Team:Cambridge/HIV Diagnosis
From 2010.igem.org
- Yeast pheromones?
- "Co-localization of receptors does not affect the local concentration of unbound ligand, nor the total number of binding events." [http://yeastpheromonemodel.org/wiki/Localization_effects]
- This potentially addresses Anja's concerns
- Process of glycosylation, proteolysis = quite complex, potential problem?
- agr biobricks were not made to work in Bacillus, they would have been the best option
- "Co-localization of receptors does not affect the local concentration of unbound ligand, nor the total number of binding events." [http://yeastpheromonemodel.org/wiki/Localization_effects]
- Theo's conclusion: everything would work except the peptide signal/receptor binding
- Project unfeasible
[http://openwetware.org/wiki/User:Ilya/Yeast/Mating_pheromone_response_pathway/Pheromone]