Team:Imperial College London/Achievements

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|style="font-family: helvetica, arial, sans-serif;font-size:2em;color:#ea8828;"|Achievements
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|style="font-family: helvetica, arial, sans-serif;font-size:2em;color:#ea8828;" colspan="2"|Achievements
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|style="width:60px;"|'''We have:'''
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<img style="width:30px;" src="https://static.igem.org/mediawiki/2010/5/56/ICtickicon.png" />
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|Had a fantastic summer, '''learned loads''' and formed '''new friendships'''.
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<img style="width:30px;" src="https://static.igem.org/mediawiki/2010/5/56/ICtickicon.png" />
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|Tackled the problem of '''Neglected Tropical Diseases''' for the '''first time''' in the iGEM competition.
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<img style="width:30px;" src="https://static.igem.org/mediawiki/2010/5/56/ICtickicon.png" />
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|Submitted '''[https://2010.igem.org/Team:Imperial_College_London/Parts 23 documented parts]''' to the registry.
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<img style="width:30px;" src="https://static.igem.org/mediawiki/2010/5/56/ICtickicon.png" />
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|Developed '''integration vectors''' for BioBrick parts and devices which allow integration of cassettes into the ''B. subtilis'' genome, resulting in '''disruption of essential genes'''. Dif excision allows '''removal of antibiotic resistance genes''' from our cassettes.
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<img style="width:30px;" src="https://static.igem.org/mediawiki/2010/5/56/ICtickicon.png" />
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|Extensively '''characterized the existing BioBrick part, 'XylE reporter gene with RBS' ''' (BBa_J33204).
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<img style="width:30px;" src="https://static.igem.org/mediawiki/2010/5/56/ICtickicon.png" />
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|Submitted '''new coding parts''' such as the histidine kinase ComD (K316015).
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<img style="width:30px;" src="https://static.igem.org/mediawiki/2010/5/56/ICtickicon.png" />
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|Shown that the '''novel engineered BioBrick part''', GFP-XylE (BBa_K316007) works as expected.
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<img style="width:30px;" src="https://static.igem.org/mediawiki/2010/5/56/ICtickicon.png" />
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|Submitted a very useful, modular and '''natural BioBrick Part''', the LytC cell wall binding domain (CWBD).
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|-
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<img style="width:30px;" src="https://static.igem.org/mediawiki/2010/5/56/ICtickicon.png" />
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|Designed a '''[https://2010.igem.org/Team:Imperial_College_London/Software_Tool software tool]''' for protease detection and protein presentation on the surface of ''B. subtilis'' using the LytC CWBD.
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<img style="width:30px;" src="https://static.igem.org/mediawiki/2010/5/56/ICtickicon.png" />
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|Explored the [https://2010.igem.org/Team:Imperial_College_London/Human_Practices Human Practices] aspects of our project including the '''ethical, social, environmental, economic and political implications''' of our detection kit including the setting in which it would be implemented.
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<img style="width:30px;" src="https://static.igem.org/mediawiki/2010/5/56/ICtickicon.png" />
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|Based our specifications on '''[https://2010.igem.org/Team:Imperial_College_London/Modelling modelling]''' and '''[https://2010.igem.org/Team:Imperial_College_London/Human_Practices human practices]'''.
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<img style="width:30px;" src="https://static.igem.org/mediawiki/2010/5/56/ICtickicon.png" />
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|Managed to get loads of '''[https://2010.igem.org/Team:Imperial_College_London/Results experimental results]'''!
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<img style="width:30px;" src="https://static.igem.org/mediawiki/2010/5/56/ICtickicon.png" />
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</html>
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|Completed the whole iteration through the '''engineering design cycle for each module''' of our system.
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|-
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<img style="width:30px;" src="https://static.igem.org/mediawiki/2010/5/56/ICtickicon.png" />
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</html>
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|Explored the '''production and implementation considerations''' that we thought might be important in the manufacture of Parasight as a viable product.
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|-
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<img style="width:30px;" src="https://static.igem.org/mediawiki/2010/5/56/ICtickicon.png" />
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</html>
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|Investigated the '''[https://2010.igem.org/Team:Imperial_College_London/Results safety implications]''' of the project as a whole.
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|-
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<img style="width:30px;" src="https://static.igem.org/mediawiki/2010/5/56/ICtickicon.png" />
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</html>
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|Run a series of '''Synthetic Biology School Workshops''', and provided a '''toolkit for others teams''' follow suit.
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<img style="width:30px;" src="https://static.igem.org/mediawiki/2010/5/56/ICtickicon.png" />
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|'''Helped other iGEM teams''' (including Warsaw, UNAM-Mexico and METU-Turkey) by completing their surveys.
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|-
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|We have:
 
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* Had a fantastic summer, learnt loads and formed new friendships.
 
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* Run a series of Synthetic Biology School Workshops, and have provided tools for others to follow suit.
 
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* Outline and detail a new approach to an issue of Human Practice in synthetic biology as it relates to your project, such as safety, security, ethics, or ownership, sharing, and innovation (PyrD and AmyE vectors and Dif excision of antibiotic resistance genes).
 
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* Tackled the problem of Neglected Tropical Diseases for the first time in the iGEM competition.
 
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* Characterized/improved the following existing BioBrick Parts/Devices and enter this information back on the Registry:
 
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* Designed a software tool for protease detection and protein presentation on the surface of ''B. subtilis''.
 
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* New Natural BioBrick Part, LytC CWBD
 
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* New Engineered BioBrick Device, GFP-XylE
 
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* Characterized the operation of at least one new BioBrick Part or Device and entered this information on the Parts or Device page via the Registry of Parts
 
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* Based our specifications on modelling.
 
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* Characterised modules in both ''B. subtilis'' and ''E. Coli''.
 
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* Managed to get loads of experimental measurements.
 
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Latest revision as of 03:17, 28 October 2010

Achievements
We have:
Had a fantastic summer, learned loads and formed new friendships.
Tackled the problem of Neglected Tropical Diseases for the first time in the iGEM competition.
Submitted 23 documented parts to the registry.
Developed integration vectors for BioBrick parts and devices which allow integration of cassettes into the B. subtilis genome, resulting in disruption of essential genes. Dif excision allows removal of antibiotic resistance genes from our cassettes.
Extensively characterized the existing BioBrick part, 'XylE reporter gene with RBS' (BBa_J33204).
Submitted new coding parts such as the histidine kinase ComD (K316015).
Shown that the novel engineered BioBrick part, GFP-XylE (BBa_K316007) works as expected.
Submitted a very useful, modular and natural BioBrick Part, the LytC cell wall binding domain (CWBD).
Designed a software tool for protease detection and protein presentation on the surface of B. subtilis using the LytC CWBD.
Explored the Human Practices aspects of our project including the ethical, social, environmental, economic and political implications of our detection kit including the setting in which it would be implemented.
Based our specifications on modelling and human practices.
Managed to get loads of experimental results!
Completed the whole iteration through the engineering design cycle for each module of our system.
Explored the production and implementation considerations that we thought might be important in the manufacture of Parasight as a viable product.
Investigated the safety implications of the project as a whole.
Run a series of Synthetic Biology School Workshops, and provided a toolkit for others teams follow suit.
Helped other iGEM teams (including Warsaw, UNAM-Mexico and METU-Turkey) by completing their surveys.
Retrieved from "http://2010.igem.org/Team:Imperial_College_London/Achievements"