Team:Panama

From 2010.igem.org

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Team Profile</span></a></li>
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Submitted to the Registry</span></a></li>
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Practice</span></a></li>
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<div class="componentheading">Welcome to the Panama Team Wiki for iGEM 2010</div>
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<h3>Republic of Panama</h3>
 +
<p>Situated on the isthmus connecting North and South America, it
 +
is bordered by Costa Rica to the northwest, Colombia to the southeast,
 +
the Caribbean Sea to the north and the Pacific Ocean to the south.</p>
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</div>
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</h3>
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<h3>iGEM PANAMA</h3>
 +
<p>In this picture: Carolina, Yisett, Claudio, Nicole, Lorena,
 +
Grimaldo, Natasha, Laura, Ernesto, Dra. Carmenza, Dr. Rao, Ezequiel</p>
 +
</div>
 +
</div>
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</h3>
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<h3>iGEM PANAMA</h3>
 +
<p>In this picture: Yisett, Silke, Yaraví, Carlos, Dr. Patrick
 +
Nee.</p>
 +
</div>
 +
</div>
 +
</h3>
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<img
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<h3>iGEM PANAMA</h3>
 +
<p>In this picture: Leyda, Zeuz, Laura</p>
 +
</div>
 +
</div>
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</h3>
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<h3>iGEM PANAMA</h3>
 +
<p>Labs.</p>
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</div>
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</h3>
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             <td class="contentheading" width="100%">
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Assembling the enzyme gene Rhamnosiltransferase 1 (rhlAB) into a Biobrick-friendly for rhamnolipid production in E. coli</td>
+
Assembling the enzyme gene Rhamnosiltransferase 1 (rhlAB) into a
-
              
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Biobrick-friendly for rhamnolipid production in E.coli </td>
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            <span class="small"></span>abstract</td>
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             <p style="text-align: left;">PROJECT DESCRIPTION</p>
+
             <p>Rhamnolipids are naturally occurring glycolipids
-
            <p
+
produced by the <span style="font-style: italic;">Pseudomonas
-
style="margin-bottom: 0cm; font-style: normal; line-height: 0.5cm; widows: 2; orphans: 2;"
+
aeruginosa</span>. Rhamnolipids have many applications, because
-
align="justify"><span style="color: rgb(0, 0, 0);"><span
+
of their natural biosurfactant, emulsifying, fungicidal, antibiotic,
-
style="font-family: sans-serif;"><span
+
and pharmaceutical properties. Also rhamnolipids can operate in extreme
-
style="font-size: 0.4cm;">Rhamnolipids are naturally occurring glycolipids produced by the <span style="font-style: italic;"> Pseudomonas aeruginosa</span>. Rhamnolipids have many applications, because of their natural biosurfactant, emulsifying, fungicidal, antibiotic, and pharmaceutical properties. Also rhamnolipids can operate in extreme conditions such as high temperature, pH, and salinity. They have a low toxicity, and they are biodegradable compared to their synthetic chemical counterparts. Rhamnolipid is composed of rhamnose sugar molecule and b-hydroxyalkanoic acid. The rhamnosyltransferase 1 complex (RhlAB) is the key enzyme responsible for transferring the rhamnose moiety to the b-hydroxyalkanoic acid moiety to biosynthesize rhamnolipid.  Since the organisms known to produce rhamnolipids are almost exclusively pathogens. For this reason, we propose the non-pathogenic nature of <span style="font-style: italic;">E. coli</span> as an attractive candidate for commercial rhamnolipid production by assembling our rhlAB gene into a BioBrick using synthetic biology to engineer these new rhlAB producing bacteria for human benefit.</span></span></span></span></p>
+
conditions such as high temperature, pH, and salinity. They have a low
-
 
