Overview

The aim of our project is to help stopping the propagation of Malaria. To do so, we chose to act on the mosquito. Indeed, if we prevent the mosquito from being infected by malaria, it won't be able to transmit the parasite to healthy humans.

Our idea is to engineer Asaia, a bacterium that is naturally present in the mosquito's intestinal tract.

This bacteria would express an immunotoxin and specific proteins to kill the plasmodium or prevent its entry into the epithelium.

The immunotoxin and the proteins then fight the plasmodium and thus prevent the mosquito infection.

So... ASAIA is the pink power against malaria.....

For a playful overview of our project, you can watch our great movie iGEM EPFL movie