mutation at residues
+and 40 on CapDCP from Threonine to Serine and Leucine to Asparagine,
+  respectively. Foldit-created linker, Circular Permutation, No Signal
+  Sequence, Single band on protein agarose gel</td>
+  <td class=xl6813667 width=168 style='width:126pt'>0.853</td>
+  <td class=xl6813667 width=168 style='width:126pt'>0.001</td>
+ </tr>
+ <tr height=93 style='mso-height-source:userset;height:69.95pt'>
+  <td height=93 class=xl6713667 width=172 style='height:69.95pt;width:129pt'>T20S,
+  L40E</td>
+  <td class=xl6513667 width=297 style='width:223pt'>Point mutation at residues
+and 40 on CapDCP from Threonine to Serine and Leucine to Glutamic Acid,
+  respectively. Foldit-created linker, Circular Permutation, No Signal
+  Sequence, Single band on protein agarose gel</td>
+  <td class=xl6813667 width=168 style='width:126pt'>0.163</td>
+  <td class=xl6813667 width=168 style='width:126pt'>0.637</td>
+ </tr>
+ <tr height=93 style='mso-height-source:userset;height:69.95pt'>
+  <td height=93 class=xl6713667 width=172 style='height:69.95pt;width:129pt'>T20S,
+  L40F</td>
+  <td class=xl6513667 width=297 style='width:223pt'>Point mutation at residues
+and 40 on CapDCP from Threonine to Serine and Leucine to Phenylalanine,
+  respectively. Foldit-created linker, Circular Permutation, No Signal
+  Sequence, Single band on protein agarose gel</td>
+  <td class=xl6813667 width=168 style='width:126pt'>0.246</td>
+  <td class=xl6813667 width=168 style='width:126pt'>0.335</td>
+ </tr>
+ <tr height=93 style='mso-height-source:userset;height:69.95pt'>
+  <td height=93 class=xl6713667 width=172 style='height:69.95pt;width:129pt'>T20S,
+  L40H</td>
+  <td class=xl6513667 width=297 style='width:223pt'>Point mutation at residues
+and 40 on CapDCP from Threonine to Serine and Leucine to Histidine,
+  respectively. Foldit-created linker, Circular Permutation, No Signal
+  Sequence, Single band on protein agarose gel</td>
+  <td class=xl6813667 width=168 style='width:126pt'>0.001</td>
+  <td class=xl6813667 width=168 style='width:126pt'>0.012</td>
+ </tr>
+ <tr height=93 style='mso-height-source:userset;height:69.95pt'>
+  <td height=93 class=xl6713667 width=172 style='height:69.95pt;width:129pt'>T20S,
+  L40K</td>
+  <td class=xl6513667 width=297 style='width:223pt'>Point mutation at residues
+and 40 on CapDCP from Threonine to Serine and Leucine to Lysine,
+  respectively. Foldit-created linker, Circular Permutation, No Signal
+  Sequence, Single band on protein agarose gel</td>
+  <td class=xl6813667 width=168 style='width:126pt'>0.000</td>
+  <td class=xl6813667 width=168 style='width:126pt'>0.007</td>
+ </tr>
+ <tr height=93 style='mso-height-source:userset;height:69.95pt'>
+  <td height=93 class=xl6713667 width=172 style='height:69.95pt;width:129pt'>T20S,
+  L40Q</td>
+  <td class=xl6513667 width=297 style='width:223pt'>Point mutation at residues
+and 40 on CapDCP from Threonine to Serine and Leucine to Glutamine,
+  respectively. Foldit-created linker, Circular Permutation, No Signal
+  Sequence, Single band on protein agarose gel</td>
+  <td class=xl6813667 width=168 style='width:126pt'>0.126</td>
+  <td class=xl6813667 width=168 style='width:126pt'>0.478</td>
+ </tr>
+ <tr height=93 style='mso-height-source:userset;height:69.95pt'>
+  <td height=93 class=xl6713667 width=172 style='height:69.95pt;width:129pt'>T20S,
+  L40R</td>
+  <td class=xl6513667 width=297 style='width:223pt'>Point mutation at residues
+and 40 on CapDCP from Threonine to Serine and Leucine to Arginine,
+  respectively. Foldit-created linker, Circular Permutation, No Signal
+  Sequence, Single band on protein agarose gel</td>
+  <td class=xl6813667 width=168 style='width:126pt'>0.000</td>
+  <td class=xl6813667 width=168 style='width:126pt'>0.009</td>
+ </tr>
+ <tr height=93 style='mso-height-source:userset;height:69.95pt'>
+  <td height=93 class=xl6713667 width=172 style='height:69.95pt;width:129pt'>T20S,
+  L40R, F60E</td>
+  <td class=xl6513667 width=297 style='width:223pt'>Point mutation at residues
+, 40, and 60 on CapDCP from Threonine to Serine, Leucine to Arginine, and
+  Phenylalanine to Glutamic Acid, respectively. Foldit-created linker, Circular
+  Permutation, No Signal Sequence, Single band on protein agarose gel</td>
+  <td class=xl6813667 width=168 style='width:126pt'>0.048</td>
