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Team:Imperial College London
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{| style="width:900px;background:#f5f5f5;text-align:justify;font-family: helvetica, arial, sans-serif;color:#555555;margin-top:5px;" cellspacing="20" | {| style="width:900px;background:#f5f5f5;text-align:justify;font-family: helvetica, arial, sans-serif;color:#555555;margin-top:5px;" cellspacing="20" | ||
|style="font-family: helvetica, arial, sans-serif;font-size:2em;color:#ea8828;"|About iGEM | |style="font-family: helvetica, arial, sans-serif;font-size:2em;color:#ea8828;"|About iGEM | ||
Revision as of 16:49, 17 October 2010
| Abstract | |
| “More than two billion people around the world live with unrelenting illness due to parasites” - WHO Director General Lee Jong-wook.
Synthetic biology offers great opportunity for biosensors, however current designs require hours before useful output. To tackle this issue in the field, it's crucial that our project can respond in minutes, hence we have engineered a fast, modular sensor framework. This allows detection of a range of different parasites, and may also be used as an environmental tool for mapping their spread.
We have developed two new technologies that enable our modular input/output - a novel cell surface biosensor, customisable for specific parasitic proteases, linked through quorum-sensing to a new 'fast-response' module capable of producing a detectable output in minutes. To demonstrate the concept, we've designed and fabricated B. subtilis to give a striking colour readout upon detecting the waterborne Schistosoma parasite which affects 200 million people worldwide. |
| Pictures | |
| About iGEM | Sponsored By |
| The International Genetically Engineered Machine competition allows teams of undergraduate students from universities all over the world to create projects within the field of Synthetic Biology. Working over the summer, we travel to MIT in November to present our achievements. |
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