Team:Aberdeen Scotland

Our team aimed to engineer a genetic toggle switch that would allow yeast to express either green or cyan fluourescent protein mutually exclusively. This is regulated at the translational level which provides a quicker response than previous switches regulated at the transcriptional level. This is a novel mechanism previously untried. We successfully developed mathematical models to predict the possibility and requirements for this switch to work whilst biologically we were able to show that that such a swith was possible by building and testing the individual constructs.

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