+  <td class=xl6813667 width=168 style='width:126pt'>0.028</td>
+ </tr>
+ <tr height=93 style='mso-height-source:userset;height:69.95pt'>
+  <td height=93 class=xl6713667 width=172 style='height:69.95pt;width:129pt'>T20S,
+  L40R, F60Q</td>
+  <td class=xl6513667 width=297 style='width:223pt'>Point mutation at residues
+, 40, and 60 on CapDCP from Threonine to Serine, Leucine to Arginine, and
+  Phenylalanine to Glutamine, respectively. Foldit-created linker, Circular
+  Permutation, No Signal Sequence, Single band on protein agarose gel</td>
+  <td class=xl6813667 width=168 style='width:126pt'>0.002</td>
+  <td class=xl6813667 width=168 style='width:126pt'>0.007</td>
+ </tr>
+ <tr height=93 style='mso-height-source:userset;height:69.95pt'>
+  <td height=93 class=xl6713667 width=172 style='height:69.95pt;width:129pt'>T20S,
+  L40R, N81E</td>
+  <td class=xl6513667 width=297 style='width:223pt'>Point mutation at residues
+, 40, and 60 on CapDCP from Threonine to Serine, Leucine to Arginine, and
+  Phenylalanine to Glutamine, respectively. Foldit-created linker, Circular
+  Permutation, No Signal Sequence, Single band on protein agarose gel</td>
+  <td class=xl6813667 width=168 style='width:126pt'>0.001</td>
+  <td class=xl6813667 width=168 style='width:126pt'>-0.004</td>
+ </tr>
+ <tr height=93 style='mso-height-source:userset;height:69.95pt'>
+  <td height=93 class=xl6713667 width=172 style='height:69.95pt;width:129pt'>T20S,
+  L40R, N81Q</td>
+  <td class=xl6513667 width=297 style='width:223pt'>Point mutation at residues
+, 40, and 81 on CapDCP from Threonine to Serine, Leucine to Arginine, and
+  Asparagine to Glutamine, respectively. Foldit-created linker, Circular
+  Permutation, No Signal Sequence, Single band on protein agarose gel</td>
+  <td class=xl6813667 width=168 style='width:126pt'>0.422</td>
+  <td class=xl6813667 width=168 style='width:126pt'>0.321</td>
+ </tr>
+ <tr height=93 style='mso-height-source:userset;height:69.95pt'>
+  <td height=93 class=xl6713667 width=172 style='height:69.95pt;width:129pt'>T20S,
+  L40R, T59K</td>
+  <td class=xl6513667 width=297 style='width:223pt'>Point mutation at residues
+, 40, and 59 on CapDCP from Threonine to Serine, Leucine to Arginine, and
+  Threonine to Lysine, respectively. Foldit-created linker, Circular
+  Permutation, No Signal Sequence, Single band on protein agarose gel</td>
+  <td class=xl6813667 width=168 style='width:126pt'>0.048</td>
+  <td class=xl6813667 width=168 style='width:126pt'>0.033</td>
+ </tr>
+ <tr height=93 style='mso-height-source:userset;height:69.95pt'>
+  <td height=93 class=xl6713667 width=172 style='height:69.95pt;width:129pt'>T20S,
+  L40R, T59K_M61S</td>
+  <td class=xl6513667 width=297 style='width:223pt'>Point mutation at residues
+, 40, 59, and 61 on CapDCP from Threonine to Serine, Leucine to Arginine,
+  Threonine to Lysine, and Methionine to Serine, respectively. Foldit-created
+  linker, Circular Permutation, No Signal Sequence, Single band on protein agarose
+  gel</td>
+  <td class=xl6813667 width=168 style='width:126pt'>0.010</td>
+  <td class=xl6813667 width=168 style='width:126pt'>0.032</td>
+ </tr>
+ <tr height=93 style='mso-height-source:userset;height:69.95pt'>
+  <td height=93 class=xl6613667 width=172 style='height:69.95pt;width:129pt'>T20S,
+  T59Q, M61T</td>
+  <td class=xl6513667 width=297 style='width:223pt'>Point mutation at residues
+, 59, and 61 on CapDCP from Threonine to Serine, Threonine to Glutamine,
+  and Methionine to Threonine, respectively. Foldit-created linker, Circular
+  Permutation, No Signal Sequence, Single band on protein agarose gel</td>
+  <td class=xl6913667 width=168 style='width:126pt'>0.007</td>
+  <td class=xl6913667 width=168 style='width:126pt'>-0.069</td>
+ </tr>
+ <tr height=93 style='mso-height-source:userset;height:69.95pt'>
+  <td height=93 class=xl6613667 width=172 style='height:69.95pt;width:129pt'>T20S,M61A</td>
+  <td class=xl6513667 width=297 style='width:223pt'>Point mutation at residues
+and 61 on CapDCP from Threonine to Serine and Methionine to Alanine,
+  respectively. Foldit-created linker, Circular Permutation, No Signal
+  Sequence, Single band on protein agarose gel</td>
+  <td class=xl6913667 width=168 style='width:126pt'>0.005</td>
