Team:TU Delft/Team/previous-teams

From 2010.igem.org

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(TU Delft iGEM Team 2009 - BACTERIAL RELAY RACE)
(TU Delft iGEM Team 2008 - ENGINEERING A BIOTHERMOMETER)
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Read more on the [https://2009.igem.org/Team:TUDelft TU Delft iGEM Team 2009 Wiki]
Read more on the [https://2009.igem.org/Team:TUDelft TU Delft iGEM Team 2009 Wiki]
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[[Image:System.png|thumb|300px|right|Black box representation of the biothermometer, with temperature as input and color as output. The system can be split into two subsystems: A temperature sensitive input system and a color producing output system. The temperature sensitive input system works as a switch, switching on the output system at a certain temperature.]]
===TU Delft iGEM Team 2008 - ENGINEERING A BIOTHERMOMETER===
===TU Delft iGEM Team 2008 - ENGINEERING A BIOTHERMOMETER===
The teams goal was to construct a temperature-sensing bacteria Escherichia coli that changes color at different temperatures. Such a thermometer can be applied e.g. as a temperature reporter system in large-scale fermentations, or as a temperature-inducible protein production system.
The teams goal was to construct a temperature-sensing bacteria Escherichia coli that changes color at different temperatures. Such a thermometer can be applied e.g. as a temperature reporter system in large-scale fermentations, or as a temperature-inducible protein production system.

Revision as of 09:46, 13 September 2010

This is the third year the TU Delft is joining the iGEM competition. Considering the success of previous teams, the expectations are high.

TU Delft iGEM Team 2009 - BACTERIAL RELAY RACE

The teams aim was to build an improved cell to cell communication system. They were attempting to construct an E.coli strain which is capable of passing a GFP (Green Fluorescent Protein) signal through conjugation. This mechanism provides the ability of transferring genetic material between bacteria through direct cell to cell contact. A delayed self destructing mechanism caused the destruction of the genetic material of the donor cell after the transfer. The idea is comparable to a relay race, and an illustrative animation discribing this project can be found to the right.

Reward: Gold medal and award for ‘Best Information Processing Project’.

Read more on the TU Delft iGEM Team 2009 Wiki

File:System.png
Black box representation of the biothermometer, with temperature as input and color as output. The system can be split into two subsystems: A temperature sensitive input system and a color producing output system. The temperature sensitive input system works as a switch, switching on the output system at a certain temperature.

TU Delft iGEM Team 2008 - ENGINEERING A BIOTHERMOMETER

The teams goal was to construct a temperature-sensing bacteria Escherichia coli that changes color at different temperatures. Such a thermometer can be applied e.g. as a temperature reporter system in large-scale fermentations, or as a temperature-inducible protein production system.

If the temperature exceeds a certain threshold, a sensitive RNA structure opens up and the ribosome (a molecular protein manufacturing machine) can bind to the RNA. This results in the production of a color compound - Farnesyl PyroPhosphate (FPP).

Reward: Golden medal and the trophy for the ‘Best Wiki’.

Read more on the TU Delft iGEM Team 2008 Wiki