"
Team:Imperial College London/Modelling/Signalling
From 2010.igem.org
(Difference between revisions)
(equations) |
m |
||
| Line 31: | Line 31: | ||
|<html><h2>Download Matlab files</h2></html> | |<html><h2>Download Matlab files</h2></html> | ||
|- | |- | ||
| + | |Using the Law of Mass Action, we can rewrite these 4 equations: | ||
| + | |- | ||
| + | | | ||
Revision as of 15:16, 24 October 2010
| Signalling Model |
Objectives |
Detailed description |
| We assuming steady-state for AIP, Phosphate, ComD and ComE in our cell/in the solution. Hence, we can neglect production and degradation rates of ComD and ComE. |
| Equation 1: AIP binds to ComD receptor to form a complex (AIP-ComD) |
| AIP + ComD ↔ AIP-ComD |
| Equation 2: Phosphate binds to the AIP-ComD complex to form another complex (AIP-ComD*) |
| AIP-ComD + Phosphate ↔ AIP-ComD* |
| Equation 3: ComE binds to the AIP-ComD* recepetor to form another complex (AIP-ComD*-ComE) |
| AIP-ComD* + ComE ↔ AIP-ComD*-ComE |
| Equation 4: Phosphate group on ComD binds to ComE and forms two products: phosphorylated ComE (ComE*) and AIP-ComD |
| AIP-ComD*-ComE ↔ AIP-ComD + ComE* |
Parameters & Constants |
Results |
Download Matlab files |
| Using the Law of Mass Action, we can rewrite these 4 equations: |