+  <td class=xl6913667 width=168 style='width:126pt'>0.045</td>
+ </tr>
+ <tr height=93 style='mso-height-source:userset;height:69.95pt'>
+  <td height=93 class=xl6613667 width=172 style='height:69.95pt;width:129pt'>T20S,M61C</td>
+  <td class=xl6513667 width=297 style='width:223pt'>Point mutation at residues
+and 61 on CapDCP from Threonine to Serine and Methionine to Cystine,
+  respectively. Foldit-created linker, Circular Permutation, No Signal
+  Sequence, Single band on protein agarose gel</td>
+  <td class=xl6913667 width=168 style='width:126pt'>0.102</td>
+  <td class=xl6913667 width=168 style='width:126pt'>0.207</td>
+ </tr>
+ <tr height=93 style='mso-height-source:userset;height:69.95pt'>
+  <td height=93 class=xl6613667 width=172 style='height:69.95pt;width:129pt'>T20S,M61D</td>
+  <td class=xl6513667 width=297 style='width:223pt'>Point mutation at residues
+and 61 on CapDCP from Threonine to Serine and Methionine to Aspartic Acid,
+  respectively. Foldit-created linker, Circular Permutation, No Signal
+  Sequence, Single band on protein agarose gel</td>
+  <td class=xl6913667 width=168 style='width:126pt'>0.004</td>
+  <td class=xl6913667 width=168 style='width:126pt'>0.003</td>
+ </tr>
+ <tr height=93 style='mso-height-source:userset;height:69.95pt'>
+  <td height=93 class=xl6613667 width=172 style='height:69.95pt;width:129pt'>T20S,M61G</td>
+  <td class=xl6513667 width=297 style='width:223pt'>Point mutation at residues
+and 61 on CapDCP from Threonine to Serine and Methionine to Glycine,
+  respectively. Foldit-created linker, Circular Permutation, No Signal
+  Sequence, Single band on protein agarose gel</td>
+  <td class=xl6913667 width=168 style='width:126pt'>0.004</td>
+  <td class=xl6913667 width=168 style='width:126pt'>0.029</td>
+ </tr>
+ <tr height=93 style='mso-height-source:userset;height:69.95pt'>
+  <td height=93 class=xl6613667 width=172 style='height:69.95pt;width:129pt'>T20S,M61L</td>
+  <td class=xl6513667 width=297 style='width:223pt'>Point mutation at residues
+and 61 on CapDCP from Threonine to Serine and Methionine to Leucine,
+  respectively. Foldit-created linker, Circular Permutation, No Signal
+  Sequence, Single band on protein agarose gel</td>
+  <td class=xl6913667 width=168 style='width:126pt'>0.004</td>
+  <td class=xl6913667 width=168 style='width:126pt'>0.029</td>
+ </tr>
+ <tr height=93 style='mso-height-source:userset;height:69.95pt'>
+  <td height=93 class=xl6613667 width=172 style='height:69.95pt;width:129pt'>T20S,M61N</td>
+  <td class=xl6513667 width=297 style='width:223pt'>Point mutation at residues
+and 61 on CapDCP from Threonine to Serine and Methionine to Asparagine,
+  respectively. Foldit-created linker, Circular Permutation, No Signal
+  Sequence, Single band on protein agarose gel</td>
+  <td class=xl6913667 width=168 style='width:126pt'>0.003</td>
+  <td class=xl6913667 width=168 style='width:126pt'>0.002</td>
+ </tr>
+ <tr height=93 style='mso-height-source:userset;height:69.95pt'>
+  <td height=93 class=xl6613667 width=172 style='height:69.95pt;width:129pt'>T20S,M61S</td>
+  <td class=xl6513667 width=297 style='width:223pt'>Point mutation at residues
+and 61 on CapDCP from Threonine to Serine and Methionine to Serine,
+  respectively. Foldit-created linker, Circular Permutation, No Signal
+  Sequence, Single band on protein agarose gel</td>
+  <td class=xl6913667 width=168 style='width:126pt'>0.007</td>
+  <td class=xl6913667 width=168 style='width:126pt'>0.053</td>
+ </tr>
+ <tr height=93 style='mso-height-source:userset;height:69.95pt'>
+  <td height=93 class=xl6613667 width=172 style='height:69.95pt;width:129pt'>T20S,M61T</td>
+  <td class=xl6513667 width=297 style='width:223pt'>Point mutation at residues
+and 61 on CapDCP from Threonine to Serine and Methionine to Threonine,
+  respectively. Foldit-created linker, Circular Permutation, No Signal
+  Sequence, Single band on protein agarose gel</td>
+  <td class=xl6913667 width=168 style='width:126pt'>0.038</td>
+  <td class=xl6913667 width=168 style='width:126pt'>0.363</td>
+ </tr>
+ <tr height=93 style='mso-height-source:userset;height:69.95pt'>
+  <td height=93 class=xl6613667 width=172 style='height:69.95pt;width:129pt'>T20S,M61V</td>
+  <td class=xl6513667 width=297 style='width:223pt'>Point mutation at residues
