Team:ETHZ Basel/Modeling/Stochastic Simulations

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Open Issues

Debating Questions

Why would stochastic simulation (on the molecular level) be good:
• It sounds more cool than ODE – based models;
• It generally gives (or at least it should give) a more realistic view of the biological process studied;
• Individual complexes could be traced all through the simulation (not sure if we’d ever need that; probably not).

Why would stochastic simulation (on the molecular level) not be of interest:
• In terms of the results, the predicted values of the CheY concentration levels fluctuate around the deterministically obtained ones, with amplitude of fluctuations indirectly proportional to population size (number of molecules).

Existing Stochastic Models

Introduction

StochSim