Team:METU Turkey

From 2010.igem.org

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                 <h3>Abstract..</h3>
                 <h3>Abstract..</h3>
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                     <p><img src="https://static.igem.org/mediawiki/igem.org/4/4d/MTLogoE-co_sensor.jpg" alt="" style="border: 0px solid ; width: 200px; height: 200px;/>As the field of Synthetic Biology is on the rise, iGEM is growing up very  fast and the number of parts in the parts registry is increasing with the  addition of more complex parts each day. After facing some difficulty while  running our algorithms on the parts registry, the need for standardization of   parts entry was apparent. <a href="https://2010.igem.org/Team:METU_Turkey/Project" class="continue">Read More...</a></p>                                         
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                     <p><img src="https://static.igem.org/mediawiki/igem.org/4/4d/MTLogoE-co_sensor.jpg" alt="" style="border: 0px solid ; width: 200px; height: 100px;/>Cells can sense and respond to the presence of various gas molecules such as oxygen, nitrogen and carbon monoxide using gas sensor proteins. CooA is a carbon monoxide (CO) sensing transcription factor. It is a member of the cAMP receptor protein (CRP)/fumavate nitrate reduction (FNR) family of transcriptional regulators. CooA switches on oxidation enzymes in Rhodospirillum rubrum (a purple, nonsulfur, phototrophic bacterium) which enables the bacterium to use CO as a carbon source. CO is an odorless and colorless gas which can be extremely lethal. Our aim is to develop a cell sensor which can detect a wide range of CO concentration in the environment. We are building CooA and CooA-responsive promoter biobricks which will be transformed into E.coli. Fluorescent proteins (GFP and RFP) will be utilized as dose-responsive signals of ambient CO.<a href="https://2010.igem.org/Team:METU_Turkey/Project" class="continue">Read More...</a></p>                                         
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Revision as of 13:21, 23 October 2010

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