Team:ETHZ Basel/Internal
From 2010.igem.org
Internal
This section will be removed before wiki-freeze!
DO NOT EDIT NOW!!!
General remarks
- Protein names: normally written
- gene names: italic
- Directed movement NOT running, please correct!
- chemotaxis pathway NOT Chemotaxis nor chemotactic
- E. lemming with space
- E. lemming vs THE E. lemming: E. lemming: Project name (whole assay), The E. lemming: One single genetically modified E. coli
- far-red light, not far red light, please correct!
- internal links - we should refer to other internal pages (hyperlinks) where appropriate, inside the paragraphs.
- in silico & in vivo, not in-silico & in-vivo
Responsibilities
- https://2010.igem.org/Team:ETHZ_Basel
- https://2010.igem.org/Team:ETHZ_Basel/Introduction/Motivation
- https://2010.igem.org/Team:ETHZ_Basel/Introduction/Movie
- https://2010.igem.org/Team:ETHZ_Basel/Introduction/Media
- https://2010.igem.org/Team:ETHZ_Basel/Biology
- https://2010.igem.org/Team:ETHZ_Basel/Biology/Molecular_Mechanism
- https://2010.igem.org/Team:ETHZ_Basel/Biology/Cloning
- https://2010.igem.org/Team:ETHZ_Basel/Biology/Implementation
- https://2010.igem.org/Team:ETHZ_Basel/Biology/Archeal_Light_Receptor
- https://2010.igem.org/Team:ETHZ_Basel/Biology/Safety
- https://2010.igem.org/Team:ETHZ_Basel/Modeling
- https://2010.igem.org/Team:ETHZ_Basel/Modeling/Light_Switch
- https://2010.igem.org/Team:ETHZ_Basel/Modeling/Chemotaxis
- https://2010.igem.org/Team:ETHZ_Basel/Modeling/Movement
- https://2010.igem.org/Team:ETHZ_Basel/Modeling/Combined
- https://2010.igem.org/Team:ETHZ_Basel/Modeling/Experimental_Design
- https://2010.igem.org/Team:ETHZ_Basel/InformationProcessing
- https://2010.igem.org/Team:ETHZ_Basel/InformationProcessing/Microscope
- https://2010.igem.org/Team:ETHZ_Basel/InformationProcessing/InformationFlow
- https://2010.igem.org/Team:ETHZ_Basel/InformationProcessing/CellDetection
- https://2010.igem.org/Team:ETHZ_Basel/InformationProcessing/Visualization
- https://2010.igem.org/Team:ETHZ_Basel/InformationProcessing/Controller
- https://2010.igem.org/Team:ETHZ_Basel/InformationProcessing/Game
- https://2010.igem.org/Team:ETHZ_Basel/Achievements
- https://2010.igem.org/Team:ETHZ_Basel/Achievements/BioBrick_Toolbox
- https://2010.igem.org/Team:ETHZ_Basel/Achievements/Matlab_Toolbox
- https://2010.igem.org/Team:ETHZ_Basel/Achievements/Systems_Design
- https://2010.igem.org/Team:ETHZ_Basel/Achievements/Systems_Implementation
- https://2010.igem.org/Team:ETHZ_Basel/Achievements/Technical_Standard
- https://2010.igem.org/Team:ETHZ_Basel/Team
- https://2010.igem.org/Team:ETHZ_Basel/Team/Photos
- https://2010.igem.org/Team:ETHZ_Basel/Team/Acknowledgements
Suggestions
first paragraph, define 'anchor' and 'tumbling' and 'directed movement' before using the terms
second paragraph: quite unclear, if possible, add more details & explain more
add a few sentences (and link them) regarding ARL & Safety
50 μm (?) high flow channel; remove question mark
in second part of the page, 'cells with highest score'; define the score
clearly define the reference used: [1] Stuurman et al. 2007; could not uniquely identify it
Original sentence 'It should be noticed that this signal changes with time constant in the range of hours' rephrased to:'It should be noticed that this signal constantly changes with time in the range of hours.' Revert if meaning changed.
added reference [2]. would be good if a biologist can check if it's the right one. Looks like the page ends abruptly. something like a conclusion perhaps?
spacing, subheadings & some bullet points); suggesting more images for the user experience part
Corrected minor spelling mistakes. Gave names to the 2 steps of the cell detection algorithm. Added subheadings to make it more readable & structured. Revert if necessary.
check with biology to keep it updated (check list)
Add link to Biozentrum Unibas.
Christoph will do this by Sunday
- https://2010.igem.org/Team:ETHZ_Basel/Modeling : first proofreading Simona DONE
Christoph:
- first box: E. lemming, these aren't the devices we used for modeling, that is what we model, anchor not necessarily the plasmid
- too many "in order to"
- mathematical modeling overview: please rearrange: 1. WHAT complex model set up, consisting of chemotaxis, light, move, implemented and coupled 2. WHY explain support a little bit more
- Model implementation: tab and text order should be equal; implementation and adaption of literature described ones, movement by our own!
- Combined mathematical models: shouldn't light-switch-chemo-movement be the complete?
- https://2010.igem.org/Team:ETHZ_Basel/Modeling/Combined#Light_switch_-_Chemotaxis : interfaces had to be defined, show that the individual models are without restrictons combinable by user wish, number of combinations
- https://2010.igem.org/Team:ETHZ_Basel/Modeling/Light_Switch
- "To model the relocation, we decided to adapt a model recently published by Sorokina et al [1]. As a first step we reimplemented the model as published in the paper." make one good sentence
- https://2010.igem.org/Team:ETHZ_Basel/Modeling/Chemotaxis: first proofreading Simona DONE
C: give an idea about the complexity, e.g. high number of proteins and interactions; why did we use only Spiro and Mello?; models: text first as it explains the plots; please gibe a clearer description of the plots, for an external person it's almost not understandable
- https://2010.igem.org/Team:ETHZ_Basel/Modeling/Movement
- make clear we did this completely on our own, not implemented but created!; Great section!!! 'THANKS!!!
- https://2010.igem.org/Team:ETHZ_Basel/Modeling/Combined C: see above
- https://2010.igem.org/Team:ETHZ_Basel/Modeling/Experimental_Design C: OK