+
toxicity, and they are biodegradable compared to their synthetic
-
 
+
chemical counterparts. Rhamnolipid is composed of rhamnose sugar
-
<p><span
+
molecule and b-hydroxyalkanoic acid. The rhamnolipids are almost
-
style="font-size: 0.4cm;">Our aim is to construct a BioBrick that leads to the production of rhlAB enzyme complex in <span style="font-style: italic;">E.coli</span>. To accomplish this we must modify the natural gene sequence of rhlAB complex because it includes illegal restriction sites and requires modifications to be fit into a BioBrick. We will perform silent mutations in the gene sequence with a form of mutagenesis. To measure our success we will do bio-assays with our new <span style="font-style: italic;">E. coli rhlAB</span> strain to degrade rhamnose sugars and fatty-acids substrates and turn it in rhamnolipids. We hope that our BioBricks will become a useful tool for the bioengineered industry and widely used as a simple and effective means of rhamnolipid production.</span></p>
+
exclusively pathogens. For this reason, we propose the non-pathogenic
-
<p></p>
+
nature of <span style="font-style: italic;">E.coli</span>
-
<p></p>
+
as an attractive candidate for commercial rhamnolipid production by
-
<p
+
assembling our rhlAB gene into a BioBrick using synthetic biology to
-
  style="text-align: center;margin-bottom: 0cm; font-style: normal; line-height: 0.5cm; widows: 2; orphans: 2;"
+
engineer these new rhlAB producing bacteria for human benefit.
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 +
more...</a> </td>
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in Panamanian NewsPapers </td>
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                  <td colspan="2" class="createdate"
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valign="top"> Saturday, 02 october 2010 </td>
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                  <td colspan="2" valign="top">
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                  <p>A article about our team and synthetic
 +
biology was published in today's of the newspaper <span
 +
style="font-style: italic;">La Prensa</span>.<img
 +
style="width: 160px; height: 107px;" alt="articule"
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src="http://congresosectorinformal.com/igem/temp/New_Project/images/LaPrensa-2-10-2010-mini.jpg"></p>
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class="readon">Read more...</a> </td>
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 +
Interview with our team on Panamanian Public TV </td>
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width="70%"> <span class="small"><br>
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                  </span>&nbsp;
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                  <td colspan="2" class="createdate"
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valign="top"> Saturday, 14 September 2010 </td>
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                  <p>This is a short interview with our team in
 +
SERTV.</p>
 +
                  <p><img style="width: 160px; height: 107px;"
 +
alt="SERTV"
 +
src="http://congresosectorinformal.com/igem/temp/New_Project/images/SERTV-14-09-2010-mini.jpg"></p>
 +
                  </td>
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Last Updated on Thursday, 11 February 2010 21:41 </td>
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 +
class="readon">Read more...</a> </td>
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              <td class="sectiontableentry2" valign="top">
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  <dt class="toggler item1 first"> <span
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 +
-&nbsp;9
 +
Octuber 2010 </span> </span></dt>
 +
  <dd class="content item1 first"> <span
 +
class="article" style="display: block;">
 +
    <p><img
 +
src="http://congresosectorinformal.com/igem/temp/New_Project/images/apanac.png"
 +
alt="dropdown" title="dropdown" align="left"
 +
border="0">Panama's iGEM team presented at the <span
 +
style="font-style: italic;">Thirteenth
 +
National Congress on Science and Technology</span> organized by
 +
APANAC.</p>
 +
    </span> </dd>
 +
  <dt class="toggler item2"> <span class="header-l"><span
 +
class="header-r">17 - 19 october 2010 </span> </span></dt>
 +
  <dd class="content item2"> <span class="article"
 +
style="display: block;">
 +
    <p><img
 +
src="http://congresosectorinformal.com/igem/temp/New_Project/images/ingenio.png"
 +
alt="dropdown" title="dropdown" align="left"
 +
border="0">Panamanian students across the country presented
 +
from Sunday through Tuesday, scientific, technological and innovation
 +
in the <span style="font-style: italic;">XIII National
 +
Science Fair Youth Ingenio</span>.
 +
    </p>
 +
    </span> </dd>
 +
  <dt class="toggler item3"> <span class="header-l"><span
 +
class="header-r">6 - 8 november </span> </span></dt>
 +
  <dd class="content item3"> <span class="article"
 +
style="display: block;">
 +
    <p><img
 +
src="http://congresosectorinformal.com/igem/temp/New_Project/images/jamboree.png"
 +
alt="dropdown" title="dropdown" align="left"
 +
border="0">The iGEM 2010 Jamboree will take place on
 +
November 6th to November 8th, 2010 at MIT in Cambridge, MA.</p>
 +
    </span> </dd>
 +
</dl>
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 +
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 +
      <td>
 +
      <div class="moduletable">
 +
      <h3>Team</h3>
 +
      <p><img
 +
src="http://congresosectorinformal.com/igem/temp/New_Project/images/team-panama.png"
 +
alt="pickjoomla" title="pickjoomla" align="left"
 +
border="0">Our team is composed of 6 students of University
 +
of Panama, 2 students of Technological University of Panama, 5
 +
graduates and 4 phD advisors.</p>
 +
      </div>
 +
      </td>
 +
      <td>
 +
      <div class="moduletable">
 +
      <h3>Human Practices</h3>
 +
      <p><img src="" alt="pickjoomla"
 +
title="pickjoomla" align="left" border="0">We
 +
understand the responssibilities and
 +
challenges issues in new scientific advantage, specially when this are
 +
related with the life conception and manage as Synthetic Biology field.</p>
 +
      </div>
 +
      </td>
 +
      <td>
 +
      <div class="moduletable">
 +
      <h3>Donors</h3>
 +
      <p><img src="" alt="pickjoomla"
 +
title="pickjoomla" align="left" border="0">The
 +
first ever Panamanian team to participate in
 +
the International Genetically Engineered Machine (iGEM) competition
 +
organized by the Massachussetts Institute of Technology (MIT) needs
 +
your support.</p>
 +
      </div>
 +
      </td>
 +
    </tr>
 +
  </tbody>
 +
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</div>
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 +
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<div>Copyright iGEM PANAMA 2010. All Rights
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Revision as of 18:54, 7 October 2010