+and 61 on CapDCP from Threonine to Serine and Methionine to Valine,
+  respectively. Foldit-created linker, Circular Permutation, No Signal
+  Sequence, Single band on protein agarose gel</td>
+  <td class=xl6913667 width=168 style='width:126pt'>0.004</td>
+  <td class=xl6913667 width=168 style='width:126pt'>0.039</td>
+ </tr>
+ <tr height=93 style='mso-height-source:userset;height:69.95pt'>
+  <td height=93 class=xl6613667 width=172 style='height:69.95pt;width:129pt'>T20S,T59N</td>
+  <td class=xl6513667 width=297 style='width:223pt'>Point mutation at residues
+and 59 on CapDCP from Threonine to Serine and Threonine to Asparagine,
+  respectively. Foldit-created linker, Circular Permutation, No Signal
+  Sequence, Single band on protein agarose gel</td>
+  <td class=xl6913667 width=168 style='width:126pt'>0.019</td>
+  <td class=xl6913667 width=168 style='width:126pt'>0.125</td>
+ </tr>
+ <tr height=93 style='mso-height-source:userset;height:69.95pt'>
+  <td height=93 class=xl6613667 width=172 style='height:69.95pt;width:129pt'>T20S,T59S_M61S</td>
+  <td class=xl6513667 width=297 style='width:223pt'>Point mutation at residues
+, 59, and 61 on CapDCP from Threonine to Serine, Threonine to Serine, and
+  Methionine to Serine, respectively. Foldit-created linker, Circular
+  Permutation, No Signal Sequence, Single band on protein agarose gel</td>
+  <td class=xl6913667 width=168 style='width:126pt'>0.300</td>
+  <td class=xl6913667 width=168 style='width:126pt'>0.719</td>
+ </tr>
+ <tr height=93 style='mso-height-source:userset;height:69.95pt'>
+  <td height=93 class=xl6613667 width=172 style='height:69.95pt;width:129pt'>T20S_F24H</td>
+  <td class=xl6513667 width=297 style='width:223pt'>Point mutation at residues
+and 24 on CapDCP from Threonine to Serine and Phenylalanine to Histidine,
+  respectively. Foldit-created linker, Circular Permutation, No Signal
+  Sequence, Single band on protein agarose gel</td>
+  <td class=xl6913667 width=168 style='width:126pt'>0.008</td>
+  <td class=xl6913667 width=168 style='width:126pt'>0.097</td>
+ </tr>
+ <tr height=93 style='mso-height-source:userset;height:69.95pt'>
+  <td height=93 class=xl6613667 width=172 style='height:69.95pt;width:129pt'>T20S_F24Y</td>
+  <td class=xl6513667 width=297 style='width:223pt'>Point mutation at residues
+and 24 on CapDCP from Threonine to Serine and Phenylalanine to Tyrosine,
+  respectively. Foldit-created linker, Circular Permutation, No Signal
+  Sequence, Single band on protein agarose gel</td>
+  <td class=xl6913667 width=168 style='width:126pt'>0.040</td>
+  <td class=xl6913667 width=168 style='width:126pt'>0.201</td>
+ </tr>
+ <tr height=93 style='mso-height-source:userset;height:69.95pt'>
+  <td height=93 class=xl6613667 width=172 style='height:69.95pt;width:129pt'>T20S_F24Y,T59N</td>
+  <td class=xl6513667 width=297 style='width:223pt'>Point mutation at residues
+, 24, and 59 on CapDCP from Threonine to Serine, Phenylalanine to Tyrosine,
+  and Threonine to Asparagine, respectively. Foldit-created linker, Circular
+  Permutation, No Signal Sequence, Single band on protein agarose gel</td>
+  <td class=xl6913667 width=168 style='width:126pt'>0.013</td>
+  <td class=xl6913667 width=168 style='width:126pt'>0.048</td>
+ </tr>
+ <tr height=93 style='mso-height-source:userset;height:69.95pt'>
+  <td height=93 class=xl6613667 width=172 style='height:69.95pt;width:129pt'>T2A</td>
+  <td class=xl6513667 width=297 style='width:223pt'>Point mutation at residue 2
+  on CapDCP from Threonine to Alanine. Foldit-created linker, Circular
+  Permutation, No Signal Sequence, Single band on protein agarose gel</td>
+  <td class=xl6913667 width=168 style='width:126pt'>0.007</td>
+  <td class=xl6913667 width=168 style='width:126pt'>-0.020</td>
+ </tr>
+ <tr height=93 style='mso-height-source:userset;height:69.95pt'>
+  <td height=93 class=xl6613667 width=172 style='height:69.95pt;width:129pt'>T2C</td>
+  <td class=xl6513667 width=297 style='width:223pt'>Point mutation at residue 2
+  on CapDCP from Threonine to Cystine. Foldit-created linker, Circular
+  Permutation, No Signal Sequence, Single band on protein agarose gel</td>
+  <td class=xl6913667 width=168 style='width:126pt'>0.001</td>
+  <td class=xl6913667 width=168 style='width:126pt'>-0.005</td>
+ </tr>
