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Team:UCL London
From 2010.igem.org
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PROJECT
UCL’s Biochemical engineering department has been at the forefront of biopharmaceutical manufacture for years. Extraordinary advances in the life sciences have great potential to improve our quality of life through better medicines and a cleaner environment. Our project aims to create somewhat “independent” cells that are capable of self-inducing into the production phase, without the introduction of any chemical into the closed system. By exploiting the genetically modified E.coli to respond to hypoxia, we eliminate the need of IPTG-induction. The functioning genetic circuit would be signalled by the production of a Green Fluorescent Protein.
Approach
Project Hypoxon aims to create cells capable of self-induction into the production phase, without the introduction of any chemical into the closed system. By exploiting genetically modified E.coli to respond to hypoxia, we eliminate the need of IPTG induction. A Green Fluorescent Protein would indicate that the product has theoretically been produced!
ApproachBiobricks
Check out all the biobricks we used
Team
We are an interdisciplinary group of students and advisers. Click on the The Team to find out more. Also watch our video to find out what an exciting and fulfilling summer we've had!
Updates
Keep up to date with what's happening by following us on Twitter, whether it be the creation of new life in the labs, new designs, new sponsors, you know where to be!
Notebook
Want to know exactly what we've been doing on a daily basis and to find out how Project Hypoxon has progressed, visit our Notebook
Public Engagement
Want to read the detailed reports of all the amazing events that we've participated in and organized, then click on the link below.
Sponsors
We would like to thank all our sponsors for their contribution and support throughout this summer project. To find out more about who did what, follow this link.
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