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Team:Brown/Modeling/ODEs
From 2010.igem.org
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We formulated a system of differential equations which we used to model our system. As we have many players in our system and thus many equations, we chose to combine transcription and translation into single equations representing protein synthesis. | We formulated a system of differential equations which we used to model our system. As we have many players in our system and thus many equations, we chose to combine transcription and translation into single equations representing protein synthesis. | ||
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In all cases the equations represent the change in concentration in nanomoles/minute. | In all cases the equations represent the change in concentration in nanomoles/minute. | ||
Most equations make use of the Hill equation, which is used to model the cooperative binding of a ligand to a molecule. This is accomplished by describing the fraction of bound macromolecule as a function of ligand concentration. | Most equations make use of the Hill equation, which is used to model the cooperative binding of a ligand to a molecule. This is accomplished by describing the fraction of bound macromolecule as a function of ligand concentration. | ||
Revision as of 22:39, 24 October 2010
ODE Modeling of the Quad-State circuit
We formulated a system of differential equations which we used to model our system. As we have many players in our system and thus many equations, we chose to combine transcription and translation into single equations representing protein synthesis.
In all cases the equations represent the change in concentration in nanomoles/minute.
Most equations make use of the Hill equation, which is used to model the cooperative binding of a ligand to a molecule. This is accomplished by describing the fraction of bound macromolecule as a function of ligand concentration.