+ <tr height=93 style='mso-height-source:userset;height:69.95pt'>
+  <td height=93 class=xl6613667 width=172 style='height:69.95pt;width:129pt'>T2S</td>
+  <td class=xl6513667 width=297 style='width:223pt'>Point mutation at residue 2
+  on CapDCP from Threonine to Serine. Foldit-created linker, Circular
+  Permutation, No Signal Sequence, Single band on protein agarose gel</td>
+  <td class=xl6913667 width=168 style='width:126pt'>0.024</td>
+  <td class=xl6913667 width=168 style='width:126pt'>0.325</td>
+ </tr>
+ <tr height=93 style='mso-height-source:userset;height:69.95pt'>
+  <td height=93 class=xl6613667 width=172 style='height:69.95pt;width:129pt'>T2S,T18S_T20S</td>
+  <td class=xl6513667 width=297 style='width:223pt'>Point mutation at residues
+, 18, and 20 on CapDCP from Threonine to Serine, Threonine to Serine, and
+  Threonine to Serine, respectively. Foldit-created linker, Circular
+  Permutation, No Signal Sequence, Single band on protein agarose gel</td>
+  <td class=xl6913667 width=168 style='width:126pt'>0.144</td>
+  <td class=xl6913667 width=168 style='width:126pt'>0.250</td>
+ </tr>
+ <tr height=93 style='mso-height-source:userset;height:69.95pt'>
+  <td height=93 class=xl6613667 width=172 style='height:69.95pt;width:129pt'>T2S,T18S_T20S,T59S_M61S</td>
+  <td class=xl6513667 width=297 style='width:223pt'>Point mutation at residues
+, 18, 20, 59, and 61 on CapDCP from Threonine to Serine, Threonine to
+  Serine, Threonine to Serine, Threonine to Serine and Threonine to Serine,
+  respectively. Foldit-created linker, Circular Permutation, No Signal
+  Sequence, Single band on protein agarose gel</td>
+  <td class=xl6913667 width=168 style='width:126pt'>0.003</td>
+  <td class=xl6913667 width=168 style='width:126pt'>0.022</td>
+ </tr>
+ <tr height=93 style='mso-height-source:userset;height:69.95pt'>
+  <td height=93 class=xl6613667 width=172 style='height:69.95pt;width:129pt'>T2S,T20S</td>
+  <td class=xl6513667 width=297 style='width:223pt'>Point mutation at residues
+and 20 on CapDCP from Threonine to Serine and Threonine to Serine,
+  respectively. Foldit-created linker, Circular Permutation, No Signal
+  Sequence, Single band on protein agarose gel</td>
+  <td class=xl6913667 width=168 style='width:126pt'>0.106</td>
+  <td class=xl6913667 width=168 style='width:126pt'>0.089</td>
+ </tr>
+ <tr height=93 style='mso-height-source:userset;height:69.95pt'>
+  <td height=93 class=xl6613667 width=172 style='height:69.95pt;width:129pt'>T2V</td>
+  <td class=xl6513667 width=297 style='width:223pt'>Point mutation at residue 2
+  on CapDCP from Threonine to Valine. Foldit-created linker, Circular
+  Permutation, No Signal Sequence, Single band on protein agarose gel</td>
+  <td class=xl6913667 width=168 style='width:126pt'>0.000</td>
+  <td class=xl6913667 width=168 style='width:126pt'>0.000</td>
+ </tr>
+ <tr height=93 style='mso-height-source:userset;height:69.95pt'>
+  <td height=93 class=xl6613667 width=172 style='height:69.95pt;width:129pt'>T59H_M61A</td>
+  <td class=xl6513667 width=297 style='width:223pt'>Point mutation at residues
+and 61 on CapDCP from Threonine to Histidine and Methionine to Alanine,
+  respectively. Foldit-created linker, Circular Permutation, No Signal
+  Sequence, Single band on protein agarose gel</td>
+  <td class=xl6913667 width=168 style='width:126pt'>0.000</td>
+  <td class=xl6913667 width=168 style='width:126pt'>0.000</td>
+ </tr>
+ <tr height=93 style='mso-height-source:userset;height:69.95pt'>
+  <td height=93 class=xl6613667 width=172 style='height:69.95pt;width:129pt'>T59H_M61T</td>
+  <td class=xl6513667 width=297 style='width:223pt'>Point mutation at residues
+and 61 on CapDCP from Threonine to Histidine and Methionine to Threonine,
+  respectively. Foldit-created linker, Circular Permutation, No Signal
+  Sequence, Single band on protein agarose gel</td>
+  <td class=xl6913667 width=168 style='width:126pt'>0.000</td>
+  <td class=xl6913667 width=168 style='width:126pt'>0.000</td>
+ </tr>
+ <tr height=93 style='mso-height-source:userset;height:69.95pt'>
+  <td height=93 class=xl6613667 width=172 style='height:69.95pt;width:129pt'>T59M</td>
+  <td class=xl6513667 width=297 style='width:223pt'>Point mutation at residue
+on CapDCP from Threonine to Methionine. Foldit-created linker, Circular
