Team:Aberdeen Scotland

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Our team aimed to engineer a genetic toggle switch that would allow yeast to express either green or cyan fluourescent protein mutually exclusively.  This is regulated at the translational level which provides a quicker response than previous switches regulated at the transcriptional level.  This is a novel mechanism previously untried.  We successfully developed mathematical models to predict the possibility and requirements for this switch to work whilst biologically we were able to show that that such a swith was possible by building and testing the individual constructs of the switch mechanism.
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Our team aimed to engineer a genetic toggle switch that would allow yeast to express either green or cyan fluorescent protein mutually exclusively.  This is regulated at the translational level which provides a quicker response than previous switches regulated at the transcriptional level.  This is a novel mechanism previously untried.  We successfully developed mathematical models to predict the possibility and requirements for this switch to work whilst biologically we were able to show that that such a switch was possible by building and testing the individual constructs of the switch mechanism.
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Revision as of 08:43, 13 September 2010

University of Aberdeen - ayeSwitch - iGEM 2010

Our team aimed to engineer a genetic toggle switch that would allow yeast to express either green or cyan fluorescent protein mutually exclusively. This is regulated at the translational level which provides a quicker response than previous switches regulated at the transcriptional level. This is a novel mechanism previously untried. We successfully developed mathematical models to predict the possibility and requirements for this switch to work whilst biologically we were able to show that that such a switch was possible by building and testing the individual constructs of the switch mechanism.


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