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Team:IIT Madras
From 2010.igem.org
This is a template page. READ THESE INSTRUCTIONS.
You are provided with this team page template with which to start the iGEM season. You may choose to personalize it to fit your team but keep the same "look." Or you may choose to take your team wiki to a different level and design your own wiki. You can find some examples HERE.
You MUST have a team description page, a project abstract, a complete project description, a lab notebook, and a safety page. PLEASE keep all of your pages within your teams namespace.
File:IIT Madras logo.png 200px | ||||||
| 6th most common cause of death worldwide.India contributes 1 in 25 of diabetes cases every year. The World Health Organisation |recently reported that up to 245 million people suffer from diabetes worldwide. It is estimated that diabetes consumes between 5 to |10% of the world's health care expenditure, and this is expected to go up to 12% in the next 20 years. There is, however, no known |cure to this epidemic, and our only hope is to fall back to the old adage, 'Prevention is better than cure'. It has been known for a |while that reducing the calories consumed in the form of sugar will help in the prevention of this disease. To date, seven different |sweetening proteins have been identified and approved for consumption by the FDA. However, these proteins face several issues in |production, separation and purification, making them an ideal candidate for further work, particularly focusing on expression and |regulation. | buttermilk and curds, to produce Monellin, a heat and pH stable sweetening protein. If we are successful in engineering |Lactobacillus lactis, a Gram positive bacteria to express and secrete Monellin, we will be able to produce dairy products low in |poly-saccharide-based sweeteners, radically reducing the calorific content of these products. In order to be able to control the |level of expression in this system, we plan to develop a regulatory system(s) that can be tweaked to suit varied purposes. | on their sweet-tooth. |  Your team picture | |||
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