Malaria

Malaria is a parasitic disease killing more than 1 million people every year, in tropical and subtropical countries. This disease is transmitted when a mosquito takes its bloodmeal from a human infected with malaria. The parasite infects the mosquito, develops inside of it and finally is transmitted to the next person the mosquito bites.

EPFL iGEM team decided to try to act on the mosquito stage, by preventing the ookinete to cross the midgut epithelium and transform into an oocyst.