Team:Imperial College London/Achievements

From 2010.igem.org

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Revision as of 23:02, 27 October 2010

Department of Bioengineering

Division of Molecular Biosciences

Achievements
We have:
	Had a fantastic summer, learnt loads and formed new friendships.
	Run a series of Synthetic Biology School Workshops, and provided tools for others to follow suit.
	Submitted 23 documented parts to the registry.
	Developed integration vectors for BioBrick parts and devices which allow integration of cassettes into the B. subtilis genome, resulting in disription of essential genes. Dif excision allows removal of antibiotic resistance genes from our cassettes.
	Tackled the problem of Neglected Tropical Diseases for the first time in the iGEM competition.
	Extensively characterized the existing BioBrick part, 'XylE reporter gene with RBS' (BBa_J33204).
	Submitted new coding regions for the histidine kinase ComD (K316015) and its response regulator ComE (K316016).
	Designed a software tool for protease detection and protein presentation on the surface of B. subtilis.
	Submitted a very useful, modular and natural BioBrick Part, the LytC CWBD.
	Shown that the novel engineered BioBrick part, GFP-XylE (BBa_K316007) works as expected.
	Based our specifications on modelling and human practices.
	Explored the https://2010.igem.org/Team:Imperial_College_London/Human_Practices Human Practices] aspects of our project including the ethical, social, environmental, economic and political implications of our detection kit including the setting in which it would be
	Managed to get loads of experimental results!
	Helped other iGEM teams (including Warsaw, UNAM-Mexico and METU-Turkey) by completing their surveys.
	Completed the whole iteration through the engineering cycle for each module of our system.
	Explored the Manufacturing Considerations that we thought important to manufacture Parasight as a viable product.
	Investigated the safety implications of the project as a whole.

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-|Contributed the PyrD and AmyE vectors to the registry and have used Dif excision to remove antibiotic resistance genes from our cassettes.
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-|Extensively characterized the existing BioBrick part, 'XylE reporter gene with RBS (BBa_J33204).
+|Extensively characterized the existing BioBrick part, 'XylE reporter gene with RBS' (BBa_J33204).
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-|Developed integration vectors for BioBrick parts and devices which can allow integration of various cassettes into the ''B. subtilis'' genome, allowing disription of essential genes.
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-|Based our design specifications on computer modelling, which enabled us to decide which ideas should be implemented in our design.
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