Team:Stanford/Research/Modeling

Goals

Our intuition for what makes a good ratio sensor could only take us so far. From the very first stages of design, we wanted to back up and test our ideas with mathematical tools. Luckily, we found that solving the equations of mass action kinetics at steady-state was enough gave us clear design criteria. We present the mathematical basis for sensors that are capable of sensing a single ratio digitally, or many ratios in an analog fashion.

The System

Analog

Digital

Boolean model for the sRNA system. This is mean to provide a significantly simplified mathematical understanding of the dynamics involved.