+  Permutation, No Signal Sequence, Single band on protein agarose gel</td>
+  <td class=xl6913667 width=168 style='width:126pt'>0.008</td>
+  <td class=xl6913667 width=168 style='width:126pt'>0.008</td>
+ </tr>
+ <tr height=93 style='mso-height-source:userset;height:69.95pt'>
+  <td height=93 class=xl6613667 width=172 style='height:69.95pt;width:129pt'>T59N</td>
+  <td class=xl6513667 width=297 style='width:223pt'>Point mutation at residue
+on CapDCP from Threonine to Asparagine. Foldit-created linker, Circular
+  Permutation, No Signal Sequence, Single band on protein agarose gel</td>
+  <td class=xl6913667 width=168 style='width:126pt'>0.232</td>
+  <td class=xl6913667 width=168 style='width:126pt'>0.868</td>
+ </tr>
+ <tr height=93 style='mso-height-source:userset;height:69.95pt'>
+  <td height=93 class=xl6613667 width=172 style='height:69.95pt;width:129pt'>T59Q</td>
+  <td class=xl6513667 width=297 style='width:223pt'>Point mutation at residue
+on CapDCP from Threonine to Glutamine. Foldit-created linker, Circular
+  Permutation, No Signal Sequence, Single band on protein agarose gel</td>
+  <td class=xl6913667 width=168 style='width:126pt'>0.000</td>
+  <td class=xl6913667 width=168 style='width:126pt'>0.000</td>
+ </tr>
+ <tr height=93 style='mso-height-source:userset;height:69.95pt'>
+  <td height=93 class=xl6613667 width=172 style='height:69.95pt;width:129pt'>T59Q,
+  M61Q, F452W</td>
+  <td class=xl6513667 width=297 style='width:223pt'>Point mutation at residues
+, 61, and 452 on CapDCP from Threonine to Glutamine, Threonine to
+  Glutamine, and Phenylalanine to Tryptophan, respectively. Foldit-created
+  linker, Circular Permutation, No Signal Sequence, Single band on protein
+  agarose gel</td>
+  <td class=xl6913667 width=168 style='width:126pt'>-0.014</td>
+  <td class=xl6913667 width=168 style='width:126pt'>0.037</td>
+ </tr>
+ <tr height=93 style='mso-height-source:userset;height:69.95pt'>
+  <td height=93 class=xl6613667 width=172 style='height:69.95pt;width:129pt'>T59S</td>
+  <td class=xl6513667 width=297 style='width:223pt'>Point mutation at residue
+on CapDCP from Threonine to Serine. Foldit-created linker, Circular
+  Permutation, No Signal Sequence, Single band on protein agarose gel</td>
+  <td class=xl6913667 width=168 style='width:126pt'>3.525</td>
+  <td class=xl6913667 width=168 style='width:126pt'>1.047</td>
+ </tr>
+ <tr height=93 style='mso-height-source:userset;height:69.95pt'>
+  <td height=93 class=xl6613667 width=172 style='height:69.95pt;width:129pt'>T59S,
+  M61H</td>
+  <td class=xl6513667 width=297 style='width:223pt'>Point mutation at residues
+and 61 on CapDCP from Threonine to Serine and Methionine to Histidine,
+  respectively. Foldit-created linker, Circular Permutation, No Signal
+  Sequence, Single band on protein agarose gel</td>
+  <td class=xl6913667 width=168 style='width:126pt'>0.013</td>
+  <td class=xl6913667 width=168 style='width:126pt'>0.051</td>
+ </tr>
+ <![if supportMisalignedColumns]>
+ <tr height=0 style='display:none'>
+  <td width=172 style='width:129pt'></td>
+  <td width=297 style='width:223pt'></td>
+  <td width=168 style='width:126pt'></td>
+  <td width=168 style='width:126pt'></td>
+ </tr>
+ <![endif]>
+</table>
+</div>
- var c_rgszClr=new Array(8);
- c_rgszClr[0]="window";
- c_rgszClr[1]="buttonface";
- c_rgszClr[2]="windowframe";
- c_rgszClr[3]="windowtext";
- c_rgszClr[4]="threedlightshadow";
- c_rgszClr[5]="threedhighlight";
- c_rgszClr[6]="threeddarkshadow";
- c_rgszClr[7]="threedshadow";
- var g_iShCur;
+<!----------------------------->
- var g_rglTabX=new Array(c_lTabs);
+<!--END OF OUTPUT FROM EXCEL PUBLISH AS WEB PAGE WIZARD-->
+<!----------------------------->
+</body>
-function fnGetIEVer()
+</html>
-{
+<!---------------------------------------PAGE CONTENT GOES ABOVE THIS---------------------------------------->
- var ua=window.navigator.userAgent
- var msie=ua.indexOf("MSIE")
- if (msie>0 && window.navigator.platform=="Win32")
-  return parseInt(ua.substring(msie+5,ua.indexOf(".", msie)));
- else
-  return 0;
-}
-function fnBuildFrameset()
+<div style="text-align:center">
-{
+'''&larr; [[Team:Washington/Gram_Positive/Test|Back to Testing the Gram(+) Therapeutic]]'''
- var szHTML="<frameset rows=\"*,18\" border=0 width=0 frameborder=no framespacing=0>"+
+&nbsp; &nbsp; &nbsp;
