Team:Northwestern/Project/Apoptosis

From 2010.igem.org

Revision as of 04:06, 23 October 2010 by Cyu286 (Talk | contribs)


Tech Institute
Home Brainstorm Team Acknowledgements Project Human Practices Parts Notebook Calendar Protocol Safety Links References Media Contact

We used the Apoptosis Cassette by Brown '08 iGEM team (K124017).

The bacteriophage cassette includes S105 protein (Holin), R protein (Endolysin), and Rz protein, all of which act in combination to lyse the bacteria.

Holin is a small membrane protein that produces holes in the membrane.

R is an endolysin that digests and cleaves the cell wall.

Rz protein, a periplasmic protein, through reasons that are not yet totally clear, carries out the final step of host lysis.