Team:Aberdeen Scotland
From 2010.igem.org
University of Aberdeen - ayeSwitch
iGEM 2010
Our team aimed to engineer a genetic toggle switch that would allow yeast to express either green or cyan fluorescent protein mutually exclusively. This is regulated at the translational level which provides a quicker response than previous switches regulated at the transcriptional level. This is a novel mechanism previously untried. We successfully developed mathematical models to predict the possibility and requirements for this switch to work whilst biologically we were able to show that that such a switch was possible by building and testing the individual constructs of the switch mechanism.