-  "<frame src=\""+document.all.item("shLink")[0].href+"\" name=\"frSheet\" noresize>"+
+</div>
-  "<frameset cols=\"54,*\" border=0 width=0 frameborder=no framespacing=0>"+
-  "<frame src=\"\" name=\"frScroll\" marginwidth=0 marginheight=0 scrolling=no>"+
-  "<frame src=\"\" name=\"frTabs\" marginwidth=0 marginheight=0 scrolling=no>"+
-  "</frameset></frameset><plaintext>";
- with (document) {
-  open("text/html","replace");
-  write(szHTML);
-  close();
- }
- fnBuildTabStrip();
-}
-function fnBuildTabStrip()
-{
- var szHTML=
-  "<html><head><style>.clScroll {font:8pt Courier New;color:"+c_rgszClr[6]+";cursor:default;line-height:10pt;}"+
-  ".clScroll2 {font:10pt Arial;color:"+c_rgszClr[6]+";cursor:default;line-height:11pt;}</style></head>"+
-  "<body onclick=\"event.returnValue=false;\" ondragstart=\"event.returnValue=false;\" onselectstart=\"event.returnValue=false;\" bgcolor="+c_rgszClr[4]+" topmargin=0 leftmargin=0><table cellpadding=0 cellspacing=0 width=100%>"+
-  "<tr><td colspan=6 height=1 bgcolor="+c_rgszClr[2]+"></td></tr>"+
-  "<tr><td style=\"font:1pt\">&nbsp;<td>"+
-  "<td valign=top id=tdScroll class=\"clScroll\" onclick=\"parent.fnFastScrollTabs(0);\" onmouseover=\"parent.fnMouseOverScroll(0);\" onmouseout=\"parent.fnMouseOutScroll(0);\"><a>&#171;</a></td>"+
-  "<td valign=top id=tdScroll class=\"clScroll2\" onclick=\"parent.fnScrollTabs(0);\" ondblclick=\"parent.fnScrollTabs(0);\" onmouseover=\"parent.fnMouseOverScroll(1);\" onmouseout=\"parent.fnMouseOutScroll(1);\"><a>&lt</a></td>"+
-  "<td valign=top id=tdScroll class=\"clScroll2\" onclick=\"parent.fnScrollTabs(1);\" ondblclick=\"parent.fnScrollTabs(1);\" onmouseover=\"parent.fnMouseOverScroll(2);\" onmouseout=\"parent.fnMouseOutScroll(2);\"><a>&gt</a></td>"+
-  "<td valign=top id=tdScroll class=\"clScroll\" onclick=\"parent.fnFastScrollTabs(1);\" onmouseover=\"parent.fnMouseOverScroll(3);\" onmouseout=\"parent.fnMouseOutScroll(3);\"><a>&#187;</a></td>"+
-  "<td style=\"font:1pt\">&nbsp;<td></tr></table></body></html>";
- with (frames['frScroll'].document) {
-  open("text/html","replace");
-  write(szHTML);
-  close();
- }
- szHTML =
-  "<html><head>"+
-  "<style>A:link,A:visited,A:active {text-decoration:none;"+"color:"+c_rgszClr[3]+";}"+
-  ".clTab {cursor:hand;background:"+c_rgszClr[1]+";font:9pt Arial;padding-left:3px;padding-right:3px;text-align:center;}"+
-  ".clBorder {background:"+c_rgszClr[2]+";font:1pt;}"+
-  "</style></head><body onload=\"parent.fnInit();\" onselectstart=\"event.returnValue=false;\" ondragstart=\"event.returnValue=false;\" bgcolor="+c_rgszClr[4]+
-  " topmargin=0 leftmargin=0><table id=tbTabs cellpadding=0 cellspacing=0>";
- var iCellCount=(c_lTabs+1)*2;
- var i;
- for (i=0;i<iCellCount;i+=2)
-  szHTML+="<col width=1><col>";
- var iRow;
- for (iRow=0;iRow<6;iRow++) {
-  szHTML+="<tr>";
-  if (iRow==5)
-   szHTML+="<td colspan="+iCellCount+"></td>";
-  else {
-   if (iRow==0) {
-    for(i=0;i<iCellCount;i++)
-     szHTML+="<td height=1 class=\"clBorder\"></td>";
-   } else if (iRow==1) {
-    for(i=0;i<c_lTabs;i++) {
-     szHTML+="<td height=1 nowrap class=\"clBorder\">&nbsp;</td>";
-     szHTML+=
-      "<td id=tdTab height=1 nowrap class=\"clTab\" onmouseover=\"parent.fnMouseOverTab("+i+");\" onmouseout=\"parent.fnMouseOutTab("+i+");\">"+
-      "<a href=\""+document.all.item("shLink")[i].href+"\" target=\"frSheet\" id=aTab>&nbsp;"+c_rgszSh[i]+"&nbsp;</a></td>";
-    }
-    szHTML+="<td id=tdTab height=1 nowrap class=\"clBorder\"><a id=aTab>&nbsp;</a></td><td width=100%></td>";
-   } else if (iRow==2) {
-    for (i=0;i<c_lTabs;i++)
-     szHTML+="<td height=1></td><td height=1 class=\"clBorder\"></td>";
-    szHTML+="<td height=1></td><td height=1></td>";
-   } else if (iRow==3) {
-    for (i=0;i<iCellCount;i++)
-     szHTML+="<td height=1></td>";
-   } else if (iRow==4) {
-    for (i=0;i<c_lTabs;i++)
-     szHTML+="<td height=1 width=1></td><td height=1></td>";
-    szHTML+="<td height=1 width=1></td><td></td>";
-   }
-  }
-  szHTML+="</tr>";
- }
- szHTML+="</table></body></html>";
- with (frames['frTabs'].document) {
-  open("text/html","replace");
-  charset=document.charset;
-  write(szHTML);
-  close();
- }
-}
-function fnInit()
-{
- g_rglTabX[0]=0;
- var i;
- for (i=1;i<=c_lTabs;i++)
-  with (frames['frTabs'].document.all.tbTabs.rows[1].cells[fnTabToCol(i-1)])
