Team:Uppsala-SwedenWeek4

From 2010.igem.org

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(Week-4)
(Week-4)
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== Week-4 ==
== Week-4 ==
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We studied the below articles for getting an understanding of how to achieve our goals:
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We studied the below articles for getting an understanding of how to achieve our goals. Having studied each of the articles we had extensive discussions on "Google Wave" and during our off-line group meetings.
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An article about the design of toggle switches and an oscillator, later used for pattern generation
1) Danino etal 2010 (http://www.ncbi.nlm.nih.gov/pubmed/20090747)
1) Danino etal 2010 (http://www.ncbi.nlm.nih.gov/pubmed/20090747)
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A general paper about synthetic biology for better understanding of what we were getting into
2) Mukherji etal 2009 (http://www.ncbi.nlm.nih.gov/pubmed/19898500)
2) Mukherji etal 2009 (http://www.ncbi.nlm.nih.gov/pubmed/19898500)
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The papers about quorum sensing using AHL for pattern generation. These two papers played a major role in driving our project.
3) Basu etal  (http://www.ncbi.nlm.nih.gov/pubmed/15858574 and http://www.ncbi.nlm.nih.gov/sites/pubmed/15096621)
3) Basu etal  (http://www.ncbi.nlm.nih.gov/pubmed/15858574 and http://www.ncbi.nlm.nih.gov/sites/pubmed/15096621)
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4) Original paper about toggle switches (http://www.ncbi.nlm.nih.gov/pubmed/10659857)
4) Original paper about toggle switches (http://www.ncbi.nlm.nih.gov/pubmed/10659857)
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5) For degrdation of color proteins -ex:carotenoids (http://www.jbc.org/content/281/15/9845.full)
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5) For degrdation of color proteins -ex:carotenoids (http://www.jbc.org/content/281/15/9845.full). We planned to degrade the colors generated by the clock display unit after displaying the time for a short duration.
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Having studied the articles we decided to make use of the band detect concept introduced in Basu etal to send and detect the signals between adjacent colonies without being affected by the noise from other colonies.
Having studied the articles we decided to make use of the band detect concept introduced in Basu etal to send and detect the signals between adjacent colonies without being affected by the noise from other colonies.

Revision as of 08:35, 26 September 2010

Week-4

We studied the below articles for getting an understanding of how to achieve our goals. Having studied each of the articles we had extensive discussions on "Google Wave" and during our off-line group meetings.

An article about the design of toggle switches and an oscillator, later used for pattern generation

1) Danino etal 2010 (http://www.ncbi.nlm.nih.gov/pubmed/20090747)

A general paper about synthetic biology for better understanding of what we were getting into

2) Mukherji etal 2009 (http://www.ncbi.nlm.nih.gov/pubmed/19898500)

The papers about quorum sensing using AHL for pattern generation. These two papers played a major role in driving our project.

3) Basu etal (http://www.ncbi.nlm.nih.gov/pubmed/15858574 and http://www.ncbi.nlm.nih.gov/sites/pubmed/15096621)

4) Original paper about toggle switches (http://www.ncbi.nlm.nih.gov/pubmed/10659857)

5) For degrdation of color proteins -ex:carotenoids (http://www.jbc.org/content/281/15/9845.full). We planned to degrade the colors generated by the clock display unit after displaying the time for a short duration.

Having studied the articles we decided to make use of the band detect concept introduced in Basu etal to send and detect the signals between adjacent colonies without being affected by the noise from other colonies.