Team:Mexico-UNAM-CINVESTAV/Modeling/Theory

From 2010.igem.org

We designed a model of the Cold shock reponse system in bacteria by describing each possible interaction between the cold shock proteins (CSP's) and the cold induced proteins (CIP's) and the non-cold induced proteins (non-CIP) in bacteria. (see Figure 1)

After a complete research in the literature we realized that the amount of interaction between genes, mRNAS, proteins, enzymes, etc was very high. Then we tried to describe only the more significant behaivour of cold shock response system (Figure 2) with special attention to the major cold shock protein: Cold shock protein A (CspA).

Figure 2: Schematic view of several genes involved in cold shock protein A regulation system

Simplified cold shock protein A system

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