Team:Northwestern/Brainstorm
From 2010.igem.org
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+ | B-Cell/T-Cell Response Modeling |
Revision as of 19:47, 28 June 2010
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Contents |
Round 1: Group Brainstorming Session
Health/Medicine
32) Release in presence of wound signal (pH) Factor VIII 33) Symbiosis with human body 34) Selective phagocytosis (absorb toxin) 35) Selective phagocytosis (lead) 36) Phagocytosis for drug overdoses 67) Drug sensing bactera 69) Bacterial spermicide 24) Drug delivery method through WBC 25) Apoptosis with drug delivery when disease is recognized 26) Vitamin and mineral delivery 62) Bacteria that takes up excess ions in the body 5) Self Healing material: growth factor 7) Apoptosis in presence of a particular disease 16) Swine Flu testing on site 37) Target bad cells selectively based on offset in circadian rythmn 39) Cure celiac’s with bacteria 40) Ethrypoeitin production in e. coli 41) Thrombolytics in presence in LDL 42) Thrombolytics in precense of clots (macrophages) 43) Bacterial pacemakers
Food/Energy
30) Supplementary vitamin and minerals to be grown on produce 31) Removable pesticide bacterial film 70) Cheese reservatrol 21) Splitting Hydrogen from water 18) Electrogenesis: produce voltage from bacteria
Environment
28) Consume gases in the air (ozone) 29) Consume (CFCs) 23) On site radiation testing (make it click like a Geiger counter) 13) Breaking down plastics (look at past presentation) 44) Photo-driven battery
Manufacturing/Industrial
66) Trace explosive Bacteria 68) EXPLODING BACTERIA 71) Bacterial Superglue 19) Resistors 20) Capacitors (Storing charge) 55) Phagocytosis for water in shoes 56) Bacterial barometer 61) Bacterial paper to print on 2) Active pH buffer for e. coli (target pH) 3) pH meter 48) Cilia creating fluid flow, generating fluid current 50) Create ferrofluuid to create magnetism 51) Bacteria to regulate the temperature of a surface (endothermic and exothermic reaction) 52) Long lasting bacterial sunblock 53) Bacterial Clothing 54) Thermal heating for toes 11) Adjusting Young’s Modulus 12) Contracting group of cells 14) Thermometer 38) Bacterial film that responds to laser so you can sketch on it. (express GFP light induced promotor) 45) Bacterial Gears
Miscellaneous
64) ELISA for DNA 65) ELISA for mRNA 22) Magnetic Bacteria 27) Faster biodegradation (Signal activated ) (isn't this environmental?) 57) Oncoprotein expressed on the outside missing ligand binding portion 58) Cytoskeleton in bacteria 59) Engineering current flow intracellularly 60) Bacterial gyroscope 63) Bacterias that produce primers 1) Proteosome into e. coli design system to keep at steady state to keep e. coli alive 4) Nail polish (grow back or fade away) 6) Tight junctions into bacteria 8) Synthetic Apoptotic signal (and isn't this medical?) 9) Music Playing Bacteria: loudspeaker 46) Clock using bacterial gears 47) Non Newtonian fluid bacteria (using force) 49) Bacteria piston using sinking and floating mechanism 10) Gap junction music playing 15) Rotifers: surviving without water mechanism (protein protection) 17) Engineering signal glycoproteins into bacteria (integration of virus disrupts reporter gene)
Round 2: Official 2010 iGEM Draft
Each member chose 3 favorite topics to research
Sean - Opsin, Electrogenesis, Tight Junction
Avi - Proteosome, Storing Charge, Magnetic Field
Ben - Pacemaker, Factor8, Excess Ion uptake
Matt - Self Healing Material, WBC, Bacterial Thermometer
Timi - Splitting Water, Primer Production, Oncoprotein Express
Jeremy - Circadian Rhythm, pH meter, Cytoskeleton
Ragan - Selective Phagocytosis, Erythropoietin Production, Inducible Apoptosis
Round 3: Presentation and Voting
Voted on the basis of: Sexiness, Available Parts, Feasibility, and Applications
Narrowed Down to: Cytoskeleton, Magnetic Bacteria, and Self Healing Armor
Round 4: Group Discussion
Cytoskeleton Discarded
Self-Healing Armor altered to Bacterial Skin
Magnetic Bacteria relegated to side project
Round 5: Presentation and Voting 2
Bacterial Skin
B-Cell/T-Cell Response Modeling