Team:UC Davis/notebook/overallworkplan.html

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Overall Workplan: The Approach in Designing the Circuit

  • Non-abstracted version of our entire circuit:



  • In building a spatial oscillator, the genetic circuit must fulfill at least 3 main properties.


1. Cells must be able to react to stimuli to start the oscillation.

  • Our circuit is induced with the absence of light (as indicated by the moon symbol) and arabinose (as indicated by the red molecules.)


2. Cells must be able to transform into one of two states.

  • In our circuit, all promoter have dual functions. They are activated or inhibited by specific molecules.


3. Cellular expression must be robust to external environmental perturbations.

  • In our circuit, cell expression is reinforced by positive feedback.


We would like to take a moment to thank all of our sponsors for their very generous donations, as we could not have done this without your help!

We would also like to thank and acknowledge:
Our Advisors
Marc Facciotti
Ilias Tagkopoulos
Technical Guidance
David Larsen
Andrew Yao
Visiting iGEMer
Jia Li of Zhejiang University (TEAM ZJU-China)
cI Promoter Screen
Drew Endy - Stanford
Thomas Schneider - NIH
Want to sponsor us? Send an email to mtfacciotti@ucdavis.edu to discuss various ways you can help! :)

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