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Photinus Pyralis (Firefly Luciferase)

EPIC luciferase

luxCDABE (Vibrio Fischeri/Harvyi)


  • Gram-negative,bioluminescent, marine bacteria in the genus vibrio
  • rod-shaped, motile (via polar flagella),
  • facultatively anaerobic
  • halophilic (extremophile for high salt)
  • competent for both fermentative and respiratory metabolism.
  • grow between 4°C and 35°C.
  • lacks a LuxI/R quorum sensing system(which fischeri uses), instead employs a hybrid quorum-sensing circuit, detecting its autoinducer via a membrane-bound histidine kinase and using a phosphorelay.