Team:Uppsala-SwedenModeling

From 2010.igem.org

(Difference between revisions)
(Results)
(Code)
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== Code ==
== Code ==
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== odeIGEM03.m ==
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  %lambda1 function file
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function dX =odeIGEM02(t,X,P)
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k1=P(1);
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k2=P(2);
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k3=P(3);
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k4=P(4);
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k5=P(5);
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k6=P(6);
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k7=P(7);
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k8=P(8);
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k9=P(9);
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k10=P(10);
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k11=P(11);
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km1=P(12);
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km2=P(13);
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km3=P(14);
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km4=P(15);
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km5=P(16);
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ahl=X(1);
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lam=X(2);
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ci=X(3);
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laci=X(4);
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gfp=X(5);
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n1=1;
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n2=1;
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n3=1;
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n4=1;
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n5=2;
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dlam=((k1*(ahl/km1)^n1)/(1+(ahl/km1)^n1))-k2*lam;
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dahl=0;%k10*ahl-k11*ahl;
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dci=((k3*(lam/km3)^n2)/(1+(lam/km3)^n2))-k4*ci;
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dlaci=(k5/(1+(ci/km3)^n3))+((k6*(lam/km4)^n4)/(1+(lam/km4)^n4))-k7*laci;
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dgfp=(k8/(1+(laci/km5)^n5))-k9*gfp;
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dX=[dahl dlam dci dlaci dgfp]';

Revision as of 11:44, 24 October 2010


Modelling

Wiring Diagram

This is a outline of the regulatory topology of the concentration band-detect architecture.The different components and the way they interact with each other is represented similar to a electronic circuit.We use this as the starting point for building our model.First each of the components of our system was mathematically formulated. The components were then put together to form the whole system.

Wiring Diagram Concentration Band-Detect

Model

Results

Band detect Model
Band detect Model
Band detect Model

Code

odeIGEM03.m

 %lambda1 function file

function dX =odeIGEM02(t,X,P)

k1=P(1); k2=P(2); k3=P(3); k4=P(4); k5=P(5); k6=P(6); k7=P(7); k8=P(8); k9=P(9); k10=P(10); k11=P(11);

km1=P(12); km2=P(13); km3=P(14); km4=P(15); km5=P(16);

ahl=X(1); lam=X(2); ci=X(3); laci=X(4); gfp=X(5);

n1=1; n2=1; n3=1; n4=1; n5=2;

dlam=((k1*(ahl/km1)^n1)/(1+(ahl/km1)^n1))-k2*lam; dahl=0;%k10*ahl-k11*ahl; dci=((k3*(lam/km3)^n2)/(1+(lam/km3)^n2))-k4*ci; dlaci=(k5/(1+(ci/km3)^n3))+((k6*(lam/km4)^n4)/(1+(lam/km4)^n4))-k7*laci; dgfp=(k8/(1+(laci/km5)^n5))-k9*gfp;

dX=[dahl dlam dci dlaci dgfp]';