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Introduction System Modeling Lab note Result Reference

4C3leak switch

We modeled our 4C3 leak switch as ODE system.

Variable

Basically, "pn" denotes for protein concentration and "rn" denotes for mRNA concentration

p1,p2,p3,p4 : concentration of 4 recombinase protein

r1,r2,r3,r4 : concentration of 4 recombinass mRNA

pc,rc : concentration of cre recombinase protein and mRNA

ps,rs : concentration of SP6 polymerase protein and mRNA

Besides, we treated DNA as continuous variabl, since there could be hundreds of plasmid in one E.coli (multicopy plasmid).

equation

parameters

MS2 phage infection

Whole system

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