Team:Stockholm/Modelling/Final eq

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Yildirim N et al model

In a series of 5 equations, They proposed dynamics for mRNA production, β-galactosidase production, Allolactose, Lactose for Lac operon. In their model they also considered transcriptional and translational delays (ie. β-galactosidase and β-galactoside permease production from mRNA is not instant and takes time). [Here model for yildirim et al will come]

Simplified model

This model can be simplified. Ahmadzadeh et al. 2005 proposed a simplified model of [http://www.ncbi.nlm.nih.gov/pubmed/12719218 Yildirim N et al 2002], where they ignored time delays for transcription and translation. For more simplification they also assumed that β-galactosidase and β-galactoside permease reach their steady state values instantly, ending up with 3 equations just for mRNA, Lactose and Allolactose dynamics.

eq. 3.1: mRNA dynamics eq.