-   g_rglTabX[i]=offsetLeft+offsetWidth-6;
-}
-function fnTabToCol(iTab)
-{
- return 2*iTab+1;
-}
-function fnNextTab(fDir)
-{
- var iNextTab=-1;
- var i;
- with (frames['frTabs'].document.body) {
-  if (fDir==0) {
-   if (scrollLeft>0) {
-    for (i=0;i<c_lTabs&&g_rglTabX[i]<scrollLeft;i++);
-    if (i<c_lTabs)
-     iNextTab=i-1;
-   }
-  } else {
-   if (g_rglTabX[c_lTabs]+6>offsetWidth+scrollLeft) {
-    for (i=0;i<c_lTabs&&g_rglTabX[i]<=scrollLeft;i++);
-    if (i<c_lTabs)
-     iNextTab=i;
-   }
-  }
- }
- return iNextTab;
-}
-function fnScrollTabs(fDir)
-{
- var iNextTab=fnNextTab(fDir);
- if (iNextTab>=0) {
-  frames['frTabs'].scroll(g_rglTabX[iNextTab],0);
-  return true;
- } else
-  return false;
-}
-function fnFastScrollTabs(fDir)
-{
- if (c_lTabs>16)
-  frames['frTabs'].scroll(g_rglTabX[fDir?c_lTabs-1:0],0);
- else
-  if (fnScrollTabs(fDir)>0) window.setTimeout("fnFastScrollTabs("+fDir+");",5);
-}
-function fnSetTabProps(iTab,fActive)
-{
- var iCol=fnTabToCol(iTab);
- var i;
- if (iTab>=0) {
-  with (frames['frTabs'].document.all) {
-   with (tbTabs) {
-    for (i=0;i<=4;i++) {
-     with (rows[i]) {
-      if (i==0)
-       cells[iCol].style.background=c_rgszClr[fActive?0:2];
-      else if (i>0 && i<4) {
-       if (fActive) {
-        cells[iCol-1].style.background=c_rgszClr[2];
-        cells[iCol].style.background=c_rgszClr[0];
-        cells[iCol+1].style.background=c_rgszClr[2];
-       } else {
-        if (i==1) {
-         cells[iCol-1].style.background=c_rgszClr[2];
-         cells[iCol].style.background=c_rgszClr[1];
-         cells[iCol+1].style.background=c_rgszClr[2];
-        } else {
-         cells[iCol-1].style.background=c_rgszClr[4];
-         cells[iCol].style.background=c_rgszClr[(i==2)?2:4];
-         cells[iCol+1].style.background=c_rgszClr[4];
-        }
-       }
-      } else
-       cells[iCol].style.background=c_rgszClr[fActive?2:4];
-     }
-    }
-   }
-   with (aTab[iTab].style) {
-    cursor=(fActive?"default":"hand");
-    color=c_rgszClr[3];
-   }
-  }
- }
-}
-function fnMouseOverScroll(iCtl)
-{
- frames['frScroll'].document.all.tdScroll[iCtl].style.color=c_rgszClr[7];
-}
-function fnMouseOutScroll(iCtl)
-{
- frames['frScroll'].document.all.tdScroll[iCtl].style.color=c_rgszClr[6];
-}
-function fnMouseOverTab(iTab)
-{
- if (iTab!=g_iShCur) {
-  var iCol=fnTabToCol(iTab);
-  with (frames['frTabs'].document.all) {
-   tdTab[iTab].style.background=c_rgszClr[5];
-  }
- }
-}
-function fnMouseOutTab(iTab)
-{
- if (iTab>=0) {
-  var elFrom=frames['frTabs'].event.srcElement;
-  var elTo=frames['frTabs'].event.toElement;
-  if ((!elTo) ||
-   (elFrom.tagName==elTo.tagName) ||
-   (elTo.tagName=="A" && elTo.parentElement!=elFrom) ||
-   (elFrom.tagName=="A" && elFrom.parentElement!=elTo)) {
-   if (iTab!=g_iShCur) {
-    with (frames['frTabs'].document.all) {
-     tdTab[iTab].style.background=c_rgszClr[1];
-    }
-   }
-  }
- }
-}
-function fnSetActiveSheet(iSh)
-{
- if (iSh!=g_iShCur) {
-  fnSetTabProps(g_iShCur,false);
-  fnSetTabProps(iSh,true);
-  g_iShCur=iSh;
- }
-}
- window.g_iIEVer=fnGetIEVer();
- if (window.g_iIEVer>=4)
-  fnBuildFrameset();
-//-->
-</script>
-<![endif]><!--[if gte mso 9]><xml>
- <x:ExcelWorkbook>
-  <x:ExcelWorksheets>
-   <x:ExcelWorksheet>
-    <x:Name>MutantData Table</x:Name>
-    <x:WorksheetSource HRef="MutantData%20Table_files/sheet001.htm"/>
-   </x:ExcelWorksheet>
-  </x:ExcelWorksheets>
-  <x:Stylesheet HRef="MutantData%20Table_files/stylesheet.css"/>
-  <x:WindowHeight>8505</x:WindowHeight>
-  <x:WindowWidth>18195</x:WindowWidth>
-  <x:WindowTopX>480</x:WindowTopX>
-  <x:WindowTopY>60</x:WindowTopY>
-  <x:ProtectStructure>False</x:ProtectStructure>
-  <x:ProtectWindows>False</x:ProtectWindows>
- </x:ExcelWorkbook>
-</xml><![endif]-->
-</head>
-<frameset rows="*,39" border=0 width=0 frameborder=no framespacing=0>
- <frame src="MutantData%20Table_files/sheet001.htm" name="frSheet">
- <frame src="MutantData%20Table_files/tabstrip.htm" name="frTabs" marginwidth=0 marginheight=0>
- <noframes>
-  <body>
-   <p>This page uses frames, but your browser doesn't support them.</p>
-  </body>
- </noframes>
-</frameset>
-</html>

Team:Washington/DataTable

From 2010.igem.org

Latest revision as of 20:37, 25 October 2010

Mutant Data Table