iGEM Panama

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Republic of Panama

Situated on the isthmus connecting North and South America, it is bordered by Costa Rica to the northwest, Colombia to the southeast, the Caribbean Sea to the north and the Pacific Ocean to the south.

iGEM PANAMA

In this picture: Carolina, Yisett, Claudio, Nicole, Lorena, Grimaldo, Natasha, Laura, Ernesto, Dra. Carmenza, Dr. Rao, Ezequiel

iGEM PANAMA

In this picture: Yisett, Silke, Yaraví, Carlos, Dr. Patrick Nee.

iGEM PANAMA

In this picture: Leyda, Zeuz, Laura

iGEM PANAMA

Labs.

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Assembling the enzyme gene Rhamnosiltransferase 1 (rhlAB) into a Biobrick-friendly for rhamnolipid production in E.coli PDF Print E-mail
abstract

Rhamnolipids are naturally occurring glycolipids produced by the Pseudomonas aeruginosa. Rhamnolipids have many applications, because of their natural biosurfactant, emulsifying, fungicidal, antibiotic, and pharmaceutical properties. Also rhamnolipids can operate in extreme conditions such as high temperature, pH, and salinity. They have a low toxicity, and they are biodegradable compared to their synthetic chemical counterparts. Rhamnolipid is composed of rhamnose sugar molecule and b-hydroxyalkanoic acid. The rhamnolipids are almost exclusively pathogens. For this reason, we propose the non-pathogenic nature of E.coli as an attractive candidate for commercial rhamnolipid production by assembling our rhlAB gene into a BioBrick using synthetic biology to engineer these new rhlAB producing bacteria for human benefit.

READ more...
 
Article in Panamanian NewsPapers PDF Print E-mail
Saturday, 02 october 2010

A article about our team and synthetic biology was published in today's of the newspaper La Prensa.articule

Read more...
 
Interview with our team on Panamanian Public TV PDF Print E-mail

 
Saturday, 14 September 2010

This is a short interview with our team in SERTV.

SERTV

Last Updated on Thursday, 11 February 2010 21:41
Read more...
 

Current Donors


goldsenacytespindicasatesppatrickneeesp

silversosafundacion

esp

brozenpedropletter
 

Academic Sponsors


UTP

UP

smithsonian

 

6 - 9 Octuber 2010

dropdownPanama's iGEM team presented at the Thirteenth National Congress on Science and Technology organized by APANAC.

17 - 19 october 2010

dropdownPanamanian students across the country presented from Sunday through Tuesday, scientific, technological and innovation in the XIII National Science Fair Youth Ingenio.

6 - 8 november

dropdownThe iGEM 2010 Jamboree will take place on November 6th to November 8th, 2010 at MIT in Cambridge, MA.

Follow us on Twiter



Facebook

Team

pickjoomlaOur team is composed of 6 students of University of Panama, 2 students of Technological University of Panama, 5 graduates and 4 phD advisors.

Human Practices

pickjoomlaWe understand the responssibilities and challenges issues in new scientific advantage, specially when this are related with the life conception and manage as Synthetic Biology field.

Donors

pickjoomlaThe first ever Panamanian team to participate in the International Genetically Engineered Machine (iGEM) competition organized by the Massachussetts Institute of Technology (MIT) needs your support.